| 1346519 | GNL3L | G protein nucleolar 3 like | The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010] | X | 54530219 | 54645854 | Human | 115 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1600217 | Gnl3l | G protein nucleolar 3 like | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); INVOLVED IN negative regulation of protein sumoylation (ortholog); negative regulation of protein ubiquitination (ortholog); negative regulation of telomere maintenance via telomerase (ortholog); PARTICIPATES IN r ibosome biogenesis pathway; FOUND IN nucleolus (ortholog); telomerase holoenzyme complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | X | 23404324 | 23437501 | Rat | 111 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1619824 | Gnl3l | guanine nucleotide binding protein nucleolar 3 like | Predicted to enable GTP binding activity. Predicted to be involved in several processes, including negative regulation of protein modification by small protein conjugation or removal; negative regulation of telomere maintenance via telomerase; and positive regulation of protein localization to chrom osome, telomeric region. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of telomerase holoenzyme complex. Predicted to be active in nucleolus. Orthologous to human GNL3L (G protein nucleolar 3 like). [provided by Alliance of Genome Resources, Jul 2025] | X | 149766129 | 149800318 | Mouse | 122 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8860313 | Gnl3l | G protein nucleolar 3 like | INVOLVED IN negative regulation of protein sumoylation (ortholog); negative regulation of protein ubiquitination (ortholog); negative regulation of telomere maintenance via telomerase (ortholog); FOUND IN nucleolus (ortholog); telomerase holoenzyme complex (ortholog) | NW_004955475 | 1792268 | 1849601 | Chinchilla | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11981359 | GNL3L | G protein nucleolar 3 like | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); INVOLVED IN negative regulation of protein sumoylation (inferred); negative regulation of protein ubiquitination (inferred); negative regulation of telomere maintenance via telomerase (inferred); FOUND IN nucleolu s (inferred); nucleus (inferred); telomerase holoenzyme complex (inferred) | X | 46733431 | 46825139 | Bonobo | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12427911 | GNL3L | G protein nucleolar 3 like | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); INVOLVED IN negative regulation of protein sumoylation (inferred); negative regulation of protein ubiquitination (inferred); negative regulation of telomere maintenance via telomerase (inferred); FOUND IN nucleolu s (inferred); nucleus (inferred); telomerase holoenzyme complex (inferred) | X | 46270162 | 46296972 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12601221 | Gnl3l | G protein nucleolar 3 like | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); INVOLVED IN negative regulation of protein sumoylation (inferred); negative regulation of protein ubiquitination (inferred); negative regulation of telomere maintenance via telomerase (inferred); FOUND IN nucleolu s (inferred); nucleus (inferred); telomerase holoenzyme complex (inferred) | NW_004936751 | 1423822 | 1457257 | Squirrel | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155243303 | gnl3l | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18434112 | GNL3L | G protein nucleolar 3 like | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); INVOLVED IN negative regulation of protein sumoylation (inferred); negative regulation of protein ubiquitination (inferred); negative regulation of telomere maintenance via telomerase (inferred); FOUND IN nucleolu s (inferred); nucleus (inferred); telomerase holoenzyme complex (inferred) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14086503 | GNL3L | G protein nucleolar 3 like | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); INVOLVED IN negative regulation of protein sumoylation (inferred); negative regulation of protein ubiquitination (inferred); negative regulation of telomere maintenance via telomerase (inferred); FOUND IN nucleolu s (inferred); nucleus (inferred); telomerase holoenzyme complex (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625875934 | Gnl3l | G protein nucleolar 3 like | INVOLVED IN negative regulation of protein sumoylation (ortholog); negative regulation of protein ubiquitination (ortholog); negative regulation of telomere maintenance via telomerase (ortholog); FOUND IN nucleolus (ortholog); telomerase holoenzyme complex (ortholog) | | | | Black Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18925051 | Gnl3l | G protein nucleolar 3 like | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); INVOLVED IN negative regulation of protein sumoylation (ortholog); negative regulation of protein ubiquitination (ortholog); negative regulation of telomere maintenance via telomerase (ortholog); FOUND IN telomera se holoenzyme complex (ortholog) | | | | Naked Mole-Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155253007 | gnl3l.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1605036 | GNL3LP1 | G protein nucleolar 3 like pseudogene 1 | INTERACTS WITH disodium selenite; dorsomorphin; lipopolysaccharide | 5 | 60891676 | 60893662 | Human | 9 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 12176776 | TSR2 | TSR2 ribosome maturation factor | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); INVOLVED IN negative regulation of protein sumoylation (inferred); negative regulation of protein ubiquitination (inferred); negative regulation of telomere maintenance via telomerase (inferred); ASSOCIATED WITH D iamond-Blackfan anemia 14 with mandibulofacial dysostosis (ortholog); Diamond-Blackfan anemia 15 with mandibulofacial dysostosis (ortholog); FOUND IN nucleolus (inferred); nucleus (inferred); telomerase holoenzyme complex (inferred) | X | 46189810 | 46194949 | Dog | 21 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |