| 1311005 | Hscb | HscB mitochondrial iron-sulfur cluster co-chaperone | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); iron-sulfur cluster assembly (ortholog); primitive erythrocyte differentiation (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATE D WITH sideroblastic anemia 5 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diuron | 12 | 51481318 | 51491689 | Rat | 75 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1322230 | Hscb | HscB iron-sulfur cluster co-chaperone | Predicted to enable identical protein binding activity. Involved in primitive erythrocyte differentiation. Located in mitochondrion. Human ortholog(s) of this gene implicated in sideroblastic anemia 5. Orthologous to human HSCB (HscB mitochondrial iron-sulfur cl uster cochaperone). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 110976945 | 110987647 | Mouse | 83 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1602295 | HSCB | HscB mitochondrial iron-sulfur cluster cochaperone | This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] | 22 | 28742032 | 28757510 | Human | 93 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8761853 | Hscb | HscB mitochondrial iron-sulfur cluster cochaperone | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); iron-sulfur cluster assembly (ortholog); primitive erythrocyte differentiation (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATE D WITH sideroblastic anemia 5 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog) | NW_004955455 | 3005617 | 3013393 | Chinchilla | 19 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12048083 | HSCB | HscB mitochondrial iron-sulfur cluster cochaperone | ENCODES a protein that exhibits ATPase activator activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN erythrocyte differentiation (ortholog); primitive erythrocyte differentiation (ortholog); primitive hemopoiesis (ortholog); PARTICIPATES IN mitochondr ial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH sideroblastic anemia 5 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred) | 22 | 9811294 | 9826245 | Bonobo | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12189248 | HSCB | HscB mitochondrial iron-sulfur cluster cochaperone | ENCODES a protein that exhibits ATPase activator activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN erythrocyte differentiation (ortholog); primitive erythrocyte differentiation (ortholog); primitive hemopoiesis (ortholog); PARTICIPATES IN mitochondr ial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH sideroblastic anemia 5 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred) | 26 | 22103803 | 22120200 | Dog | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12631985 | Hscb | HscB mitochondrial iron-sulfur cluster cochaperone | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); iron-sulfur cluster assembly (ortholog); primitive erythrocyte differentiation (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATE D WITH sideroblastic anemia 5 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog) | NW_004936657 | 2848282 | 2860115 | Squirrel | 19 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18902505 | Hscb | HscB mitochondrial iron-sulfur cluster cochaperone | ENCODES a protein that exhibits ATPase activator activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN erythrocyte differentiation (ortholog); primitive erythrocyte differentiation (ortholog); primitive hemopoiesis (ortholog); PARTICIPATES IN mitochondr ial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH sideroblastic anemia 5 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred) | | | | Naked Mole-Rat | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14258987 | HSCB | HscB mitochondrial iron-sulfur cluster cochaperone | ENCODES a protein that exhibits ATPase activator activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN erythrocyte differentiation (ortholog); primitive erythrocyte differentiation (ortholog); primitive hemopoiesis (ortholog); PARTICIPATES IN mitochondr ial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH sideroblastic anemia 5 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred) | | | | Pig | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18356385 | HSCB | HscB mitochondrial iron-sulfur cluster cochaperone | ENCODES a protein that exhibits ATPase activator activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN erythrocyte differentiation (ortholog); primitive erythrocyte differentiation (ortholog); primitive hemopoiesis (ortholog); PARTICIPATES IN mitochondr ial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH sideroblastic anemia 5 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred) | | | | Green Monkey | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155249974 | hscb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626022968 | Hscb | HscB mitochondrial iron-sulfur cluster cochaperone | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); iron-sulfur cluster assembly (ortholog); primitive erythrocyte differentiation (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATE D WITH sideroblastic anemia 5 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog) | | | | Black Rat | 19 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155233972 | hscb.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 12591206 | LOC101975974 | iron-sulfur cluster co-chaperone protein HscB-like | | NW_004936514 | 7761759 | 7762487 | Squirrel | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 18902060 | LOC101700419 | iron-sulfur cluster co-chaperone protein HscB, mitochondrial-like | ENCODES a protein that exhibits ATPase activator activity (inferred); protein-folding chaperone binding (inferred); INVOLVED IN [2Fe-2S] cluster assembly (inferred); protein complex oligomerization (inferred); FOUND IN cytoplasm (inferred); mitochondrion (inferred) | | | | Naked Mole-Rat | 8 | name | gene, protein-coding, MODEL [RefSeq] |
| 18920585 | LOC101708176 | iron-sulfur cluster co-chaperone protein HscB, mitochondrial pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18906388 | LOC101710898 | iron-sulfur cluster co-chaperone protein HscB, mitochondrial pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18901322 | LOC106008889 | iron-sulfur cluster co-chaperone protein HscB, mitochondrial pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18913661 | LOC106008976 | iron-sulfur cluster co-chaperone protein HscB, mitochondrial pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18905772 | LOC110348002 | iron-sulfur cluster co-chaperone protein HscB, mitochondrial pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 1601856 | EFCAB6 | EF-hand calcium binding domain 6 | This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenes is and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] | 22 | 43528778 | 43812305 | Human | 60 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |