| 1305095 | Fbxo24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN nucleus (ortholog); SCF ubiquitin ligase complex (ortholog); INTERACTS WITH bisphenol A; c admium dichloride; endosulfan | 12 | 24709449 | 24719851 | Rat | 56 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312922 | FBXO24 | F-box protein 24 | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependen t ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] | 7 | 100586328 | 100601117 | Human | 61 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312923 | Fbxo24 | F-box protein 24 | Acts upstream of or within several processes, including RNA processing; axoneme assembly; and spermatogenesis. Part of SCF ubiquitin ligase complex. Is expressed in heart and limb mesenchyme. Orthologous to human FBXO24 (F-box protein 24). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 137610767 | 137623340 | Mouse | 77 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8945300 | Fbxo24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN nucleus (ortholog); SCF ubiquitin ligase complex (ortholog) | NW_004955573 | 305516 | 313107 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11936494 | FBXO24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog) | 7 | 92613416 | 92628289 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12360045 | FBXO24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog) | 6 | 9091083 | 9102062 | Dog | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12689750 | Fbxo24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog) | NW_004936543 | 645866 | 653764 | Squirrel | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18449452 | FBXO24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog) | | | | Green Monkey | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155235836 | fbxo24 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626151074 | Fbxo24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN nucleus (ortholog); SCF ubiquitin ligase complex (ortholog) | | | | Black Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14157969 | FBXO24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog) | | | | Pig | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18908540 | Fbxo24 | F-box protein 24 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN axoneme assembly (ortholog); chromatin organization (ortholog); cilium organization (ortholog); FOUND IN nucleus (ortholog); SCF ubiquitin ligase complex (ortholog) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155249420 | fbxo24.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1315402 | Chuk | conserved helix-loop-helix ubiquitous kinase | Enables IkappaB kinase activity. Involved in several processes, including integrin-mediated signaling pathway; positive regulation of interferon-alpha production; and response to virus. Acts upstream of or within several processes, including mammary gland development; negative regulation of canonica l NF-kappaB signal transduction; and osteoclast differentiation. Located in cytoplasmic side of plasma membrane. Part of CD40 receptor complex and IkappaB kinase complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and limb. Used to study fetal encasement syndrome. Human ortholog(s) of this gene implicated in fetal encasement syndrome; liver cancer; and prostate cancer. Orthologous to human CHUK (component of inhibitor of nuclear factor kappa B kinase complex). [provided by Alliance of Genome Resources, Apr 2025] | 19 | 44061773 | 44095940 | Mouse | 732 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
