| 1311729 | Gpr139 | G protein-coupled receptor 139 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); identical protein binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathwa y (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 1 | 182909476 | 182953942 | Rat | 34 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1323337 | GPR139 | G protein-coupled receptor 139 | This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple t ranscript variants. [provided by RefSeq, Jan 2016] | 16 | 20028239 | 20073890 | Human | 30 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1620635 | Gpr139 | G protein-coupled receptor 139 | Enables identical protein binding activity and neuropeptide receptor activity. Involved in G protein-coupled receptor signaling pathway. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Is expressed in seve ral structures, including ileum; liver; male reproductive gland or organ; nervous system; and spleen. Orthologous to human GPR139 (G protein-coupled receptor 139). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 118739970 | 118783761 | Mouse | 37 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9035341 | Gpr139 | G protein-coupled receptor 139 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); identical protein binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathwa y (ortholog) | NW_004955442 | 3698546 | 3737281 | Chinchilla | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11787481 | GPR139 | G protein-coupled receptor 139 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); identical protein binding (inferred); neuropeptide receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathwa y (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 16 | 18238117 | 18283773 | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12405684 | GPR139 | G protein-coupled receptor 139 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); identical protein binding (inferred); neuropeptide receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathwa y (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 6 | 25249898 | 25293044 | Dog | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12491498 | Gpr139 | G protein-coupled receptor 139 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); identical protein binding (inferred); neuropeptide receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathwa y (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936501 | 5585278 | 5620667 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929556 | Gpr139 | G protein-coupled receptor 139 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathway (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288083311 | gpr139 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18667921 | GPR139 | G protein-coupled receptor 139 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); identical protein binding (inferred); neuropeptide receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathwa y (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14122692 | GPR139 | G protein-coupled receptor 139 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); identical protein binding (inferred); neuropeptide receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathwa y (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625862158 | Gpr139 | G protein-coupled receptor 139 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); identical protein binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathwa y (ortholog) | | | | Black Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 405861205 | gpr139.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626182539 | gpr139.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856839 | gpr139.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626170898 | gpr139.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863249 | gpr139.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863742 | gpr139.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626177897 | gpr139.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284981287 | gpr139.S | | | | | | African Clawed Frog | | symbol | gene, null |
