| 1310134 | Gtf2e2 | general transcription factor IIE subunit 2 | ENCODES a protein that exhibits RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN RNA polymerase II preinitiation complex assembly (ortholog); transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; A SSOCIATED WITH genetic disease (ortholog); nonphotosensitive trichothiodystrophy 6 (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 16 | 65102386 | 65152563 | Rat | 85 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1320859 | GTF2E2 | general transcription factor IIE subunit 2 | The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by t his gene represents the beta subunit of TFIIE. [provided by RefSeq, Jan 2017] | 8 | 30578318 | 30658236 | Human | 190 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320860 | Gtf2e2 | general transcription factor II E, polypeptide 2 (beta subunit) | Predicted to enable RNA polymerase II general transcription initiation factor activity. Predicted to contribute to TFIIH-class transcription factor complex binding activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be located in cytosol and nuc leoplasm. Predicted to be part of transcription factor TFIID complex and transcription factor TFIIE complex. Is expressed in several structures, including blastocyst; central nervous system; foregut; genitourinary system; and liver lobe. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 6. Orthologous to human GTF2E2 (general transcription factor IIE subunit 2). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 34221942 | 34267201 | Mouse | 84 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9056842 | Gtf2e2 | general transcription factor IIE subunit 2 | ENCODES a protein that exhibits RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN RNA polymerase II preinitiation complex assembly (ortholog); transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; A SSOCIATED WITH genetic disease (ortholog); nonphotosensitive trichothiodystrophy 6 (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955463 | 7000868 | 7080778 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11944493 | GTF2E2 | general transcription factor IIE subunit 2 | ENCODES a protein that exhibits DNA binding (inferred); RNA polymerase II general transcription initiation factor activity (inferred); TFIIH-class transcription factor complex binding (inferred); INVOLVED IN DNA-templated transcription (inferred); RNA polymerase II preinitiation complex assembly (in ferred); transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH genetic disease (ortholog); nonphotosensitive trichothiodystrophy 6 (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred) | 8 | 29881879 | 29961554 | Bonobo | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12303458 | GTF2E2 | general transcription factor IIE subunit 2 | ENCODES a protein that exhibits DNA binding (inferred); RNA polymerase II general transcription initiation factor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); RNA polymerase II preinitiation complex assembly (inferred); transcription by RNA polymerase II (inferred); PARTI CIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH genetic disease (ortholog); nonphotosensitive trichothiodystrophy 6 (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred) | 16 | 33697872 | 33778247 | Dog | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12692925 | Gtf2e2 | general transcription factor IIE subunit 2 | ENCODES a protein that exhibits DNA binding (inferred); RNA polymerase II general transcription initiation factor activity (inferred); TFIIH-class transcription factor complex binding (inferred); INVOLVED IN DNA-templated transcription (inferred); RNA polymerase II preinitiation complex assembly (in ferred); transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH genetic disease (ortholog); nonphotosensitive trichothiodystrophy 6 (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936792 | 409637 | 484010 | Squirrel | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155260170 | gtf2e2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625860317 | Gtf2e2 | general transcription factor IIE subunit 2 | ENCODES a protein that exhibits RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN RNA polymerase II preinitiation complex assembly (ortholog); transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; A SSOCIATED WITH genetic disease (ortholog); nonphotosensitive trichothiodystrophy 6 (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14145205 | GTF2E2 | general transcription factor IIE subunit 2 | ENCODES a protein that exhibits DNA binding (inferred); RNA polymerase II general transcription initiation factor activity (inferred); translation initiation factor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); RNA polymerase II preinitiation complex assembly (inferred); t ranscription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH genetic disease (ortholog); nonphotosensitive trichothiodystrophy 6 (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 33 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18337501 | GTF2E2 | general transcription factor IIE subunit 2 | ENCODES a protein that exhibits RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN RNA polymerase II preinitiation complex assembly (ortholog); transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; A SSOCIATED WITH genetic disease (ortholog); nonphotosensitive trichothiodystrophy 6 (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921243 | Gtf2e2 | general transcription factor IIE subunit 2 | ENCODES a protein that exhibits RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN RNA polymerase II preinitiation complex assembly (ortholog); transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; A SSOCIATED WITH genetic disease (ortholog); nonphotosensitive trichothiodystrophy 6 (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); transcription factor TFIID complex (ortholog) | | | | Naked Mole-Rat | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257670 | gtf2e2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 16565979 | AL590229.2 | general transcription factor IIE, polypeptide 2, beta 34kDa (GTF2E2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |