| 1306698 | Mcat | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (ortholog); RNA folding chaperone (ortholog); INVOLVED IN fatty acid biosynthetic process (ortholog); mitochondrial small ribosomal subunit assembly (ortholog); PARTICIPATES IN fatty acid biosynthetic pathway; ASSOC IATED WITH fundus dystrophy (ortholog); Optic Atrophy 15 (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; amphetamine | 7 | 116573632 | 116585767 | Rat | 73 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1315465 | Mcat | malonyl CoA:ACP acyltransferase (mitochondrial) | Predicted to enable [acyl-carrier-protein] S-malonyltransferase activity. Predicted to be involved in fatty acid biosynthetic process and mitochondrial small ribosomal subunit assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human MCAT tyle='font-weight:700;'>MCAT (malonyl-CoA-acyl carrier protein transacylase). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 83430998 | 83439936 | Mouse | 128 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1607045 | MCAT | malonyl-CoA-acyl carrier protein transacylase | The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and pl astid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012] | 22 | 43132206 | 43143398 | Human | 98 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8741632 | Mcat | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (ortholog); RNA folding chaperone (ortholog); INVOLVED IN fatty acid biosynthetic process (ortholog); mitochondrial small ribosomal subunit assembly (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog); Optic Atr ophy 15 (ortholog); FOUND IN mitochondrion (ortholog) | NW_004955413 | 28296507 | 28301669 | Chinchilla | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11908819 | MCAT | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (inferred); RNA folding chaperone (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred); ASS OCIATED WITH fundus dystrophy (ortholog); Optic Atrophy 15 (ortholog); FOUND IN mitochondrion (inferred) | 22 | 24016393 | 24026862 | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12230907 | MCAT | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (inferred); RNA folding chaperone (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred); ASS OCIATED WITH fundus dystrophy (ortholog); Optic Atrophy 15 (ortholog); FOUND IN mitochondrion (inferred) | 10 | 22404726 | 22414211 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12669821 | Mcat | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (inferred); RNA folding chaperone (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred); ASS OCIATED WITH fundus dystrophy (ortholog); Optic Atrophy 15 (ortholog); FOUND IN mitochondrion (inferred) | NW_004936718 | 970342 | 978836 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18390343 | MCAT | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (inferred); RNA folding chaperone (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred); ASS OCIATED WITH fundus dystrophy (ortholog); Optic Atrophy 15 (ortholog); FOUND IN mitochondrion (inferred) | | | | Green Monkey | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936326 | Mcat | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (ortholog); RNA folding chaperone (ortholog); INVOLVED IN mitochondrial small ribosomal subunit assembly (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog); Optic Atrophy 15 (ortholog); FOUND IN mitochondrion ( inferred) | | | | Naked Mole-Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625988272 | Mcat | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (ortholog); RNA folding chaperone (ortholog); INVOLVED IN fatty acid biosynthetic process (ortholog); mitochondrial small ribosomal subunit assembly (ortholog); ASSOCIATED WITH fundus dystrophy (ortholog); Optic Atr ophy 15 (ortholog); FOUND IN mitochondrion (ortholog) | | | | Black Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14047335 | MCAT | malonyl-CoA-acyl carrier protein transacylase | ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (inferred); RNA folding chaperone (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred); ASS OCIATED WITH fundus dystrophy (ortholog); Optic Atrophy 15 (ortholog); FOUND IN mitochondrion (inferred) | | | | Pig | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232900 | mcat | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155258313 | mcat.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155259674 | mcat.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 11316 | Slc7a1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | Enables L-amino acid transmembrane transporter activity and virus receptor activity. Involved in L-arginine transmembrane transport and L-ornithine transmembrane transport. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to be part of protein-containing c omplex. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; cranium; genitourinary system; immune system; and jaw. Orthologous to human SLC7A1 (solute carrier family 7 member 1). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 148264220 | 148336714 | Mouse | 281 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |