| 1352223 | ELP4 | elongator acetyltransferase complex subunit 4 | This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 > deletion mutants. This gene has also been associated with Rolandic epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] | 11 | 31509767 | 31790324 | Human | 103 | symbol , COSMIC , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1558136 | Elp4 | elongator acetyltransferase complex subunit 4 | Predicted to enable phosphorylase kinase regulator activity. Predicted to contribute to RNA polymerase II complex binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and tRNA wobble uridine modification. Predicted to be located in nucleoplasm. Predicted to be part of elongator holoenzyme complex and transcription elongation factor complex. Predicted to be active in cytoplasm. Is expressed in several structures, including eye and telencephalon. Human ortholog(s) of this gene implicated in aniridia. Orthologous to human ELP4 (elongator acetyltransferase complex subunit 4). [provided by Alliance of Genome Resources, Apr 2025] | 2 | 105527665 | 105734909 | Mouse | 104 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566052 | Elp4 | elongator acetyltransferase complex subunit 4 | INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN cytoplasm (ortholog); elongator holoenzyme complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH bisphenol A; oxaliplatin; topotec an | 3 | 112617020 | 112839963 | Rat | 87 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8764029 | Elp4 | elongator acetyltransferase complex subunit 4 | INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN cytoplasm (ortholog); elongator holoenzyme complex (ortholog); nucleoplasm (ortholog) | NW_004955476 | 9850110 | 10054313 | Chinchilla | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11801287 | ELP4 | elongator acetyltransferase complex subunit 4 | INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN cytoplasm (ortholog); elongator holoenzyme complex (ortholog); nucleoplasm (ortholog) | 11 | 31473439 | 31754446 | Bonobo | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12132556 | ELP4 | elongator acetyltransferase complex subunit 4 | INVOLVED IN regulation of transcription by RNA polymerase II (inferred); tRNA processing (inferred); tRNA wobble uridine modification (inferred); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN cytoplasm (inferred); elongator holoenzyme complex (inferred); nucleoplasm (inferred) | 18 | 35638606 | 35880194 | Dog | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12688459 | Elp4 | elongator acetyltransferase complex subunit 4 | INVOLVED IN regulation of transcription by RNA polymerase II (inferred); tRNA processing (inferred); tRNA wobble uridine modification (inferred); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN cytoplasm (inferred); elongator holoenzyme complex (inferred); nucleoplasm (inferred) | NW_004936533 | 5985873 | 6216124 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14213490 | ELP4 | elongator acetyltransferase complex subunit 4 | INVOLVED IN regulation of transcription by RNA polymerase II (inferred); tRNA processing (inferred); tRNA wobble uridine modification (inferred); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN cytoplasm (inferred); elongator holoenzyme complex (inferred); nucleoplasm (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18899577 | Elp4 | elongator acetyltransferase complex subunit 4 | INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18343659 | ELP4 | elongator acetyltransferase complex subunit 4 | INVOLVED IN regulation of transcription by RNA polymerase II (inferred); tRNA processing (inferred); tRNA wobble uridine modification (inferred); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN cytoplasm (inferred); elongator holoenzyme complex (inferred); nucleoplasm (inferred) | | | | Green Monkey | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626134804 | Elp4 | elongator acetyltransferase complex subunit 4 | INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN cytoplasm (ortholog); elongator holoenzyme complex (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14376321 | ELP4 | | | | | | Yeast | | symbol | gene, null |
| 155235621 | elp4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 405858530 | elp4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861858 | elp4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468958 | elp4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862429 | elp4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856619 | elp4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155235622 | elp4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 597621580 | ELP4-AS1 | ELP4 antisense RNA 1 | | 11 | 31689023 | 31767891 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1592018 | Elp4-ps1 | elongator acetyltransferase complex subunit 4, pseudogene 1 | INVOLVED IN tRNA processing (inferred); tRNA wobble uridine modification (inferred); FOUND IN cytoplasm (inferred); elongator holoenzyme complex (inferred); nucleus (inferred) | 2 | 175027230 | 175028848 | Rat | 8 | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 16553976 | AC131571.1 | novel transcript, antisense to ELP4 | | | | | Human | | name | gene, lncrna |