| 1307541 | Hipk4 | homeodomain interacting protein kinase 4 | ENCODES a protein that exhibits histone kinase activity (ortholog); protein kinase activity (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm ( ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 1 | 91938308 | 91948680 | Rat | 67 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1316795 | HIPK4 | homeodomain interacting protein kinase 4 | This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016] | 19 | 40379271 | 40390181 | Human | 69 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1621330 | Hipk4 | homeodomain interacting protein kinase 4 | Enables histone kinase activity. Acts upstream of or within peptidyl-serine phosphorylation; protein autophosphorylation; and regulation of signal transduction by p53 class mediator. Located in cytoplasm and nucleus. Is expressed in alimentary system; brain; and genitourinary system. Orthologous to human HIPK4 (homeodomain interacting protein kinase 4). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 27222686 | 27230605 | Mouse | 89 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8952791 | Hipk4 | homeodomain interacting protein kinase 4 | ENCODES a protein that exhibits histone kinase activity (ortholog); protein kinase activity (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm ( ortholog); nucleus (ortholog) | NW_004955578 | 876022 | 884098 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11978506 | HIPK4 | homeodomain interacting protein kinase 4 | ENCODES a protein that exhibits histone kinase activity (ortholog); protein kinase activity (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm ( ortholog); nucleus (ortholog) | 19 | 37427496 | 37439259 | Bonobo | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12384730 | HIPK4 | homeodomain interacting protein kinase 4 | ENCODES a protein that exhibits ATP binding (inferred); histone kinase activity (inferred); kinase activity (inferred); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUN D IN cytoplasm (inferred); nucleus (inferred) | 1 | 113297079 | 113304399 | Dog | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12552326 | Hipk4 | homeodomain interacting protein kinase 4 | ENCODES a protein that exhibits ATP binding (inferred); histone kinase activity (inferred); kinase activity (inferred); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUN D IN cytoplasm (inferred); nucleus (inferred) | NW_004936661 | 2764661 | 2770110 | Squirrel | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13954542 | HIPK4 | homeodomain interacting protein kinase 4 | ENCODES a protein that exhibits ATP binding (inferred); DNA binding (inferred); histone kinase activity (inferred); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Pig | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18910855 | Hipk4 | homeodomain interacting protein kinase 4 | ENCODES a protein that exhibits ATP binding (inferred); DNA binding (inferred); histone kinase activity (inferred); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625898507 | Hipk4 | homeodomain interacting protein kinase 4 | ENCODES a protein that exhibits histone kinase activity (ortholog); protein kinase activity (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm ( ortholog); nucleus (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18505812 | HIPK4 | homeodomain interacting protein kinase 4 | ENCODES a protein that exhibits ATP binding (inferred); histone kinase activity (inferred); kinase activity (inferred); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUN D IN cytoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |