| 1308669 | Foxp1 | forkhead box P1 | ENCODES a protein that exhibits transcription cis-regulatory region binding; transcription factor binding; chromatin binding (ortholog); INVOLVED IN cellular response to ionomycin; cellular response to tumor necrosis factor; forebrain development; ASSOCIATED WITH Brain Injuries; hepatocellular carci noma; lung adenocarcinoma; FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 133117346 | 133808647 | Rat | 340 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1318576 | FOXP1 | forkhead box P1 | This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-bind ing- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] | 3 | 70954708 | 71583978 | Human | 491 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1318577 | Foxp1 | forkhead box P1 | Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; identical protein binding activity; and transcription coregulator binding activity. Involved in T follicular helper cell differentiation; nervous system development; and regulation of gene expression. Acts upstream of or within with a positive effect on regulation of androgen receptor signaling pathway. Acts upstream of or within several processes, including positive regulation of cell population proliferation; regulation of gene expression; and striated muscle tissue development. Located in nucleus. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and musculoskeletal system. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; congenital heart disease; esophagus adenocarcinoma; intellectual disability-severe speech delay-mild dysmorphism syndrome; and peritonitis. Orthologous to human FOXP1 (forkhead box P1). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 98902303 | 99510587 | Mouse | 386 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8829581 | Foxp1 | forkhead box P1 | ENCODES a protein that exhibits chromatin binding (ortholog); core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN cardiac muscle cell differentiation (ortholog); cellular response to ionomycin (ortholog); cellular response to tumor necrosis factor (ortholog); ASSOCIATED WITH atrial heart septal defect 1 (ortholog); atrioventricular septal defect (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | NW_004955421 | 16595445 | 17075923 | Chinchilla | 127 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11898748 | FOXP1 | forkhead box P1 | ENCODES a protein that exhibits chromatin binding (ortholog); transcription cis-regulatory region binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN cardiac muscle cell differentiation (ortholog); cellular response to ionomycin (ortholog); cellular response to tumor necros is factor (ortholog); ASSOCIATED WITH atrial heart septal defect 1 (ortholog); atrioventricular septal defect (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | 3 | 70893933 | 71523892 | Bonobo | 134 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12276178 | FOXP1 | forkhead box P1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN cardiac muscle cell differentiation (ortholog); cellular response to ionomycin (ortholog ); cellular response to tumor necrosis factor (ortholog); ASSOCIATED WITH atrial heart septal defect 1 (ortholog); atrioventricular septal defect (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | 20 | 20438631 | 21020516 | Dog | 135 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12503061 | Foxp1 | forkhead box P1 | ENCODES a protein that exhibits chromatin binding (ortholog); transcription cis-regulatory region binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN cardiac muscle cell differentiation (ortholog); cellular response to ionomycin (ortholog); cellular response to tumor necros is factor (ortholog); ASSOCIATED WITH atrial heart septal defect 1 (ortholog); atrioventricular septal defect (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | NW_004936603 | 2631781 | 3146104 | Squirrel | 134 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14036541 | FOXP1 | forkhead box P1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN cardiac muscle cell differentiation (ortholog); cellular response to ionomycin (ortholog ); cellular response to tumor necrosis factor (ortholog); ASSOCIATED WITH atrial heart septal defect 1 (ortholog); atrioventricular septal defect (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 135 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18592191 | FOXP1 | forkhead box P1 | ENCODES a protein that exhibits chromatin binding (ortholog); transcription cis-regulatory region binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN cardiac muscle cell differentiation (ortholog); cellular response to ionomycin (ortholog); cellular response to tumor necros is factor (ortholog); ASSOCIATED WITH atrial heart septal defect 1 (ortholog); atrioventricular septal defect (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 134 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625949055 | Foxp1 | forkhead box P1 | ENCODES a protein that exhibits chromatin binding (ortholog); core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN cardiac muscle cell differentiation (ortholog); cellular response to ionomycin (ortholog); cellular response to tumor necrosis factor (ortholog); ASSOCIATED WITH atrial heart septal defect 1 (ortholog); atrioventricular septal defect (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 127 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255418 | foxp1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18899854 | Foxp1 | forkhead box P1 | ENCODES a protein that exhibits chromatin binding (ortholog); transcription cis-regulatory region binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN cardiac muscle cell differentiation (ortholog); cellular response to ionomycin (ortholog); cellular response to tumor necros is factor (ortholog); ASSOCIATED WITH atrial heart septal defect 1 (ortholog); atrioventricular septal defect (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 134 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255419 | foxp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155256150 | foxp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 153344614 | FOXP1-DT | FOXP1 divergent transcript | INTERACTS WITH okadaic acid | 3 | 71584943 | 71587409 | Human | 1 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16565574 | FOXP1-DT | FOXP1 divergent transcript | | | | | Human | | symbol , COSMIC , name , Human Proteome Map | gene, lncrna |
| 9590047 | FOXP1-AS1 | FOXP1 antisense RNA 1 | | 3 | 71289758 | 71305854 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 11667315 | FOXP1-IT1 | FOXP1 intronic transcript 1 | INTERACTS WITH 2-hydroxypropanoic acid; rac-lactic acid; valproic acid | | | | Human | 3 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna |
| 16567194 | AC097634.2 | novel transcript, antisense to FOXP1 | | | | | Human | | name | gene, lncrna |
| 16568362 | AC097634.3 | novel transcript, antisense to FOXP1 | | | | | Human | | name | gene, lncrna |