| 71036 | Mepe | matrix extracellular phosphoglycoprotein | INVOLVED IN regulation of bone remodeling; negative regulation of bone mineralization (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 14 | 5725308 | 5736858 | Rat | 43 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 731927 | Mepe | matrix extracellular phosphoglycoprotein with ASARM motif (bone) | Predicted to enable extracellular matrix protein binding activity. Acts upstream of or within negative regulation of bone mineralization. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in several structures, including aorta; bone; connec tive tissue; lower jaw mesenchyme; and lower leg mesenchyme. Orthologous to human MEPE (matrix extracellular phosphoglycoprotein). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 104473195 | 104486477 | Mouse | 54 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 736255 | MEPE | matrix extracellular phosphoglycoprotein | This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a si milar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] | 4 | 87821398 | 87846792 | Human | 50 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 9062291 | Mepe | matrix extracellular phosphoglycoprotein | INVOLVED IN negative regulation of bone mineralization (ortholog); regulation of bone remodeling (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog) | NW_004955474 | 2048883 | 2064515 | Chinchilla | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11894392 | MEPE | matrix extracellular phosphoglycoprotein | ENCODES a protein that exhibits extracellular matrix protein binding (inferred); INVOLVED IN negative regulation of bone mineralization (ortholog); regulation of bone remodeling (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog); FOUND IN extracellular matrix (inferred) | 4 | 80125612 | 80139539 | Bonobo | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12394105 | MEPE | matrix extracellular phosphoglycoprotein | INVOLVED IN negative regulation of bone mineralization (ortholog); regulation of bone remodeling (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog) | 32 | 11212531 | 11222805 | Dog | 12 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12482104 | Mepe | matrix extracellular phosphoglycoprotein | ENCODES a protein that exhibits extracellular matrix protein binding (inferred); INVOLVED IN negative regulation of bone mineralization (ortholog); regulation of bone remodeling (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog); FOUND IN extracellular matrix (inferred) | NW_004936905 | 284849 | 297297 | Squirrel | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626164820 | Mepe | matrix extracellular phosphoglycoprotein | INVOLVED IN negative regulation of bone mineralization (ortholog); regulation of bone remodeling (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog) | | | | Black Rat | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18739517 | MEPE | matrix extracellular phosphoglycoprotein | ENCODES a protein that exhibits extracellular matrix protein binding (inferred); INVOLVED IN negative regulation of bone mineralization (ortholog); regulation of bone remodeling (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog); FOUND IN extracellular matrix (inferred) | | | | Green Monkey | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18927415 | Mepe | matrix extracellular phosphoglycoprotein | ENCODES a protein that exhibits extracellular matrix protein binding (inferred); INVOLVED IN negative regulation of bone mineralization (ortholog); regulation of bone remodeling (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog); FOUND IN extracellular matrix (inferred) | | | | Naked Mole-Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866034 | MEPE | matrix extracellular phosphoglycoprotein | | | | | Green Monkey | | symbol | gene, protein-coding |
| 14039964 | MEPE | matrix extracellular phosphoglycoprotein | INVOLVED IN negative regulation of bone mineralization (ortholog); regulation of bone remodeling (ortholog); ASSOCIATED WITH Bone Fractures (ortholog); osteomalacia (ortholog) | | | | Pig | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 629021559 | MEPE-AS1 | MEPE and IBSP antisense RNA 1 | | | | | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna |