| 1557635 | Hs6st2 | heparan sulfate 6-O-sulfotransferase 2 | Enables heparan sulfate 6-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Is active in Golgi apparatus. Is expressed in several structures, including brain; embryo mesenchyme; eye; foot bone; and genitourinary system. Human ortholog(s) of this gene implicate d in Paganini-Miozzo syndrome. Orthologous to human HS6ST2 (heparan sulfate 6-O-sulfotransferase 2). [provided by Alliance of Genome Resources, Jul 2025] | X | 50476084 | 50770643 | Mouse | 99 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564397 | Hs6st2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); PARTICIPATES IN heparan sulfate biosynthetic pathway; ASSOCIATED WITH Paganini-Miozzo syndrome (ortholog); FOUND IN Golgi apparatus (ortho log); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | X | 135887224 | 136182388 | Rat | 100 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1605906 | HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration. This gene encodes a member of the heparan sulfate (HS) sulfotransferase gen e family, which catalyze the transfer of sulfate to HS. Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | X | 132626015 | 132961370 | Human | 126 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 9047097 | Hs6st2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); ASSOCIATED WITH Paganini-Miozzo syndrome (ortholog); FOUND IN Golgi apparatus (ortholog) | NW_004955473 | 2002475 | 2291868 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12010702 | HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (inferred); sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); ASSOCIATED WITH Paganini-Miozzo syndrome (ortholog); FOUND IN Golgi apparatus (inferred); membrane (inferred) | X | 121757028 | 122090371 | Bonobo | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12171171 | HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (inferred); sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); ASSOCIATED WITH Paganini-Miozzo syndrome (ortholog); FOUND IN Golgi apparatus (inferred); membrane (inferred) | X | 103529705 | 103816049 | Dog | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12454877 | Hs6st2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (inferred); sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); ASSOCIATED WITH Paganini-Miozzo syndrome (ortholog); FOUND IN Golgi apparatus (inferred); membrane (inferred) | NW_004936691 | 1976449 | 2257303 | Squirrel | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18911386 | Hs6st2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (inferred); sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); ASSOCIATED WITH Paganini-Miozzo syndrome (ortholog); FOUND IN Golgi apparatus (ortholog) | | | | Naked Mole-Rat | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 286321901 | hs6st2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14182925 | HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (inferred); sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); ASSOCIATED WITH Paganini-Miozzo syndrome (ortholog); FOUND IN Golgi apparatus (inferred); membrane (inferred) | | | | Pig | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626034543 | Hs6st2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); ASSOCIATED WITH Paganini-Miozzo syndrome (ortholog); FOUND IN Golgi apparatus (ortholog) | | | | Black Rat | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18790968 | HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (ortholog); INVOLVED IN heparan sulfate proteoglycan biosynthetic process (ortholog); ASSOCIATED WITH Paganini-Miozzo syndrome (ortholog); FOUND IN Golgi apparatus (ortholog) | | | | Green Monkey | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866400 | HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | ENCODES a protein that exhibits heparan sulfate 6-sulfotransferase activity (inferred); sulfotransferase activity (inferred); transferase activity (inferred); FOUND IN Golgi apparatus (inferred); membrane (inferred) | | | | Green Monkey | 7 | symbol | gene, protein-coding |
| 405856573 | hs6st2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 628359456 | hs6st2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862149 | hs6st2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857597 | hs6st2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 628359527 | hs6st2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859917 | hs6st2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626469125 | hs6st2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856119 | hs6st2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863957 | hs6st2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468142 | hs6st2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859260 | hs6st2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468850 | hs6st2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405860436 | hs6st2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 6481307 | HS6ST2-AS1 | HS6ST2 antisense RNA 1 | | X | 132667642 | 132669888 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |