| 2583 | Ets1 | ETS proto-oncogene 1, transcription factor | ENCODES a protein that exhibits histone acetyltransferase binding; sequence-specific DNA binding; DNA binding (ortholog); INVOLVED IN angiogenesis involved in wound healing; cellular response to hydrogen peroxide; estrous cycle; PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH decreased circulating creatinine level; increased tubuloglomerular feedback response; ASSOCIATED WITH Experimental Diabetes Mellitus; Mouth Neoplasms; celiac disease (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); transcription regulator complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate | 8 | 39303936 | 39426022 | Rat | 337 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 10554 | Ets1 | Ets proto-oncogene 1, transcription factor | Enables DNA-binding transcription factor activity; DNA-binding transcription factor binding activity; and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of inflammatory response and positive regulation of transcription by RNA polymerase II. Acts upstream of o r within regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 32547501 | 32669116 | Mouse | 382 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 737031 | ETS1 | ETS proto-oncogene 1, transcription factor | This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerou s genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] | 11 | 128458765 | 128587558 | Human | 355 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8852638 | Ets1 | ETS proto-oncogene 1, transcription factor | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN angiogenesis involved in wound healing (ortholog); cell motility (ortholog); cellular respons e to hydrogen peroxide (ortholog); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH celiac disease (ortholog); Experimental Diabetes Mellitus (ortholog); Mouth Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); transcription regulator complex (ortholog) | NW_004955412 | 29433730 | 29602389 | Chinchilla | 92 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11712887 | ETS1 | ETS proto-oncogene 1, transcription factor | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); histone acetyltransferase binding (ortholog); nucleic acid binding (ortholog); INVOLVED IN angiogenesis involved in wound healing (ortholog); cellular response to hydrogen peroxide (ortholog); estrous cycle (ortholo g); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH celiac disease (ortholog); Experimental Diabetes Mellitus (ortholog); Mouth Neoplasms (ortholog); FOUND IN transcription regulator complex (ortholog) | 11 | 123272111 | 123400413 | Bonobo | 97 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12167277 | ETS1 | ETS proto-oncogene 1, transcription factor | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor binding (ortholog); histone acetyltransferase binding (ortholog); INVOLVED IN angiogenesis involved in wound healing (ortholog); cell motility (orthol og); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH celiac disease (ortholog); Experimental Diabetes Mellitus (ortholog); Mouth Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); transcription regulator complex (ortholog) | 5 | 6059023 | 6189516 | Dog | 97 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12726529 | Ets1 | ETS proto-oncogene 1, transcription factor | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); histone acetyltransferase binding (ortholog); nucleic acid binding (ortholog); INVOLVED IN angiogenesis involved in wound healing (ortholog); cellular response to hydrogen peroxide (ortholog); estrous cycle (ortholo g); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH celiac disease (ortholog); Experimental Diabetes Mellitus (ortholog); Mouth Neoplasms (ortholog); FOUND IN transcription regulator complex (ortholog) | NW_004936572 | 3728971 | 3795612 | Squirrel | 96 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14087045 | ETS1 | ETS proto-oncogene 1, transcription factor | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); histone acetyltransferase binding (ortholog); nucleic acid binding (ortholog); INVOLVED IN angiogenesis involved in wound healing (ortholog); cellular response to hydrogen peroxide (ortholog); estrous cycle (ortholo g); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH celiac disease (ortholog); Experimental Diabetes Mellitus (ortholog); Mouth Neoplasms (ortholog); FOUND IN transcription regulator complex (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 97 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155245390 | ets1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18732488 | ETS1 | ETS proto-oncogene 1, transcription factor | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); histone acetyltransferase binding (ortholog); nucleic acid binding (ortholog); INVOLVED IN angiogenesis involved in wound healing (ortholog); cellular response to hydrogen peroxide (ortholog); estrous cycle (ortholo g); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH celiac disease (ortholog); Experimental Diabetes Mellitus (ortholog); Mouth Neoplasms (ortholog); FOUND IN transcription regulator complex (ortholog) | | | | Green Monkey | 97 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625908805 | Ets1 | ETS proto-oncogene 1, transcription factor | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN angiogenesis involved in wound healing (ortholog); cell motility (ortholog); cellular respons e to hydrogen peroxide (ortholog); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH celiac disease (ortholog); Experimental Diabetes Mellitus (ortholog); Mouth Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); transcription regulator complex (ortholog) | | | | Black Rat | 92 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922769 | Ets1 | ETS proto-oncogene 1, transcription factor | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor binding (ortholog); histone acetyltransferase binding (ortholog); INVOLVED IN angiogenesis involved in wound healing (ortholog); cell motility (orthol og); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH celiac disease (ortholog); Experimental Diabetes Mellitus (ortholog); Mouth Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); transcription regulator complex (ortholog) | | | | Naked Mole-Rat | 96 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155245389 | ets1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155252279 | ets1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 13702133 | ETS1-AS1 | ETS1 antisense RNA 1 | | 11 | 128526142 | 128530383 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 4139856 | Ets1em1Mcwi | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); zinc finger nuclease induced mutant 1, Medical College of Wisconsin | ASSOCIATED WITH decreased circulating creatinine level; increased tubuloglomerular feedback response | | | | Rat | 2 | symbol , old_gene_symbol | gene, allele |
| 1345950 | DAXX | death domain associated protein | This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleu s, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008] | 6 | 33318558 | 33322959 | Human | 321 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1348894 | TDP2 | tyrosyl-DNA phosphodiesterase 2 | This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and st ructural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008] | 6 | 24649979 | 24666899 | Human | 108 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 732545 | MAFB | MAF bZIP transcription factor B | The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns. [provided by RefSeq, Jul 2008] | 20 | 40685848 | 40689236 | Human | 470 | description | gene, protein-coding, REVIEWED [RefSeq] |
