; ASSOCIATED WITH Craniosynostosis and Dental Anomalies (ortholog); Craniosynostosis Syndrome, Autosomal Recessive (ortholog); Heat Stroke (ortholog); FOUND IN extracellular region (inferred); membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran
Enables interleukin-11 binding activity and interleukin-11 receptor activity. Acts upstream of or within several processes, including cytokine-mediated signaling pathway; decidualization; and natural killer cell differentiation. Predicted to be located in extracellular region and membrane. Predicted
to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; immune system; and nervous system. Orthologous to human IL11RA (interleukin 11 receptor subunit alpha). [provided by Alliance of Genome Resources, Jul 2025]