| 1306201 | Igfbp7 | insulin-like growth factor binding protein 7 | ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN cellular response to hormone stimulus; cellular response to prostaglandin E stimulus; embryo implantation; ASSOCIATED WITH Burns; Experimental Liver Cirrhosis; metabolic dysfunction-associated steatotic liver disease; F OUND IN extracellular space; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 14 | 31091681 | 31151623 | Rat | 222 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1314683 | IGFBP7 | insulin like growth factor binding protein 7 | This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity , and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011] | 4 | 57030773 | 57110385 | Human | 243 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1314684 | Igfbp7 | insulin-like growth factor binding protein 7 | Predicted to enable insulin-like growth factor binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within inner ear development. Located in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, includin g alimentary system; brain; cardiovascular system; eye; and genitourinary system. Orthologous to human IGFBP7 (insulin like growth factor binding protein 7). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 77497092 | 77555892 | Mouse | 241 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8928438 | Igfbp7 | insulin like growth factor binding protein 7 | ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN angiogenesis (ortholog); cell adhesion (ortholog); cellular response to hormone stimulus (ortholog); ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); Burns (ortholog); FOUND IN extracellular space (ortholog) | NW_004955447 | 14048834 | 14110264 | Chinchilla | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11673612 | IGFBP7 | insulin like growth factor binding protein 7 | ENCODES a protein that exhibits growth factor binding (inferred); insulin-like growth factor binding (inferred); receptor ligand activity (inferred); INVOLVED IN cellular response to hormone stimulus (ortholog); cellular response to prostaglandin E stimulus (ortholog); embryo implantation (ortholog) ; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); Burns (ortholog); FOUND IN extracellular space (ortholog) | 4 | 66808845 | 66888301 | Bonobo | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12377502 | IGFBP7 | insulin like growth factor binding protein 7 | ENCODES a protein that exhibits growth factor binding (inferred); insulin-like growth factor binding (inferred); receptor ligand activity (inferred); INVOLVED IN cellular response to hormone stimulus (ortholog); cellular response to prostaglandin E stimulus (ortholog); embryo implantation (ortholog) ; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); Burns (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH masitinib | 13 | 49138406 | 49207235 | Dog | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12627498 | Igfbp7 | insulin like growth factor binding protein 7 | ENCODES a protein that exhibits growth factor binding (inferred); insulin-like growth factor binding (inferred); receptor ligand activity (inferred); INVOLVED IN cellular response to hormone stimulus (ortholog); cellular response to prostaglandin E stimulus (ortholog); embryo implantation (ortholog) ; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); Burns (ortholog); FOUND IN extracellular space (ortholog) | NW_004936482 | 19119339 | 19186679 | Squirrel | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626051452 | Igfbp7 | insulin like growth factor binding protein 7 | ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN angiogenesis (ortholog); cell adhesion (ortholog); cellular response to hormone stimulus (ortholog); ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); Burns (ortholog); FOUND IN extracellular space (ortholog) | | | | Black Rat | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866105 | IGFBP7 | insulin like growth factor binding protein 7 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 18672690 | IGFBP7 | insulin like growth factor binding protein 7 | ENCODES a protein that exhibits growth factor binding (inferred); insulin-like growth factor binding (inferred); receptor ligand activity (inferred); INVOLVED IN cellular response to hormone stimulus (ortholog); cellular response to prostaglandin E stimulus (ortholog); embryo implantation (ortholog) ; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); Burns (ortholog); FOUND IN extracellular space (ortholog) | | | | Green Monkey | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13876703 | IGFBP7 | insulin like growth factor binding protein 7 | ENCODES a protein that exhibits growth factor binding (inferred); insulin-like growth factor binding (inferred); receptor ligand activity (inferred); INVOLVED IN cellular response to hormone stimulus (ortholog); cellular response to prostaglandin E stimulus (ortholog); embryo implantation (ortholog) ; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); Burns (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 41 | symbol , old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18903168 | Igfbp7 | insulin like growth factor binding protein 7 | ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN angiogenesis (ortholog); cellular response to hormone stimulus (ortholog); cellular response to prostaglandin E stimulus (ortholog); ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); Burns (ortholog ); FOUND IN extracellular space (ortholog) | | | | Naked Mole-Rat | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 7361007 | IGFBP7-AS1 | IGFBP7 antisense RNA 1 | INTERACTS WITH cisplatin; triclosan | 4 | 57109762 | 57205299 | Human | 2 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |