| 1309717 | Ift88 | intraflagellar transport 88 | ENCODES a protein that exhibits kinesin binding (ortholog); INVOLVED IN response to silicon dioxide; animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH silicosis; asphyxiating thoracic dystrophy (ort holog); autosomal recessive polycystic kidney disease (ortholog); FOUND IN outer acrosomal membrane; trans-Golgi network; acrosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 15 | 35685678 | 35786875 | Rat | 171 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1320207 | IFT88 | intraflagellar transport 88 | This gene encodes a member of the tetratrico peptide repeat (TPR) family. The encoded protein is involved in cilium biogenesis. Mutations of a similar gene in mouse can cause polycystic kidney disease. Several transcript variants encoding distinct isoforms have been identified for this gene. [provid ed by RefSeq, Jul 2017] | 13 | 20567157 | 20691444 | Human | 235 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1551338 | Ift88 | intraflagellar transport 88 | Enables kinesin binding activity. Involved in cilium assembly; regulation of autophagosome assembly; and regulation of cilium assembly. Acts upstream of or within several processes, including circulatory system development; cytoskeleton organization; and nervous system development. Located in severa l cellular components, including ciliary base; cytoskeleton; and non-motile cilium. Part of intraciliary transport particle B. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and respiratory system. Used to study autosomal recessive polycystic kidney disease; mitral valve disease; and scimitar syndrome. Orthologous to human IFT88 (intraflagellar transport 88). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 57661519 | 57755393 | Mouse | 365 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8845720 | Ift88 | intraflagellar transport 88 | ENCODES a protein that exhibits kinesin binding (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); brain development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); au tosomal recessive polycystic kidney disease (ortholog); basal cell carcinoma (ortholog); FOUND IN acrosomal membrane (ortholog); axonemal basal plate (ortholog); axoneme (ortholog) | NW_004955497 | 1338959 | 1454788 | Chinchilla | 122 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11946870 | IFT88 | intraflagellar transport 88 | ENCODES a protein that exhibits kinesin binding (inferred); INVOLVED IN animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); brain development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); au tosomal recessive polycystic kidney disease (ortholog); basal cell carcinoma (ortholog); FOUND IN acrosomal membrane (ortholog); axonemal basal plate (ortholog); axoneme (ortholog) | 13 | 1893102 | 2017771 | Bonobo | 130 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12287172 | IFT88 | intraflagellar transport 88 | INVOLVED IN animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); brain development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); autosomal recessive polycystic kidney disease (ortholog); basa l cell carcinoma (ortholog); FOUND IN acrosomal membrane (ortholog); axonemal basal plate (ortholog); axoneme (ortholog) | 25 | 17414965 | 17551405 | Dog | 132 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12583212 | Ift88 | intraflagellar transport 88 | ENCODES a protein that exhibits kinesin binding (inferred); INVOLVED IN animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); brain development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); au tosomal recessive polycystic kidney disease (ortholog); basal cell carcinoma (ortholog); FOUND IN acrosomal membrane (ortholog); axonemal basal plate (ortholog); axoneme (ortholog) | NW_004936720 | 1041216 | 1168725 | Squirrel | 130 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 329329063 | ift88 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18371860 | IFT88 | intraflagellar transport 88 | ENCODES a protein that exhibits kinesin binding (inferred); INVOLVED IN animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); brain development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); au tosomal recessive polycystic kidney disease (ortholog); basal cell carcinoma (ortholog); FOUND IN acrosomal membrane (ortholog); axonemal basal plate (ortholog); axoneme (ortholog) | | | | Green Monkey | 130 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625867491 | Ift88 | intraflagellar transport 88 | ENCODES a protein that exhibits kinesin binding (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); brain development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); au tosomal recessive polycystic kidney disease (ortholog); basal cell carcinoma (ortholog); FOUND IN acrosomal membrane (ortholog); axonemal basal plate (ortholog); axoneme (ortholog) | | | | Black Rat | 122 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18915102 | Ift88 | intraflagellar transport 88 | ENCODES a protein that exhibits kinesin binding (inferred); INVOLVED IN animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); brain development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); au tosomal recessive polycystic kidney disease (ortholog); basal cell carcinoma (ortholog); FOUND IN acrosomal membrane (ortholog); axonemal basal plate (ortholog); axoneme (ortholog) | | | | Naked Mole-Rat | 130 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13944055 | IFT88 | intraflagellar transport 88 | INVOLVED IN animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); brain development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); autosomal recessive polycystic kidney disease (ortholog); basa l cell carcinoma (ortholog); FOUND IN acrosomal membrane (ortholog); axonemal basal plate (ortholog); axoneme (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 133 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284854923 | ift88.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16568078 | AL590096.1 | novel transcript, antisense to IFT88 | | | | | Human | | name | gene, lncrna |
| 1611877 | Ift88os | intraflagellar transport 88, opposite strand | INTERACTS WITH 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl | | | | Mouse | 8 | symbol , old_gene_name , PhenoGen | gene, protein-coding |