| 1310296 | Med6 | mediator complex subunit 6 | ENCODES a protein that exhibits ubiquitin protein ligase activity; DNA binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN protein ubiquitination; positive regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATE S IN RNA polymerase II transcription pathway; FOUND IN ubiquitin ligase complex; mediator complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 6 | 107001664 | 107015130 | Rat | 80 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1321116 | MED6 | mediator complex subunit 6 | Enables transcription coactivator activity and transcription coactivator binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of core mediator complex and mediator complex. [provided by Alliance of Genome Resources, Jul 2025] | 14 | 70583221 | 70600655 | Human | 97 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1321117 | Med6 | mediator complex subunit 6 | Enables DNA binding activity. Acts upstream of or within somatic stem cell population maintenance. Located in nucleus. Part of mediator complex. Is expressed in brain; genitourinary system; limb; and tongue. Orthologous to human MED6 (mediator complex subunit 6) . [provided by Alliance of Genome Resources, Jul 2025] | 12 | 81620331 | 81641782 | Mouse | 97 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8713984 | Med6 | mediator complex subunit 6 | ENCODES a protein that exhibits DNA binding (ortholog); transcription coactivator activity (ortholog); transcription coactivator binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); stem cell population maintenance ( ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN mediator complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955523 | 4550348 | 4558806 | Chinchilla | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11726363 | MED6 | mediator complex subunit 6 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOU ND IN ubiquitin ligase complex (ortholog) | 14 | 51171280 | 51189026 | Bonobo | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12056852 | MED6 | mediator complex subunit 6 | ENCODES a protein that exhibits transcription coactivator binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); stem cell population maintenance (ortholog); PARTICIPATES I N RNA polymerase II transcription pathway; FOUND IN ubiquitin ligase complex (ortholog) | 8 | 44301449 | 44323554 | Dog | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625920469 | Med6 | mediator complex subunit 6 | ENCODES a protein that exhibits DNA binding (ortholog); transcription coactivator activity (ortholog); transcription coactivator binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); stem cell population maintenance ( ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN mediator complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14380565 | MED6 | | | | | | Fly | | symbol | gene, null |
| 18565752 | MED6 | mediator complex subunit 6 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOU ND IN ubiquitin ligase complex (ortholog) | | | | Green Monkey | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18920261 | Med6 | mediator complex subunit 6 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOU ND IN ubiquitin ligase complex (ortholog) | | | | Naked Mole-Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14380564 | MED6 | | | | | | Yeast | | symbol | gene, null |
| 13922132 | MED6 | mediator complex subunit 6 | ENCODES a protein that exhibits DNA binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II tr anscription pathway; FOUND IN ubiquitin ligase complex (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155243139 | med6 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155259023 | med6.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 12503543 | LOC101967362 | mediator of RNA polymerase II transcription subunit 6 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOU ND IN ubiquitin ligase complex (ortholog) | NW_004936488 | 195629 | 218762 | Squirrel | 40 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 7241615 | MED6P1 | mediator complex subunit 6 pseudogene 1 | | 10 | 88048151 | 88048656 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |