Fip1l1 Gene Search Result

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16 records found for search term Fip1l1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1309336	Fip1l1	factor interacting with PAPOLA and CPSF1	ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN mRNA 3'-end processing (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; mRNA decay pathway; ASSOCIATED WITH congestive heart failure (ortholog); Eosinophilia (ortho ... (more) log); hypereosinophilic syndrome (ortholog); FOUND IN mRNA cleavage and polyadenylation specificity factor complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene	14	33969341	34030871	Rat	98	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1319628	FIP1L1	factor interacting with PAPOLA and CPSF1	This gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-rich sequences of pre-mRNA and stimulates poly(A) polymerase activity. I ... (more) ts N-terminus contains a PAP-binding site and its C-terminus an RNA-binding domain. An interstitial chromosomal deletion on 4q12 creates an in-frame fusion of human genes FIP1L1 and PDGFRA (platelet-derived growth factor receptor, alpha). The FIP1L1-PDGFRA fusion gene encodes a constitutively activated tyrosine kinase that joins the first 233 amino acids of FIP1L1 to the last 523 amino acids of PDGFRA. This gene fusion and chromosomal deletion is the cause of some forms of idiopathic hypereosinophilic syndrome (HES). This syndrome, recently reclassified as chronic eosinophilic leukemia (CEL), is responsive to treatment with tyrosine kinase inhibitors. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]	4	53377641	53460862	Human	137	symbol , old_gene_name , COSMIC , description , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1319629	Fip1l1	factor interacting with PAPOLA and CPSF1	Predicted to enable enzyme regulator activity. Predicted to be involved in mRNA processing. Predicted to act upstream of or within regulation of mRNA 3'-end processing. Located in nucleus. Part of mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human FIP1L1 ... (more) ight:700;'>FIP1L1 (factor interacting with PAPOLA and CPSF1). [provided by Alliance of Genome Resources, Jul 2025]	5	74695774	74759451	Mouse	97	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8884717	Fip1l1	factor interacting with PAPOLA and CPSF1	INVOLVED IN mRNA 3'-end processing (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH congestive heart failure (ortholog); Eosinophilia (ortholog); hypereosinophilic syndrome (ortholog); FOUND IN mRNA cleavage and poly ... (more) adenylation specificity factor complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog)	NW_004955447	17265269	17334197	Chinchilla	18	symbol	gene, protein-coding, MODEL [RefSeq]
11780097	FIP1L1	factor interacting with PAPOLA and CPSF1	INVOLVED IN mRNA 3'-end processing (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH congestive heart failure (ortholog); Eosinophilia (ortholog); hypereosinophilic syndrome (ortholog); FOUND IN nucleoplasm (ortholog)	4	70495627	70579059	Bonobo	19	symbol	gene, protein-coding, MODEL [RefSeq]
12086273	FIP1L1	factor interacting with PAPOLA and CPSF1	INVOLVED IN mRNA 3'-end processing (inferred); mRNA processing (inferred); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH congestive heart failure (ortholog); Eosinophilia (ortholog); hypereosinophilic syndrome (ortholog); FOU ... (more) ND IN nucleoplasm (inferred); nucleus (inferred)	13	46011473	46083024	Dog	20	symbol	gene, protein-coding, MODEL [RefSeq]
12677127	Fip1l1	factor interacting with PAPOLA and CPSF1	INVOLVED IN mRNA 3'-end processing (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH congestive heart failure (ortholog); Eosinophilia (ortholog); hypereosinophilic syndrome (ortholog); FOUND IN nucleoplasm (ortholog)	NW_004936482	16126608	16194729	Squirrel	19	symbol	gene, protein-coding, MODEL [RefSeq]
13912989	FIP1L1	factor interacting with PAPOLA and CPSF1	INVOLVED IN mRNA 3'-end processing (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH congestive heart failure (ortholog); Eosinophilia (ortholog); hypereosinophilic syndrome (ortholog); FOUND IN nucleoplasm (ortholog) ... (more) ; INTERACTS WITH deoxynivalenol				Pig	23	symbol	gene, protein-coding, MODEL [RefSeq]
18906070	Fip1l1	factor interacting with PAPOLA and CPSF1	INVOLVED IN mRNA 3'-end processing (inferred); mRNA processing (inferred); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH congestive heart failure (ortholog); Eosinophilia (ortholog); hypereosinophilic syndrome (ortholog); FOU ... (more) ND IN mRNA cleavage and polyadenylation specificity factor complex (inferred); nucleoplasm (inferred); nucleus (inferred)				Naked Mole-Rat	19	symbol	gene, protein-coding, MODEL [RefSeq]
18635746	FIP1L1	factor interacting with PAPOLA and CPSF1	INVOLVED IN mRNA 3'-end processing (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH congestive heart failure (ortholog); Eosinophilia (ortholog); hypereosinophilic syndrome (ortholog); FOUND IN nucleoplasm (ortholog)				Green Monkey	19	symbol	gene, protein-coding, MODEL [RefSeq]
155233981	fip1l1						Tropical Clawed Frog		symbol	gene, null
625934332	Fip1l1	factor interacting with PAPOLA and CPSF1	INVOLVED IN mRNA 3'-end processing (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH congestive heart failure (ortholog); Eosinophilia (ortholog); hypereosinophilic syndrome (ortholog); FOUND IN mRNA cleavage and poly ... (more) adenylation specificity factor complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog)				Black Rat	18	symbol	gene, protein-coding, MODEL [RefSeq]
155233982	fip1l1.L						African Clawed Frog		symbol	gene, null
155247908	fip1l1.S						African Clawed Frog		symbol	gene, null
38603237	FIP1L1-AS1	FIP1L1 antisense RNA 1		4	53374169	53377876	Human		symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
16570009	AC058822.1	novel FIP1L1-PDGFRA fusion protein	ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN cell surface receptor protein tyrosine kinase signaling pathway (inferred); mRNA processing (inferred); FOUND IN nucleoplasm				Human	17	name	gene, protein-coding