| 1309299 | Mmel1 | membrane metallo-endopeptidase-like 1 | ENCODES a protein that exhibits metalloendopeptidase activity; zinc ion binding; endopeptidase activity (ortholog); INVOLVED IN proteolysis (ortholog); ASSOCIATED WITH primary biliary cholangitis (ortholog); rheumatoid arthritis (ortholog); FOUND IN extracellular space; endoplasmic reticulum (orthol og); Golgi apparatus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; allethrin; bisphenol A | 5 | 170713602 | 170744058 | Rat | 67 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1319572 | Mmel1 | membrane metalloendopeptidase like 1 | Predicted to enable metalloendopeptidase activity and zinc ion binding activity. Predicted to be involved in protein processing. Located in Golgi apparatus and endoplasmic reticulum. Orthologous to human MMEL1 (membrane metalloendopeptidase like 1). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 154954042 | 154979987 | Mouse | 70 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1603610 | MMEL1 | membrane metalloendopeptidase like 1 | The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008] | 1 | 2590639 | 2633016 | Human | 103 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8947370 | Mmel1 | membrane metalloendopeptidase like 1 | ENCODES a protein that exhibits endopeptidase activity (ortholog); metalloendopeptidase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN proteolysis (ortholog); ASSOCIATED WITH primary biliary cholangitis (ortholog); rheumatoid arthritis (ortholog); FOUND IN endoplasmic reticulum (ortho log); extracellular space (ortholog); Golgi apparatus (ortholog) | NW_004955486 | 8635727 | 8662793 | Chinchilla | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11997945 | MMEL1 | membrane metalloendopeptidase like 1 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN protein processing (inferred); proteolysis (inferred); ASSOCIATED WITH primary biliary cholangitis (ortholog); rheumatoid arthritis (ortholog); FOUND IN endoplasmic reticulum (ortholog) ; extracellular space (ortholog); Golgi apparatus (ortholog) | 1 | 1323914 | 1362178 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12393478 | MMEL1 | membrane metalloendopeptidase like 1 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH primary biliary cholangitis (ortholog); rheumatoid arthritis (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog ); Golgi apparatus (ortholog) | 5 | 57434880 | 57467973 | Dog | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12539646 | Mmel1 | membrane metalloendopeptidase like 1 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN protein processing (inferred); proteolysis (inferred); ASSOCIATED WITH primary biliary cholangitis (ortholog); rheumatoid arthritis (ortholog); FOUND IN endoplasmic reticulum (ortholog) ; extracellular space (ortholog); Golgi apparatus (ortholog) | NW_004936737 | 970504 | 997452 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18918721 | Mmel1 | membrane metalloendopeptidase like 1 | ENCODES a protein that exhibits endopeptidase activity (ortholog); metalloendopeptidase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN protein processing (inferred); proteolysis (inferred); ASSOCIATED WITH primary biliary cholangitis (ortholog); rheumatoid arthritis (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog); Golgi apparatus (ortholog) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14272180 | MMEL1 | membrane metalloendopeptidase like 1 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH primary biliary cholangitis (ortholog); rheumatoid arthritis (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog ); Golgi apparatus (ortholog) | | | | Pig | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18579565 | MMEL1 | membrane metalloendopeptidase like 1 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN protein processing (inferred); proteolysis (inferred); ASSOCIATED WITH primary biliary cholangitis (ortholog); rheumatoid arthritis (ortholog); FOUND IN endoplasmic reticulum (ortholog) ; extracellular space (ortholog); Golgi apparatus (ortholog) | | | | Green Monkey | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626073077 | Mmel1 | membrane metalloendopeptidase like 1 | ENCODES a protein that exhibits endopeptidase activity (ortholog); metalloendopeptidase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN proteolysis (ortholog); ASSOCIATED WITH primary biliary cholangitis (ortholog); rheumatoid arthritis (ortholog); FOUND IN endoplasmic reticulum (ortho log); extracellular space (ortholog); Golgi apparatus (ortholog) | | | | Black Rat | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155254673 | mmel1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155256025 | mmel1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155254672 | mmel1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14700826 | MMEL1-AS1 | MMEL1 antisense RNA 1 | INTERACTS WITH dimethylselenide; hydroxyl | 1 | 2628756 | 2636620 | Human | 2 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 2301077 | Mmel1Tn(sb-T2/Bart3)2.255Mcwi | membrane metallo-endopeptidase-like 1; transposon insertion 2.255, Medical College of Wisconsin | this mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 1st intron of the Mmel1 gene | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |