Mcat (malonyl-CoA-acyl carrier protein transacylase)

Gene: Mcat (malonyl-CoA-acyl carrier protein transacylase) Ictidomys tridecemlineatus

Analyze

Symbol:

Mcat

Name:

malonyl-CoA-acyl carrier protein transacylase

RGD ID:

12669821

Description:

ENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity (inferred); S-malonyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); monocarboxylic acid metabolic process (inferred); ASSOCIATED WITH Developmental Delay with Variable Intellectual Impairment and Behavioral Abnormalities (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

malonyl-CoA-acyl carrier protein transacylase, mitochondrial

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	6,001,319 - 6,009,823 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936718	970,339 - 978,851 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936718	970,342 - 978,836 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Developmental Delay with Variable Intellectual Impairment and Behavioral Abnormalities (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Optic Atrophy 15 (ISO)

Phelan-McDermid syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid biosynthetic process (IEA)

monocarboxylic acid metabolic process (IEA)

Cellular Component

mitochondrion (IEA)

Molecular Function

[acyl-carrier-protein] S-malonyltransferase activity (IEA)

S-malonyltransferase activity (IEA)

transferase activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Mcat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	6,001,319 - 6,009,823 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936718	970,339 - 978,851 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936718	970,342 - 978,836 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MCAT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	43,132,206 - 43,143,398 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	43,132,209 - 43,143,398 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	43,528,212 - 43,539,404 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	41,858,156 - 41,869,347 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	22	27,438,586 - 27,449,778 (-)	NCBI		Celera
Cytogenetic Map	22	q13.2	NCBI
HuRef	22	26,486,595 - 26,497,788 (-)	NCBI		HuRef
CHM1_1	22	43,487,793 - 43,498,986 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	22	43,613,358 - 43,624,552 (-)	NCBI		T2T-CHM13v2.0

Mcat
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	83,430,998 - 83,439,936 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	83,430,998 - 83,447,988 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	83,546,797 - 83,555,759 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	83,546,797 - 83,563,787 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	83,377,227 - 83,386,141 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	83,374,563 - 83,383,477 (-)	NCBI		MGSCv36	mm8
MGSCv36	15	84,341,152 - 84,350,066 (-)	NCBI		MGSCv36	mm8
Celera	15	85,648,411 - 85,681,449 (-)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI
cM Map	15	39.4	NCBI

Mcat
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	116,573,632 - 116,585,767 (-)	NCBI		GRCr8
mRatBN7.2	7	114,693,612 - 114,705,677 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	114,693,612 - 114,704,542 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	116,448,344 - 116,459,286 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	118,673,952 - 118,685,166 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	118,643,420 - 118,654,635 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	124,412,762 - 124,424,966 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	124,412,762 - 124,423,832 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	124,401,456 - 124,413,660 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	121,363,760 - 121,374,689 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	121,398,016 - 121,408,196 (+)	NCBI
Celera	7	111,006,726 - 111,017,653 (-)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

Mcat
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	28,296,964 - 28,301,722 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	28,296,507 - 28,301,669 (-)	NCBI	ChiLan1.0	ChiLan1.0

MCAT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	52,953,788 - 52,966,362 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	55,648,798 - 55,659,269 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	24,016,393 - 24,026,862 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	42,215,010 - 42,226,132 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	42,215,010 - 42,226,132 (-)	Ensembl	panpan1.1		panPan2

MCAT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	22,404,726 - 22,414,211 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	22,404,752 - 22,413,604 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	22,341,476 - 22,350,939 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	23,149,396 - 23,158,834 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	23,149,396 - 23,158,830 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	22,868,534 - 22,877,965 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	23,187,902 - 23,197,341 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	23,363,589 - 23,373,036 (+)	NCBI		UU_Cfam_GSD_1.0

MCAT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	5,742,185 - 5,751,456 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	5,742,190 - 5,750,193 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	3,164,821 - 3,172,828 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MCAT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	25,647,290 - 25,671,239 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	25,659,856 - 25,670,894 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	99,769,403 - 99,780,653 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mcat
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	5,827,956 - 5,836,400 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624752	5,828,037 - 5,836,896 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005338598	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000001357 ⟹ ENSSTOP00000001217

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936718	970,339 - 978,851 (-)	Ensembl

RefSeq Acc Id:

XM_005338598 ⟹ XP_005338655

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	6,001,319 - 6,009,823 (+)	NCBI
SpeTri2.0	NW_004936718	970,342 - 978,836 (-)	NCBI

Sequence:

show sequence

CACTGGGGCCTCAGTCGCCACGGTAACAGGCGCTGAGCAGGTGTGTCACCATGCGCGCCCGGGT
CGCGCGGGCCGCTTGGGCCTGGGGCTGCAGTGTCTGCTGCCGCCGCGGCGTCTCTAACTTCCCA
ATACCTCCGCCGAGCGCGGTGGACGTGGCAGAGCTGCTACGAGGCGCGACGACCGCGGAGGAGC
AGCCCTCGGCGGCGGCGGCGCGGCGAGCGCCCGGCCAGTGCTCGGTGCTGCTCTTCCCGGGCCA
GGGCAGCCAAGTGGTGGGCATGGGCCGCGGTCTGCTCGGCTACCCGCGCGTCCGCGAGCTCTAC
GACGCCGCGCAGCGCGTGCTGGGCTACGACCTGCTGGAGCTGAGCCTGCACGGGCCGCAGGAGG
ACCTGGACCGCACGGTGCACTGCCAGCCCGCTGTCTTCGTGGCTTCGCTGGCCGCTGTCGAGAA
GCTCCATCACCTGCAACCCGCGGTTATTGAAAATTGTATTGCTGCTGCTGGATTTAGTGTGGGA
GAATTTGCAGCCCTAGTGTTTGCTGGAGCTATGGAATTTTCTGAAGGTCTGTATGCAGTGAAAG
TTCGAGCTGAGGCCATGCAGGAAGCTTCAGAAGCTGTTCCCAGTGGGATGTTATCTGTCCTCGG
CCAGCCTCGGTCCAAGTTCAACTTTGCCTGTTTGGAAGCCCAGAAGCACTGCAAGTCATTGGGC
ATAGAGAGTCCTGTGTGTGAGGTGGCCAGCTATCTCTTTCCTGATTGCAGGGTGATTTCAGGAC
ACCTAGAGGCTCTGCGGTTTCTCCAGAAGAATTCCTCCAGGTACCACTTCAGACGCACCAAGAT
GCTGCCTGTGAGCGGCGGCTTCCACACCCGCCTCATGGAGCCCGCTGTGCAGCCCCTGGCACAG
GTTTTAAAGACAGTGGCCATCAGGAAGCCGCTGGTGGCCGTCTACTCTAACGTCAGTGGGAGCA
GGTACCTC

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Protein Sequences


Protein RefSeqs	XP_005338655	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000001217.3
GenBank Protein	KAG3290785	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005338655 ⟸ XM_005338598

- UniProtKB:

I3LYF6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRARVARAAWAWGCSVCCRRGVSNFPIPPPSAVDVAELLRGATTAEEQPSAAAARRAPGQCSVL
LFPGQGSQVVGMGRGLLGYPRVRELYDAAQRVLGYDLLELSLHGPQEDLDRTVHCQPAVFVASL
AAVEKLHHLQPAVIENCIAAAGFSVGEFAALVFAGAMEFSEGLYAVKVRAEAMQEASEAVPSGM
LSVLGQPRSKFNFACLEAQKHCKSLGIESPVCEVASYLFPDCRVISGHLEALRFLQKNSSRYHF
RRTKMLPVSGGFHTRLMEPAVQPLAQVLKTVAIRKPLVAVYSNVSGSRYL

hide sequence

RefSeq Acc Id:

ENSSTOP00000001217 ⟸ ENSSTOT00000001357

Protein Domains

Malonyl-CoA:ACP transacylase (MAT)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000001359	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000001357.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.366.10	UniProtKB/TrEMBL
	Malonyl-CoA ACP transacylase, ACP-binding	UniProtKB/TrEMBL
InterPro	Ac_transferase_dom_sf	UniProtKB/TrEMBL
	Acyl_transferase	UniProtKB/TrEMBL
	Acyl_Trfase/lysoPLipase	UniProtKB/TrEMBL
	Malonyl_transacylase_ACP-bd	UniProtKB/TrEMBL
NCBI Gene	Mcat	ENTREZGENE
PANTHER	[ACYL-CARRIER-PROTEIN] S-MALONYLTRANSFERASE	UniProtKB/TrEMBL
	MALONYL-COA ACP TRANSACYLASE, ACP-BINDING	UniProtKB/TrEMBL
Pfam	Acyl_transf_1	UniProtKB/TrEMBL
SMART	PKS_AT	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52151	UniProtKB/TrEMBL
	SSF55048	UniProtKB/TrEMBL
UniProt	I3LYF6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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