| 620357 | Ecm1 | extracellular matrix protein 1 | ENCODES a protein that exhibits interleukin-2 receptor binding (ortholog); protease binding (ortholog); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hep atocellular carcinoma (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 2 | 185976439 | 185981656 | Rat | 191 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1553518 | Ecm1 | extracellular matrix protein 1 | Enables interleukin-2 receptor binding activity. Acts upstream of or within several processes, including regulation of bone mineralization; regulation of type 2 immune response; and skeletal system development. Located in extracellular space. Is expressed in several structures, including alimentary system; autopod; bone; cardiovascular system; and skin. Human ortholog(s) of this gene implicated in lipoid proteinosis. Orthologous to human ECM1 (extracellular matrix protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 95641459 | 95646880 | Mouse | 196 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1605731 | ECM1 | extracellular matrix protein 1 | This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated wi th lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Feb 2011] | 1 | 150508109 | 150513789 | Human | 252 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8876523 | Ecm1 | extracellular matrix protein 1 | ENCODES a protein that exhibits interleukin-2 receptor binding (ortholog); protease binding (ortholog); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hep atocellular carcinoma (ortholog); FOUND IN extracellular space (ortholog) | NW_004955413 | 293295 | 299293 | Chinchilla | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11706495 | ECM1 | extracellular matrix protein 1 | ENCODES a protein that exhibits interleukin-2 receptor binding (inferred); protease binding (inferred); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hep atocellular carcinoma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 1 | 125853337 | 125858904 | Bonobo | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12364310 | ECM1 | extracellular matrix protein 1 | ENCODES a protein that exhibits interleukin-2 receptor binding (inferred); protease binding (inferred); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hep atocellular carcinoma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | 17 | 59696125 | 59701990 | Dog | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12635764 | Ecm1 | extracellular matrix protein 1 | ENCODES a protein that exhibits interleukin-2 receptor binding (inferred); protease binding (inferred); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hep atocellular carcinoma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | NW_004936580 | 750423 | 756765 | Squirrel | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14016472 | ECM1 | extracellular matrix protein 1 | ENCODES a protein that exhibits interleukin-2 receptor binding (inferred); protease binding (inferred); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hep atocellular carcinoma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Pig | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626182467 | ecm1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626099885 | Ecm1 | extracellular matrix protein 1 | ENCODES a protein that exhibits interleukin-2 receptor binding (ortholog); protease binding (ortholog); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hep atocellular carcinoma (ortholog); FOUND IN extracellular space (ortholog) | | | | Black Rat | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626172386 | ecm1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18751207 | ECM1 | extracellular matrix protein 1 | ENCODES a protein that exhibits interleukin-2 receptor binding (inferred); protease binding (inferred); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hep atocellular carcinoma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Green Monkey | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626181134 | ecm1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18914167 | Ecm1 | extracellular matrix protein 1 | ENCODES a protein that exhibits interleukin-2 receptor binding (ortholog); protease binding (ortholog); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hep atocellular carcinoma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred) | | | | Naked Mole-Rat | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 6480815 | FALEC | focally amplified lncRNA regulator of ECM1 | INTERACTS WITH 2-hydroxypropanoic acid; lipopolysaccharide; propofol | 1 | 150515752 | 150536788 | Human | 5 | name | gene, ncrna, VALIDATED [RefSeq] |
| 14376223 | ECM10 | | | | | | Yeast | | symbol | gene, null |
| 14371695 | ECM14 | | | | | | Yeast | | symbol | gene, null |
| 14376230 | ECM16 | | | | | | Yeast | | symbol | gene, null |
| 14368434 | ECM18 | | | | | | Yeast | | symbol | gene, null |
| 8548277 | ECM1P1 | extracellular matrix protein 1 pseudogene 1 | | 9 | 4768630 | 4769895 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 10400028 | ECM1P2 | extracellular matrix protein 1 pseudogene 2 | | 4 | 12639086 | 12641009 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
