| 1359488 | Ecsit | ECSIT signaling integrator | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); enzyme inhibitor activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell surface receptor protein serine/threonine kinase signaling pathway (ortholog); mesoderm formati on (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial complex I intermediate assembly complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 8 | 28881594 | 28894443 | Rat | 103 | symbol , old_gene_name , PhenoGen , name , ensembl_full_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1557226 | Ecsit | ECSIT signalling integrator | Enables DNA-binding transcription factor activity and chromatin binding activity. Acts upstream of or within BMP signaling pathway; mesoderm formation; and regulation of transcription by RNA polymerase II. Located in mitochondrion. Part of transcription regulator complex. Is expressed in several str uctures, including egg cylinder; embryo mesoderm; and genitourinary system. Orthologous to human ECSIT (ECSIT signaling integrator). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 21982731 | 21997648 | Mouse | 108 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1602709 | ECSIT | ECSIT signaling integrator | Enables molecular adaptor activity. Involved in regulation of oxidoreductase activity; regulation of protein complex stability; and toll-like receptor 4 signaling pathway. Located in cytosol; mitochondrion; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 11505929 | 11529134 | Human | 98 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8825045 | Ecsit | ECSIT signaling integrator | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); enzyme inhibitor activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell surface receptor protein serine/threonine kinase signaling pathway (ortholog); mesoderm formati on (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial complex I intermediate assembly complex (ortholog) | NW_004955495 | 2375992 | 2385962 | Chinchilla | 31 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11735031 | ECSIT | ECSIT signaling integrator | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell surface receptor protein serine/threonine kinase signaling pathway (ortholog); mesoderm formation (ortholog); FOUND IN transcription regulator complex (ortholog) | 19 | 11052057 | 11075308 | Bonobo | 36 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12132645 | ECSIT | ECSIT signaling integrator | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell surface receptor protein serine/threonine kinase signaling pathway (ortholog); mesoderm formation (ortholog); FOUND IN transcription regulator complex (ortholog) | 20 | 49848848 | 49867075 | Dog | 38 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12515230 | Ecsit | ECSIT signaling integrator | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell surface receptor protein serine/threonine kinase signaling pathway (ortholog); mesoderm formation (ortholog); FOUND IN transcription regulator complex (ortholog) | NW_004936659 | 1550192 | 1563534 | Squirrel | 36 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13965281 | ECSIT | ECSIT signaling integrator | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell surface receptor protein serine/threonine kinase signaling pathway (ortholog); mesoderm formation (ortholog); FOUND IN transcription regulator complex (ortholog) | | | | Pig | 38 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626062694 | Ecsit | ECSIT signaling integrator | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); enzyme inhibitor activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell surface receptor protein serine/threonine kinase signaling pathway (ortholog); mesoderm formati on (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial complex I intermediate assembly complex (ortholog) | | | | Black Rat | 31 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14381770 | ECSIT | | | | | | Fly | | symbol | gene, null |
| 18929972 | Ecsit | ECSIT signaling integrator | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); enzyme inhibitor activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell surface receptor protein serine/threonine kinase signaling pathway (ortholog); mesoderm formati on (ortholog); FOUND IN cytosol (ortholog); mitochondrial complex I intermediate assembly complex (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 34 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155243448 | ecsit | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18427897 | ECSIT | ECSIT signaling integrator | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell surface receptor protein serine/threonine kinase signaling pathway (ortholog); mesoderm formation (ortholog); FOUND IN transcription regulator complex (ortholog) | | | | Green Monkey | 36 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155243447 | ecsit.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 6496810 | Ecsit-ps1 | ECSIT signaling integrator, pseudogene 1 | | 1 | 113638270 | 113639434 | Rat | | symbol , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |