| 1310585 | Elf2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regula tion of DNA-templated transcription (ortholog); regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 2 | 137445787 | 137536512 | Rat | 109 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1321579 | ELF2 | E74 like ETS transcription factor 2 | Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of DNA-templated transcription; positive regulation of DNA-templated transcription; and regulation of transcription by RNA polymer ase II. Located in cytosol and nuclear body. [provided by Alliance of Genome Resources, Jul 2025] | 4 | 139057220 | 139177915 | Human | 110 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1321580 | Elf2 | E74-like factor 2 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Predicted to be involved in cell differentiation and regulation of DNA-templated transcription. Predicted to be located in cytosol and nuclear body. P redicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; reproductive system; sensory organ; and urinary system. Orthologous to human ELF2 (E74 like ETS transcription factor 2). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 51160141 | 51248101 | Mouse | 112 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8802281 | Elf2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regula tion of DNA-templated transcription (ortholog); regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog) | NW_004955428 | 4458962 | 4550783 | Chinchilla | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11775508 | ELF2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Cerebellar Ataxia , Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (inferred); nucleoplasm (inferred); nucleus (inferred) | 4 | 131420985 | 131540691 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12197591 | ELF2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Cerebellar Ataxia , Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (inferred); nucleoplasm (inferred); nucleus (inferred) | 19 | 3482845 | 3580380 | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12625370 | Elf2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Cerebellar Ataxia , Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936535 | 8426550 | 8496129 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14124335 | ELF2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Cerebellar Ataxia , Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18607713 | ELF2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Cerebellar Ataxia , Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625841991 | Elf2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regula tion of DNA-templated transcription (ortholog); regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18927062 | Elf2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240340 | elf2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155240341 | elf2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155259568 | elf2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38632334 | ELF2-DT | ELF2 divergent transcript | | 4 | 139176155 | 139245832 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna, MODEL [RefSeq] |
| 2319506 | Elf2-ps1 | E74 like ETS transcription factor 2, pseudogene 1 | | 16 | 39933244 | 39946242 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1626593 | ELF2P1 | ELF2 pseudogene 1 | | X | 103908424 | 103911366 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1626562 | ELF2P2 | ELF2 pseudogene 2 | | 6 | 1512341 | 1515565 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1626561 | ELF2P3 | ELF2 pseudogene 3 | | 9 | 87816474 | 87819454 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1626543 | ELF2P4 | ELF2 pseudogene 4 | | 2 | 185545722 | 185547818 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16555893 | AC234782.2 | E74-like factor 2 (ELF2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16552321 | AL512329.1 | E74-like factor 2 (ets domain transcription factor) (ELF2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16553185 | AC080125.1 | pseudogene similar to part of E74-like factor 2 (ets domain transcription factor) (ELF2) | | | | | Human | | name | gene, processed_pseudogene |
| 1345835 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also acti vated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021] | 2 | 37099210 | 37156980 | Human | 383 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |