ELP4 (elongator acetyltransferase complex subunit 4) - Rat Genome Database

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Gene: ELP4 (elongator acetyltransferase complex subunit 4) Canis lupus familiaris
Analyze
Symbol: ELP4
Name: elongator acetyltransferase complex subunit 4
RGD ID: 12132556
Description: ENCODES a protein that exhibits RNA polymerase II complex binding (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); tRNA processing (inferred); tRNA wobble uridine modification (inferred); ASSOCIATED WITH aniridia (ortholog); aniridia 1 (ortholog); Aniridia 2 (ortholog); FOUND IN cytoplasm (inferred); elongator holoenzyme complex (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: elongation protein 4 homolog; elongator complex protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11835,638,606 - 35,880,194 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1835,639,011 - 36,024,005 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1835,287,764 - 35,529,314 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01836,282,362 - 36,524,334 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1836,282,375 - 36,667,220 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11835,855,939 - 36,097,717 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01835,437,230 - 35,678,935 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01836,072,284 - 36,314,202 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ELP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11835,638,606 - 35,880,194 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1835,639,011 - 36,024,005 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1835,287,764 - 35,529,314 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01836,282,362 - 36,524,334 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1836,282,375 - 36,667,220 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11835,855,939 - 36,097,717 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01835,437,230 - 35,678,935 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01836,072,284 - 36,314,202 (-)NCBIUU_Cfam_GSD_1.0
ELP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381131,509,767 - 31,790,324 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1131,509,755 - 31,790,324 (+)EnsemblGRCh38hg38GRCh38
GRCh371131,531,314 - 31,811,872 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361131,487,873 - 31,761,905 (+)NCBINCBI36Build 36hg18NCBI36
Build 341131,487,900 - 31,761,895NCBI
Celera1131,678,743 - 31,952,788 (+)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1131,226,047 - 31,500,747 (+)NCBIHuRef
CHM1_11131,530,849 - 31,804,836 (+)NCBICHM1_1
T2T-CHM13v2.01131,645,605 - 31,926,139 (+)NCBIT2T-CHM13v2.0
Elp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392105,527,665 - 105,734,909 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2105,531,372 - 105,734,909 (-)EnsemblGRCm39 Ensembl
GRCm382105,697,320 - 105,904,564 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2105,701,027 - 105,904,564 (-)EnsemblGRCm38mm10GRCm38
MGSCv372105,540,266 - 105,744,657 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362105,500,948 - 105,705,339 (-)NCBIMGSCv36mm8
Celera2106,921,492 - 107,127,004 (-)NCBICelera
Cytogenetic Map2E3NCBI
cM Map255.33NCBI
Elp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83112,617,020 - 112,839,963 (-)NCBIGRCr8
mRatBN7.2392,162,271 - 92,385,251 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl392,162,280 - 92,385,243 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx395,658,082 - 95,881,042 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03104,257,011 - 104,479,972 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03102,085,027 - 102,307,989 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0395,733,810 - 95,954,987 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03102,353,650 - 102,575,110 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4391,154,930 - 91,309,491 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera391,216,738 - 91,434,730 (-)NCBICelera
Cytogenetic Map3q33NCBI
Elp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554769,849,365 - 10,054,583 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554769,850,110 - 10,054,313 (+)NCBIChiLan1.0ChiLan1.0
ELP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2933,720,033 - 33,994,711 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11133,724,543 - 33,999,182 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01131,473,439 - 31,754,446 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11131,362,973 - 31,637,425 (+)NCBIpanpan1.1PanPan1.1panPan2
Elp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494732,859,776 - 33,091,342 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365335,986,322 - 6,216,145 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365335,985,873 - 6,216,124 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl229,004,987 - 29,230,077 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1229,006,456 - 29,230,092 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2231,513,261 - 31,737,288 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ELP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1133,419,313 - 33,679,046 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl133,421,038 - 33,678,990 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038130,576,771 - 130,842,413 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476620,343,803 - 20,531,873 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476620,343,776 - 20,536,627 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ELP4
1946 total Variants

Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014121289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022405381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038424192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038424193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038424194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038500541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038500542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038500544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038563120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038563121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038563122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038627240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038627241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038627242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_540560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_014121289   ⟹   XP_013976764
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11835,638,606 - 35,880,194 (-)NCBI
Dog10K_Boxer_Tasha1835,287,764 - 35,529,314 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022405381   ⟹   XP_022261089
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11835,712,659 - 35,880,194 (-)NCBI
Dog10K_Boxer_Tasha1835,361,712 - 35,529,314 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038424192   ⟹   XP_038280120
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01836,282,362 - 36,524,334 (-)NCBI
RefSeq Acc Id: XM_038424193   ⟹   XP_038280121
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01836,282,362 - 36,524,334 (-)NCBI
RefSeq Acc Id: XM_038424194   ⟹   XP_038280122
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01836,356,344 - 36,524,334 (-)NCBI
RefSeq Acc Id: XM_038500541   ⟹   XP_038356469
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11835,855,939 - 36,097,717 (-)NCBI
RefSeq Acc Id: XM_038500542   ⟹   XP_038356470
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11835,855,939 - 36,097,717 (-)NCBI
RefSeq Acc Id: XM_038500544   ⟹   XP_038356472
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11835,929,918 - 36,097,717 (-)NCBI
RefSeq Acc Id: XM_038563120   ⟹   XP_038419048
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01836,072,284 - 36,314,202 (-)NCBI
RefSeq Acc Id: XM_038563121   ⟹   XP_038419049
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01836,072,284 - 36,314,202 (-)NCBI
RefSeq Acc Id: XM_038563122   ⟹   XP_038419050
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01836,146,244 - 36,314,202 (-)NCBI
RefSeq Acc Id: XM_038627240   ⟹   XP_038483168
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01835,437,230 - 35,678,935 (-)NCBI
RefSeq Acc Id: XM_038627241   ⟹   XP_038483169
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01835,437,230 - 35,678,935 (-)NCBI
RefSeq Acc Id: XM_038627242   ⟹   XP_038483170
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01835,511,241 - 35,678,935 (-)NCBI
RefSeq Acc Id: XM_540560   ⟹   XP_540560
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11835,638,606 - 35,880,193 (-)NCBI
Dog10K_Boxer_Tasha1835,287,764 - 35,529,314 (-)NCBI
Sequence:
RefSeq Acc Id: XP_540560   ⟸   XM_540560
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JLK6 (UniProtKB/TrEMBL),   A0A8I3QG50 (UniProtKB/TrEMBL),   A0A8P0SXG6 (UniProtKB/TrEMBL),   A0A8C0TEI3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013976764   ⟸   XM_014121289
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TEI3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022261089   ⟸   XM_022405381
- Peptide Label: isoform X3
- UniProtKB: A0A8C0TEI3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038356470   ⟸   XM_038500542
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038356469   ⟸   XM_038500541
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038356472   ⟸   XM_038500544
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038483169   ⟸   XM_038627241
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038483168   ⟸   XM_038627240
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038483170   ⟸   XM_038627242
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038280121   ⟸   XM_038424193
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JLK6 (UniProtKB/TrEMBL),   A0A8I3QG50 (UniProtKB/TrEMBL),   A0A8P0SXG6 (UniProtKB/TrEMBL),   A0A8C0TEI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038280120   ⟸   XM_038424192
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TEI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038280122   ⟸   XM_038424194
- Peptide Label: isoform X3
- UniProtKB: A0A8C0TEI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038419049   ⟸   XM_038563121
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JLK6 (UniProtKB/TrEMBL),   A0A8C0TEI3 (UniProtKB/TrEMBL),   A0A8I3QG50 (UniProtKB/TrEMBL),   A0A8P0SXG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038419048   ⟸   XM_038563120
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TEI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038419050   ⟸   XM_038563122
- Peptide Label: isoform X3
- UniProtKB: A0A8C0TEI3 (UniProtKB/TrEMBL)
Protein Domains
J

Promoters
RGD ID:13686491
Promoter ID:EPDNEW_C4557
Type:multiple initiation site
Name:ELP4_1
Description:elongator acetyltransferase complex subunit 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_C4559  
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11835,880,171 - 35,880,231EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007510 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040020583 UniProtKB/TrEMBL
  ENSCAFG00845028184 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000012029.5 UniProtKB/TrEMBL
  ENSCAFT00000047952.4 UniProtKB/TrEMBL
  ENSCAFT00000062465.2 UniProtKB/TrEMBL
  ENSCAFT00000064425.2 UniProtKB/TrEMBL
  ENSCAFT00000067505.2 UniProtKB/TrEMBL
  ENSCAFT00000080725.2 UniProtKB/TrEMBL
  ENSCAFT00000101982.1 UniProtKB/TrEMBL
  ENSCAFT00040038104.1 UniProtKB/TrEMBL
  ENSCAFT00040038152.1 UniProtKB/TrEMBL
  ENSCAFT00040038395.1 UniProtKB/TrEMBL
  ENSCAFT00040038436.1 UniProtKB/TrEMBL
  ENSCAFT00040038455.1 UniProtKB/TrEMBL
  ENSCAFT00845049729.1 UniProtKB/TrEMBL
  ENSCAFT00845049786.1 UniProtKB/TrEMBL
  ENSCAFT00845049838.1 UniProtKB/TrEMBL
  ENSCAFT00845049942 ENTREZGENE
  ENSCAFT00845049942.1 UniProtKB/TrEMBL
  ENSCAFT00845049960.1 UniProtKB/TrEMBL
  ENSCAFT00845049995.1 UniProtKB/TrEMBL
  ENSCAFT00845050023.1 UniProtKB/TrEMBL
  ENSCAFT00845050107.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.110 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DnaJ_domain UniProtKB/TrEMBL
  Elongator_complex_protein_4 UniProtKB/TrEMBL
  J_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene ELP4 ENTREZGENE
PANTHER ELONGATOR COMPLEX PROTEIN 4 UniProtKB/TrEMBL
  PTHR12896 UniProtKB/TrEMBL
Pfam DnaJ UniProtKB/TrEMBL
  PAXNEB UniProtKB/TrEMBL
PRINTS JDOMAIN UniProtKB/TrEMBL
PROSITE DNAJ_2 UniProtKB/TrEMBL
SMART DnaJ UniProtKB/TrEMBL
Superfamily-SCOP SSF46565 UniProtKB/TrEMBL
UniProt A0A8C0JLK6 ENTREZGENE
  A0A8C0TAD7_CANLF UniProtKB/TrEMBL
  A0A8C0TAI6_CANLF UniProtKB/TrEMBL
  A0A8C0TEI3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Z315_CANLF UniProtKB/TrEMBL
  A0A8C0Z3C2_CANLF UniProtKB/TrEMBL
  A0A8I3PVT6_CANLF UniProtKB/TrEMBL
  A0A8I3PW13_CANLF UniProtKB/TrEMBL
  A0A8I3PWV5_CANLF UniProtKB/TrEMBL
  A0A8I3PY34_CANLF UniProtKB/TrEMBL
  A0A8I3Q4I8_CANLF UniProtKB/TrEMBL
  A0A8I3QFW5_CANLF UniProtKB/TrEMBL
  A0A8I3QG50 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3SBF1_CANLF UniProtKB/TrEMBL
  A0A8P0PAA9_CANLF UniProtKB/TrEMBL
  A0A8P0PM40_CANLF UniProtKB/TrEMBL
  A0A8P0SXG6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:108120 ENTREZGENE