| 1309407 | Ing4 | inhibitor of growth family, member 4 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); INVOLVED IN DNA replication-dependent chromatin disassembly (ortholog); negative regulation of cell population prolife ration (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Lymphatic Metastasis (ortholog); prostate cancer (ortholog); FOUND IN histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil; amitrole | 4 | 159528183 | 159536762 | Rat | 134 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1319738 | ING4 | inhibitor of growth family member 4 | This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008] | 12 | 6650301 | 6663119 | Human | 126 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1319739 | Ing4 | inhibitor of growth family, member 4 | Predicted to enable methylated histone binding activity and transcription coactivator activity. Predicted to contribute to histone acetyltransferase activity. Involved in positive regulation of apoptotic process. Located in nucleus. Is expressed in several structures, including cerebral cortex; earl y conceptus; genitourinary system; sensory organ; and skeleton. Orthologous to human ING4 (inhibitor of growth family member 4). [provided by Alliance of Genome Resources, Apr 2025] | 6 | 125016811 | 125026228 | Mouse | 165 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8930253 | Ing4 | inhibitor of growth family member 4 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); INVOLVED IN DNA replication-dependent chromatin disassembly (ortholog); negative regulation of cell population prolife ration (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Lymphatic Metastasis (ortholog); prostate cancer (ortholog); FOUND IN histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955413 | 4263647 | 4274476 | Chinchilla | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11751731 | ING4 | inhibitor of growth family member 4 | ENCODES a protein that exhibits histone H4K16 acetyltransferase activity (ortholog); INVOLVED IN protein acetylation (ortholog); regulation of cell cycle G2/M phase transition (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Lymphatic Metastasis (ortholog); prostate cancer (ortholog); FO UND IN histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 12 | 6782402 | 6795035 | Bonobo | 48 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12274168 | ING4 | inhibitor of growth family member 4 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); INVOLVED IN DNA replication-dependent chromatin disassembly (ortholog); negative regulation of cell population prolife ration (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Lymphatic Metastasis (ortholog); prostate cancer (ortholog); FOUND IN histone acetyltransferase complex (ortholog); nucleoplasm (ortholog) | 27 | 38371656 | 38379251 | Dog | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12627083 | Ing4 | inhibitor of growth family member 4 | ENCODES a protein that exhibits histone H4K16 acetyltransferase activity (ortholog); INVOLVED IN protein acetylation (ortholog); regulation of cell cycle G2/M phase transition (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Lymphatic Metastasis (ortholog); prostate cancer (ortholog); FO UND IN histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936709 | 1140485 | 1147982 | Squirrel | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284371888 | ing4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625973575 | Ing4 | inhibitor of growth family member 4 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); INVOLVED IN DNA replication-dependent chromatin disassembly (ortholog); negative regulation of cell population prolife ration (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Lymphatic Metastasis (ortholog); prostate cancer (ortholog); FOUND IN histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18667867 | ING4 | inhibitor of growth family member 4 | ENCODES a protein that exhibits histone H4K16 acetyltransferase activity (ortholog); INVOLVED IN protein acetylation (ortholog); regulation of cell cycle G2/M phase transition (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Lymphatic Metastasis (ortholog); prostate cancer (ortholog); FO UND IN histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 47 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14005209 | ING4 | inhibitor of growth family member 4 | ENCODES a protein that exhibits histone H4K16 acetyltransferase activity (ortholog); INVOLVED IN protein acetylation (ortholog); regulation of cell cycle G2/M phase transition (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Lymphatic Metastasis (ortholog); prostate cancer (ortholog); FO UND IN histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922034 | Ing4 | inhibitor of growth family member 4 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); INVOLVED IN DNA replication-dependent chromatin disassembly (ortholog); negative regulation of cell population prolife ration (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Lymphatic Metastasis (ortholog); prostate cancer (ortholog); FOUND IN histone acetyltransferase complex (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 40 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 285485232 | ing4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 288083368 | ing4.S | | | | | | African Clawed Frog | | symbol | gene, null |