| 1305346 | Farp1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity; small GTPase binding; INVOLVED IN dendrite morphogenesis; postsynaptic actin cytoskeleton organization; regulation of presynapse assembly; ASSOCIATED WITH basal cell carcinoma (ortholog); substance-related disorder (ortholog ); FOUND IN cytoplasmic side of plasma membrane; cytosol; dendrite; INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 15 | 104531196 | 104770148 | Rat | 189 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1313320 | FARP1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions i n neurons to promote dendritic growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] | 13 | 98142589 | 98455176 | Human | 188 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1313321 | Farp1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | Enables guanyl-nucleotide exchange factor activity. Involved in Rac protein signal transduction; enzyme-linked receptor protein signaling pathway; and positive regulation of skeletal muscle acetylcholine-gated channel clustering. Predicted to be located in cytoplasmic side of plasma membrane; cytoso l; and dendrite. Predicted to be active in glutamatergic synapse. Predicted to be extrinsic component of postsynaptic membrane. Is expressed in lung epithelium; nephron; nervous system; and retina. Orthologous to human FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 121272563 | 121521156 | Mouse | 201 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8925671 | Farp1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); enzyme-linked receptor protein signaling pathway (ortholog); postsynaptic actin cytoskeleton organization (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); substance-related disorder (ortholog); FOUND IN cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog); dendrite (ortholog) | NW_004955404 | 12050225 | 12316842 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11681312 | FARP1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); postsynaptic actin cytoskeleton organization (ortholog); regulation of presynapse assembly (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); substance-related disorder (ortholog ); FOUND IN cytoplasmic side of plasma membrane (ortholog); extrinsic component of postsynaptic membrane (ortholog); glutamatergic synapse (ortholog) | 13 | 79300995 | 79615649 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12172899 | FARP1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); postsynaptic actin cytoskeleton organization (ortholog); regulation of presynapse assembly (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); substance-related disorder (ortholog ); FOUND IN cytoplasmic side of plasma membrane (ortholog); extrinsic component of postsynaptic membrane (ortholog); glutamatergic synapse (ortholog) | 22 | 48284961 | 48575007 | Dog | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12581076 | Farp1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); postsynaptic actin cytoskeleton organization (ortholog); regulation of presynapse assembly (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); substance-related disorder (ortholog ); FOUND IN cytoplasmic side of plasma membrane (ortholog); extrinsic component of postsynaptic membrane (ortholog); glutamatergic synapse (ortholog) | NW_004936472 | 11891234 | 12100202 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13927957 | FARP1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); postsynaptic actin cytoskeleton organization (ortholog); regulation of presynapse assembly (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); substance-related disorder (ortholog ); FOUND IN cytoplasmic side of plasma membrane (ortholog); extrinsic component of postsynaptic membrane (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18673685 | FARP1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); postsynaptic actin cytoskeleton organization (ortholog); regulation of presynapse assembly (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); substance-related disorder (ortholog ); FOUND IN cytoplasmic side of plasma membrane (ortholog); extrinsic component of postsynaptic membrane (ortholog); glutamatergic synapse (ortholog) | | | | Green Monkey | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285143786 | farp1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625973700 | Farp1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); enzyme-linked receptor protein signaling pathway (ortholog); postsynaptic actin cytoskeleton organization (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); substance-related disorder (ortholog); FOUND IN cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog); dendrite (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921984 | Farp1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); enzyme-linked receptor protein signaling pathway (ortholog); postsynaptic actin cytoskeleton organization (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); substance-related dis order (ortholog); FOUND IN cytoplasmic side of plasma membrane (ortholog); extrinsic component of postsynaptic membrane (ortholog); glutamatergic synapse (ortholog) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 405864302 | farp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864149 | farp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857658 | farp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859532 | farp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626172479 | farp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626183273 | farp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863621 | farp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863041 | farp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859232 | farp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626178405 | farp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405865533 | farp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 6481287 | FARP1-AS1 | FARP1 antisense RNA 1 | | 13 | 98435405 | 98435840 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16565222 | AL161896.1 | novel transcript, antisense to FARP1 | | | | | Human | | name | gene, lncrna |
| 16565134 | AL445223.1 | novel transcript, sense intronic to FARP1 | | | | | Human | | name | gene, lncrna |