| 1305614 | Igf2bp2 | insulin-like growth factor 2 mRNA binding protein 2 | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); mRNA 5'-UTR binding (ortholog); N6-methyladenosine-containing RNA reader activity (ortholog); INVOLVED IN cold-induced thermogenesis (ortholog); CRD-mediated mRNA stabilization (ortholog); energy homeostasis (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal dominant tubulointerstitial kidney disease 1 (ortholog); basal cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytoskeleton (ortholog); INTERACTS WITH 17beta-estradiol; atrazine; benzo[a]pyrene | 11 | 92378908 | 92478893 | Rat | 175 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 1606569 | IGF2BP2 | insulin like growth factor 2 mRNA binding protein 2 | This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016] | 3 | 185643130 | 185825042 | Human | 175 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1614069 | Igf2bp2 | insulin-like growth factor 2 mRNA binding protein 2 | Enables mRNA 3'-UTR binding activity; mRNA 5'-UTR binding activity; and translation regulator activity. Involved in negative regulation of translation. Acts upstream of or within cold-induced thermogenesis and energy homeostasis. Predicted to be located in P-body; cytoplasmic stress granule; and cyt oskeleton. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including adipose tissue; early conceptus; gonad; nervous system; and otocyst. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human IGF2BP2 (insulin like growth factor 2 mRNA binding protein 2). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 21877759 | 21982049 | Mouse | 207 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8720991 | Igf2bp2 | insulin like growth factor 2 mRNA binding protein 2 | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); mRNA 5'-UTR binding (ortholog); N6-methyladenosine-containing RNA reader activity (ortholog); INVOLVED IN cold-induced thermogenesis (ortholog); CRD-mediated mRNA stabilization (ortholog); energy homeostasis (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal dominant tubulointerstitial kidney disease 1 (ortholog); basal cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytoskeleton (ortholog) | NW_004955420 | 21818970 | 21957295 | Chinchilla | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11714102 | IGF2BP2 | insulin like growth factor 2 mRNA binding protein 2 | ENCODES a protein that exhibits translation regulator activity (ortholog); INVOLVED IN cold-induced thermogenesis (ortholog); energy homeostasis (ortholog); negative regulation of translation (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal dominant tubulointerstitial kidney disea se 1 (ortholog); basal cell carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytoskeleton (inferred) | 3 | 182667557 | 182848528 | Bonobo | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12367778 | IGF2BP2 | insulin like growth factor 2 mRNA binding protein 2 | ENCODES a protein that exhibits N6-methyladenosine-containing RNA reader activity (ortholog); translation regulator activity (ortholog); INVOLVED IN cold-induced thermogenesis (ortholog); energy homeostasis (ortholog); negative regulation of translation (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal dominant tubulointerstitial kidney disease 1 (ortholog); basal cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytoskeleton (ortholog); cytosol (ortholog) | 34 | 18368509 | 18522233 | Dog | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12542015 | Igf2bp2 | insulin like growth factor 2 mRNA binding protein 2 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN cold-induced thermogenesis (ortholog); energy homeostasis (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal domi nant tubulointerstitial kidney disease 1 (ortholog); basal cell carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytoskeleton (inferred) | NW_004936578 | 4070997 | 4222661 | Squirrel | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18902719 | Igf2bp2 | insulin like growth factor 2 mRNA binding protein 2 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN cold-induced thermogenesis (ortholog); energy homeostasis (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal domi nant tubulointerstitial kidney disease 1 (ortholog); basal cell carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytoskeleton (inferred) | | | | Naked Mole-Rat | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14068251 | IGF2BP2 | insulin like growth factor 2 mRNA binding protein 2 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN cold-induced thermogenesis (ortholog); energy homeostasis (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal domi nant tubulointerstitial kidney disease 1 (ortholog); basal cell carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytoskeleton (inferred) | | | | Pig | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18453743 | IGF2BP2 | insulin like growth factor 2 mRNA binding protein 2 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN cold-induced thermogenesis (ortholog); energy homeostasis (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal domi nant tubulointerstitial kidney disease 1 (ortholog); basal cell carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytoskeleton (inferred) | | | | Green Monkey | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626041343 | Igf2bp2 | insulin like growth factor 2 mRNA binding protein 2 | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); mRNA 5'-UTR binding (ortholog); N6-methyladenosine-containing RNA reader activity (ortholog); INVOLVED IN cold-induced thermogenesis (ortholog); CRD-mediated mRNA stabilization (ortholog); energy homeostasis (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal dominant tubulointerstitial kidney disease 1 (ortholog); basal cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytoskeleton (ortholog) | | | | Black Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1602599 | IGF2BP2-AS1 | IGF2BP2 antisense RNA 1 | INTERACTS WITH 2-hydroxypropanoic acid; DDE; propofol | 3 | 185713252 | 185729787 | Human | 4 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 38618806 | IGF2BP2P1 | IGF2BP2 pseudogene 1 | | 12 | 42286830 | 42290329 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38605834 | IGF2BP2P2 | IGF2BP2 pseudogene 2 | | 1 | 147050745 | 147054234 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38625026 | IGF2BP2P3 | IGF2BP2 pseudogene 3 | | 8 | 99231278 | 99234426 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16561396 | AC020629.1 | insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16553240 | AC244394.1 | insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16556583 | AP004290.1 | insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |