| 1311832 | Gpr65 | G-protein coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cellular response to acidic pH (ortholog); G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH ulcera tive colitis (ortholog); FOUND IN early endosome membrane (ortholog); late endosome membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH acetamide; alpha-Zearalanol; bisphenol A | 6 | 123245534 | 123262758 | Rat | 95 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1323495 | GPR65 | G protein-coupled receptor 65 | Enables G protein-coupled receptor activity. Involved in several processes, including activation of GTPase activity; positive regulation of stress fiber assembly; and response to acidic pH. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025] | 14 | 88005135 | 88014811 | Human | 89 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1323496 | Gpr65 | G-protein coupled receptor 65 | Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including activation of GTPase activity; positive regulation of stress fiber assembly; and response to acidic pH. Predicted to be active in plasma membrane. Is expressed in several structures, inc luding alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human GPR65 (G protein-coupled receptor 65). [provided by Alliance of Genome Resources, Apr 2025] | 12 | 98234894 | 98242981 | Mouse | 104 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9044945 | Gpr65 | G protein-coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cellular response to acidic pH (ortholog); G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH ulcera tive colitis (ortholog); FOUND IN early endosome membrane (ortholog); late endosome membrane (ortholog); plasma membrane (ortholog) | NW_004955438 | 10724069 | 10730868 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11850475 | GPR65 | G protein-coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN positive regulation of interleukin-22 production (ortholog); positive regulation of T-helper cell differentiation (ortholog); ASSOCIATED WITH ulcerative colitis (ortholog); FOUND IN plasma membrane (ortholog) | 14 | 68617219 | 68624158 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12211957 | GPR65 | G protein-coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cellular response to acidic pH (ortholog); positive regulation of interleukin-22 production (ortholog); ASSOCIATED WITH ul cerative colitis (ortholog); FOUND IN early endosome membrane (ortholog); late endosome membrane (ortholog); plasma membrane (ortholog) | 8 | 59334544 | 59351039 | Dog | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12484206 | Gpr65 | G protein-coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN positive regulation of interleukin-22 production (ortholog); positive regulation of T-helper cell differentiation (ortholog); ASSOCIATED WITH ulcerative colitis (ortholog); FOUND IN plasma membrane (ortholog) | NW_004936488 | 15544075 | 15545344 | Squirrel | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284564078 | gpr65 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625844456 | Gpr65 | G protein-coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cellular response to acidic pH (ortholog); G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH ulcera tive colitis (ortholog); FOUND IN early endosome membrane (ortholog); late endosome membrane (ortholog); plasma membrane (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18589823 | GPR65 | G protein-coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN positive regulation of interleukin-22 production (ortholog); positive regulation of T-helper cell differentiation (ortholog); ASSOCIATED WITH ulcerative colitis (ortholog); FOUND IN plasma membrane (ortholog) | | | | Green Monkey | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14229838 | GPR65 | G protein-coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN positive regulation of interleukin-22 production (ortholog); positive regulation of T-helper cell differentiation (ortholog); ASSOCIATED WITH ulcerative colitis (ortholog); FOUND IN plasma membrane (ortholog) | | | | Pig | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936794 | Gpr65 | G protein-coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN positive regulation of interleukin-22 production (ortholog); positive regulation of T-helper cell differentiation (ortholog); ASSOCIATED WITH ulcerative colitis (ortholog); FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 150657656 | GPR65 | G protein-coupled receptor 65 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (inferred); cellular response to acidic pH (inferred); G protein-coupled receptor signaling pathway (inferred); FOUND IN early endosom e membrane (inferred); late endosome membrane (inferred); membrane (inferred) | | | | Dog | 16 | symbol | gene, protein-coding |
| 284562787 | gpr65.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 286819469 | gpr65.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16561651 | AL157955.1 | novel transcript, antisense to GPR65 | | | | | Human | | name | gene, lncrna |