| 1303027 | C5ar2 | complement C5a receptor 2 | ENCODES a protein that exhibits complement receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of interleukin-6 production (ortholog); negative regulation of neutrophil chemotaxis (ortholog); negative regulation of tumor necrosis factor produ ction (ortholog); FOUND IN apical part of cell (ortholog); basal plasma membrane (ortholog); INTERACTS WITH (R)-noradrenaline; 17beta-estradiol; 17beta-estradiol 3-benzoate | 1 | 86058557 | 86073583 | Rat | 101 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1354173 | C5AR2 | complement C5a receptor 2 | This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] | 19 | 47332175 | 47347329 | Human | 91 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1616450 | C5ar2 | complement component 5a receptor 2 | Predicted to enable G protein-coupled receptor activity and complement component C5a receptor activity. Predicted to be involved in several processes, including complement receptor mediated signaling pathway; negative regulation of neutrophil chemotaxis; and regulation of cytokine production. Predic ted to be located in apical part of cell and basal plasma membrane. Predicted to be active in plasma membrane. Orthologous to human C5AR2 (complement C5a receptor 2). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 15968512 | 15978079 | Mouse | 112 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12035277 | C5AR2 | complement C5a receptor 2 | ENCODES a protein that exhibits complement component C5a receptor activity (inferred); complement receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN chemotaxis (inferred); complement component C5a signaling pathway (inferred); complement receptor mediated signa ling pathway (inferred); FOUND IN apical part of cell (inferred); basal plasma membrane (inferred); membrane (inferred) | 19 | 44320315 | 44331732 | Bonobo | 27 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12323288 | C5AR2 | complement C5a receptor 2 | ENCODES a protein that exhibits complement receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN chemotaxis (inferred); complement component C5a signaling pathway (inferred); complement receptor mediated signaling pathway (inferred); FOUND IN apical part of cell ( inferred); basal plasma membrane (inferred); membrane (inferred); INTERACTS WITH bisphenol A | 1 | 108644195 | 108652628 | Dog | 29 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |