Fzd6 Gene Search Result

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

Genes search result for All species
(View Results for all Objects and Ontologies)

18 records found for search term Fzd6

Refine Term:

Sort By:

Export

RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
628816	Fzd6	frizzled class receptor 6	ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); Wnt receptor activity (ortholog); Wnt-protein binding (ortholog); INVOLVED IN cell proliferation in midbrain (ortholog); embryonic nail plate morphogenesis (ortholog); establishment of body hair planar orientation (ortholog ... (more) ); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canonical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); Hydrops Fetalis (ortholog); nail disease (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); apicolateral plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1	7	71939916	71971685	Rat	181	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1343855	FZD6	frizzled class receptor 6	This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven trans ... (more) membrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]	8	103298494	103332866	Human	194	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1550465	Fzd6	frizzled class receptor 6	Enables Wnt-protein binding activity. Acts upstream of or within several processes, including cell proliferation in midbrain; embryonic morphogenesis; and establishment of body hair planar orientation. Located in apical plasma membrane; apicolateral plasma membrane; and endoplasmic reticulum membran ... (more) e. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 1. Orthologous to human FZD6 (frizzled class receptor 6). [provided by Alliance of Genome Resources, Jul 2025]	15	38869673	38901587	Mouse	200	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8728559	Fzd6	frizzled class receptor 6	ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); Wnt receptor activity (ortholog); Wnt-protein binding (ortholog); INVOLVED IN cell proliferation in midbrain (ortholog); embryonic nail plate morphogenesis (ortholog); establishment of body hair planar orientation (ortholog ... (more) ); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canonical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); Hydrops Fetalis (ortholog); nail disease (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); apicolateral plasma membrane (ortholog)	NW_004955417	27465730	27493752	Chinchilla	38	symbol	gene, protein-coding, MODEL [RefSeq]
11870512	FZD6	frizzled class receptor 6	ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN cell proliferation in midbrain (ortholog); embryonic nail plate morphogenesis (ortholog); establishment of bo ... (more) dy hair planar orientation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canonical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); Hydrops Fetalis (ortholog); nail disease (ortholog); FOUND IN apical part of cell (inferred); apical plasma membrane (inferred); apicolateral plasma membrane (inferred)	8	99954523	99989153	Bonobo	55	symbol	gene, protein-coding, MODEL [RefSeq]
12321590	FZD6	frizzled class receptor 6	ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN cell proliferation in midbrain (ortholog); embryonic nail plate morphogenesis (ortholog); establishment of bo ... (more) dy hair planar orientation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canonical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); Hydrops Fetalis (ortholog); nail disease (ortholog); FOUND IN plasma membrane; endoplasmic reticulum membrane (ortholog); INTERACTS WITH bisphenol A	13	4732541	4771294	Dog	59	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
12492401	Fzd6	frizzled class receptor 6	ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN cell proliferation in midbrain (ortholog); embryonic nail plate morphogenesis (ortholog); establishment of bo ... (more) dy hair planar orientation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canonical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); Hydrops Fetalis (ortholog); nail disease (ortholog); FOUND IN apical part of cell (inferred); apical plasma membrane (inferred); apicolateral plasma membrane (inferred)	NW_004936470	40416254	40454717	Squirrel	58	symbol	gene, protein-coding, MODEL [RefSeq]
18920443	Fzd6	frizzled class receptor 6	ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN cell proliferation in midbrain (ortholog); embryonic nail plate morphogenesis (ortholog); establishment of body hair planar orientation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canon ... (more) ical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); Hydrops Fetalis (ortholog); nail disease (ortholog); FOUND IN apical part of cell (ortholog); apicolateral plasma membrane (ortholog)				Naked Mole-Rat	52	symbol	gene, protein-coding, MODEL [RefSeq]
18636016	FZD6	frizzled class receptor 6	ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN cell proliferation in midbrain (ortholog); embryonic nail plate morphogenesis (ortholog); establishment of bo ... (more) dy hair planar orientation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canonical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); Hydrops Fetalis (ortholog); nail disease (ortholog); FOUND IN apical part of cell (inferred); apical plasma membrane (inferred); apicolateral plasma membrane (inferred)				Green Monkey	55	symbol	gene, protein-coding, MODEL [RefSeq]
13897600	FZD6	frizzled class receptor 6	ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN cell proliferation in midbrain (ortholog); embryonic nail plate morphogenesis (ortholog); establishment of bo ... (more) dy hair planar orientation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canonical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); Hydrops Fetalis (ortholog); nail disease (ortholog); FOUND IN apical part of cell (inferred); apical plasma membrane (inferred); apicolateral plasma membrane (inferred)				Pig	53	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
152177996	FZD6	frizzled class receptor 6					Naked Mole-Rat		symbol	gene, protein-coding
625960047	Fzd6	frizzled class receptor 6	ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); Wnt receptor activity (ortholog); Wnt-protein binding (ortholog); INVOLVED IN cell proliferation in midbrain (ortholog); embryonic nail plate morphogenesis (ortholog); establishment of body hair planar orientation (ortholog ... (more) ); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canonical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH genetic disease (ortholog); Hydrops Fetalis (ortholog); nail disease (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); apicolateral plasma membrane (ortholog)				Black Rat	38	symbol	gene, protein-coding, MODEL [RefSeq]
155249910	fzd6						Tropical Clawed Frog		symbol	gene, null
155258647	fzd6.L						African Clawed Frog		symbol	gene, null
155247709	fzd6.S						African Clawed Frog		symbol	gene, null
8655302	BAALC-AS1	BAALC antisense RNA 1		8	103243538	103298818	Human		old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]
36947644	BAALC-AS1	BAALC antisense RNA 1	INTERACTS WITH aristolochic acid A; cadmium dichloride; sodium arsenite	8	103156990	103172140	Human	3	old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]
16571454	AC025370.2	novel transcript, antisense to FZD6					Human		name	gene, lncrna