| 620179 | Gnpat | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits catalytic activity (ortholog); glycerone-phosphate O-acyltransferase activity (ortholog); INVOLVED IN response to fatty acid; response to nutrient; response to starvation; PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; glycerophosphol ipid metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane; peroxisome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-methoxyethanol | 19 | 69719707 | 69746244 | Rat | 123 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 733936 | GNPAT | glyceronephosphate O-acyltransferase | This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] | 1 | 231241212 | 231277973 | Human | 237 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 733937 | Gnpat | glyceronephosphate O-acyltransferase | Enables glycerone-phosphate O-acyltransferase activity. Acts upstream of or within several processes, including cell junction assembly; cerebellum morphogenesis; and ether lipid biosynthetic process. Located in peroxisome. Is expressed in several structures, including alimentary system; genitourinar y system; nervous system; respiratory system; and sensory organ. Used to study disease of mental health and rhizomelic chondrodysplasia punctata type 2. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata type 2. Orthologous to human GNPAT (glyceronephosphate O-acyltransferase). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 125589772 | 125616796 | Mouse | 162 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9051097 | Gnpat | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits catalytic activity (ortholog); glycerone-phosphate O-acyltransferase activity (ortholog); INVOLVED IN cerebellum morphogenesis (ortholog); ether lipid biosynthetic process (ortholog); membrane organization (ortholog); PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane (ortholog); peroxisome (ortholog) | NW_004955492 | 7489080 | 7519590 | Chinchilla | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11783616 | GNPAT | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits acyltransferase activity (inferred); catalytic activity (inferred); glycerol-3-phosphate O-acyltransferase activity (inferred); INVOLVED IN cerebellum morphogenesis (ortholog); ether lipid biosynthetic process (ortholog); membrane organization (ortholog); PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN mitochondrial membrane (inferred); peroxisomal membrane (inferred); peroxisome (inferred) | 1 | 206794245 | 206830840 | Bonobo | 48 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12072655 | GNPAT | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits acyltransferase activity (inferred); catalytic activity (inferred); glycerone-phosphate O-acyltransferase activity (inferred); INVOLVED IN cerebellum morphogenesis (ortholog); ether lipid biosynthetic process (ortholog); membrane organization (ortholog); PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane (inferred); peroxisome (inferred) | 4 | 8155186 | 8190403 | Dog | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12712964 | Gnpat | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits acyltransferase activity (inferred); catalytic activity (inferred); glycerol-3-phosphate O-acyltransferase activity (inferred); INVOLVED IN cerebellum morphogenesis (ortholog); ether lipid biosynthetic process (ortholog); membrane organization (ortholog); PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN mitochondrial membrane (inferred); peroxisomal membrane (inferred); peroxisome (inferred) | NW_004936484 | 19414094 | 19434929 | Squirrel | 48 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18504205 | GNPAT | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits acyltransferase activity (inferred); catalytic activity (inferred); glycerol-3-phosphate O-acyltransferase activity (inferred); INVOLVED IN cerebellum morphogenesis (ortholog); ether lipid biosynthetic process (ortholog); membrane organization (ortholog); PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN mitochondrial membrane (inferred); peroxisomal membrane (inferred); peroxisome (inferred) | | | | Green Monkey | 48 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626119472 | Gnpat | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits catalytic activity (ortholog); glycerone-phosphate O-acyltransferase activity (ortholog); INVOLVED IN cerebellum morphogenesis (ortholog); ether lipid biosynthetic process (ortholog); membrane organization (ortholog); PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane (ortholog); peroxisome (ortholog) | | | | Black Rat | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929236 | Gnpat | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits catalytic activity (ortholog); INVOLVED IN cerebellum morphogenesis (ortholog); ether lipid biosynthetic process (ortholog); membrane organization (ortholog); PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; ASSOCIATED WITH Desbuquois d ysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN mitochondrial membrane (inferred); peroxisomal membrane (inferred); peroxisome (inferred) | | | | Naked Mole-Rat | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14093594 | GNPAT | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits acyltransferase activity (inferred); catalytic activity (inferred); glycerone-phosphate O-acyltransferase activity (inferred); INVOLVED IN cerebellum morphogenesis (ortholog); ether lipid biosynthetic process (ortholog); membrane organization (ortholog); PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane (inferred); peroxisome (inferred) | | | | Pig | 43 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155256621 | gnpat | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 405856781 | gnpat.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856898 | gnpat.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858433 | gnpat.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405860076 | gnpat.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626178271 | gnpat.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247804 | gnpat.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 2291823 | GNPATP | glyceronephosphate O-acyltransferase pseudogene | | 16 | 60654071 | 60655974 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |