| 71079 | Lhx5 | LIM homeobox 5 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell proliferation in forebrain (ortholog); cell-cell signaling (ortholog); cerebellar Purkinje cell differentiation (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenz odioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 12 | 41786746 | 41795183 | Rat | 75 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 732692 | LHX5 | LIM homeobox 5 | This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In m ice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice. [provided by RefSeq, Jul 2008] | 12 | 113462033 | 113471871 | Human | 73 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 732693 | Lhx5 | LIM homeobox protein 5 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of DNA-templated transcription and spinal cord association neuron differentiation. A cts upstream of or within cerebellar Purkinje cell-granule cell precursor cell signaling; nervous system development; and regulation of neural precursor cell proliferation. Predicted to be active in nucleus. Is expressed in several structures, including future brain; limb; nervous system; sensory organ; and urinary system. Orthologous to human LHX5 (LIM homeobox 5). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 120569951 | 120579522 | Mouse | 100 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8792532 | Lhx5 | LIM homeobox 5 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell proliferation in forebrain (ortholog); cell-cell signaling (ortholog); cerebellar Purkinje cell differentiation (ortholog) | NW_004955482 | 9682671 | 9691155 | Chinchilla | 12 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11810066 | LHX5 | LIM homeobox 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN cell proliferation in forebrain (ortholog); cell-cell signaling (ortholog); cerebellar Purkinje cell differentiation (or tholog); FOUND IN nucleus (inferred) | 12 | 111063466 | 111075445 | Bonobo | 27 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12399760 | LHX5 | LIM homeobox 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN cell proliferation in forebrain (ortholog); cell-cell signaling (ortholog); cerebellar Purkinje cell differentiation (or tholog); FOUND IN nucleus (inferred) | 26 | 10776991 | 10785820 | Dog | 28 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12572544 | Lhx5 | LIM homeobox 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN cell proliferation in forebrain (ortholog); cell-cell signaling (ortholog); cerebellar Purkinje cell differentiation (or tholog); FOUND IN nucleus (inferred) | NW_004936668 | 3246456 | 3255353 | Squirrel | 28 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18390531 | LHX5 | LIM homeobox 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN cell proliferation in forebrain (ortholog); cell-cell signaling (ortholog); cerebellar Purkinje cell differentiation (or tholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 27 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626024588 | Lhx5 | LIM homeobox 5 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell proliferation in forebrain (ortholog); cell-cell signaling (ortholog); cerebellar Purkinje cell differentiation (ortholog) | | | | Black Rat | 12 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18930487 | Lhx5 | LIM homeobox 5 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell proliferation in forebrain (ortholog); cell-cell signaling (ortholog); cerebellar Purkinje cell differentiation (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 28 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155241329 | lhx5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14105000 | LHX5 | LIM homeobox 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN cell proliferation in forebrain (ortholog); cell-cell signaling (ortholog); cerebellar Purkinje cell differentiation (or tholog); FOUND IN nucleus (inferred) | | | | Pig | 28 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155241330 | lhx5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241931 | lhx5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 9588833 | LHX5-AS1 | LHX5 antisense RNA 1 | INTERACTS WITH acrylamide | 12 | 113472003 | 113480481 | Human | 1 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 402221714 | LOC134483945 | LIM/homeobox protein Lhx5-like | | 20 | 37972324 | 37976724 | Rat | | name | gene, protein-coding, MODEL [RefSeq] |
| 9642623 | Lhx5as1 | LIM homeobox 5, antisense 1 | Is expressed in telencephalon. [provided by Alliance of Genome Resources, Jul 2025] | 5 | 120557721 | 120569832 | Mouse | 5 | symbol , PhenoGen | gene, ncrna, VALIDATED [RefSeq] |