| 1305054 | Dntt | DNA nucleotidylexotransferase | ENCODES a protein that exhibits DNA nucleotidylexotransferase activity (ortholog); INVOLVED IN response to ATP; DNA metabolic process (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); FOUND IN chroma tin; euchromatin; nuclear matrix; INTERACTS WITH bisphenol A; (1->4)-beta-D-glucan (ortholog); 17alpha-ethynylestradiol (ortholog) | 1 | 249805802 | 249837685 | Rat | 85 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312854 | DNTT | DNA nucleotidylexotransferase | This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malig nant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008] | 10 | 96304434 | 96338564 | Human | 77 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312855 | Dntt | deoxynucleotidyltransferase, terminal | Enables DNA nucleotidylexotransferase activity. Acts upstream of or within DNA metabolic process. Predicted to be located in cytosol; euchromatin; and nuclear lumen. Predicted to be active in nucleus. Is expressed in bone marrow; ovary; submandibular gland; testis; and thymus. Orthologous to human < span style='font-weight:700;'>DNTT (DNA nucleotidylexotransferase). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 41017701 | 41047964 | Mouse | 99 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9020082 | Dntt | DNA nucleotidylexotransferase | ENCODES a protein that exhibits DNA nucleotidylexotransferase activity (ortholog); INVOLVED IN DNA metabolic process (ortholog); response to ATP (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); FOUN D IN chromatin (ortholog); cytosol (ortholog); euchromatin (ortholog) | NW_004955507 | 2494074 | 2551326 | Chinchilla | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11816960 | DNTT | DNA nucleotidylexotransferase | ENCODES a protein that exhibits DNA binding (inferred); DNA nucleotidylexotransferase activity (inferred); DNA polymerase activity (inferred); INVOLVED IN DNA metabolic process (ortholog); response to ATP (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; A SSOCIATED WITH acute lymphoblastic leukemia (ortholog); FOUND IN chromatin (ortholog); euchromatin (ortholog); nuclear matrix (ortholog) | 10 | 92916783 | 92958216 | Bonobo | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12298528 | DNTT | DNA nucleotidylexotransferase | ENCODES a protein that exhibits DNA binding (inferred); DNA nucleotidylexotransferase activity (inferred); DNA polymerase activity (inferred); INVOLVED IN DNA metabolic process (ortholog); response to ATP (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; A SSOCIATED WITH acute lymphoblastic leukemia (ortholog); FOUND IN chromatin (ortholog); euchromatin (ortholog); nuclear matrix (ortholog) | 28 | 9729812 | 9759019 | Dog | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12643893 | Dntt | DNA nucleotidylexotransferase | ENCODES a protein that exhibits DNA binding (inferred); DNA nucleotidylexotransferase activity (inferred); DNA polymerase activity (inferred); INVOLVED IN DNA metabolic process (ortholog); response to ATP (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; A SSOCIATED WITH acute lymphoblastic leukemia (ortholog); FOUND IN chromatin (ortholog); euchromatin (ortholog); nuclear matrix (ortholog) | NW_004936636 | 3153454 | 3189774 | Squirrel | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14019175 | DNTT | DNA nucleotidylexotransferase | ENCODES a protein that exhibits DNA binding (inferred); DNA nucleotidylexotransferase activity (inferred); DNA polymerase activity (inferred); INVOLVED IN DNA metabolic process (ortholog); response to ATP (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; A SSOCIATED WITH acute lymphoblastic leukemia (ortholog); FOUND IN chromatin (ortholog); euchromatin (ortholog); nuclear matrix (ortholog) | | | | Pig | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18719747 | DNTT | DNA nucleotidylexotransferase | ENCODES a protein that exhibits DNA binding (inferred); DNA nucleotidylexotransferase activity (inferred); DNA polymerase activity (inferred); INVOLVED IN DNA metabolic process (ortholog); response to ATP (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; A SSOCIATED WITH acute lymphoblastic leukemia (ortholog); FOUND IN chromatin (ortholog); euchromatin (ortholog); nuclear matrix (ortholog) | | | | Green Monkey | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18923909 | Dntt | DNA nucleotidylexotransferase | ENCODES a protein that exhibits DNA binding (inferred); DNA nucleotidylexotransferase activity (inferred); DNA polymerase activity (inferred); INVOLVED IN DNA metabolic process (ortholog); response to ATP (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; A SSOCIATED WITH acute lymphoblastic leukemia (ortholog); FOUND IN chromatin (ortholog); cytosol (ortholog); euchromatin (ortholog) | | | | Naked Mole-Rat | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288057135 | dntt | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626118985 | Dntt | DNA nucleotidylexotransferase | ENCODES a protein that exhibits DNA nucleotidylexotransferase activity (ortholog); INVOLVED IN DNA metabolic process (ortholog); response to ATP (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); FOUN D IN chromatin (ortholog); cytosol (ortholog); euchromatin (ortholog) | | | | Black Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288057134 | dntt.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 16554418 | AL136181.1 | novel transcript, antisense to DNTT | | | | | Human | | name | gene, lncrna |
| 621627 | Dnttip1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | ENCODES a protein that exhibits DNA binding (ortholog); nucleosome binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN chromatin organization (ortholog); FOUND IN chromosome (ortholog); histone deacetylase complex (ortholog); nucleolus (ortholog); INTERACTS WITH 17beta-estr adiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride | 3 | 173901070 | 173924742 | Rat | 79 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1322651 | DNTTIP1 | deoxynucleotidyltransferase terminal interacting protein 1 | DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 20 01 [PubMed 11473582]).[supplied by OMIM, Mar 2008] | 20 | 45791954 | 45811418 | Human | 71 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1322652 | Dnttip1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | Predicted to enable several functions, including enzyme activator activity; nucleosome binding activity; and protein homodimerization activity. Predicted to be located in chromosome; nucleolus; and nucleoplasm. Predicted to be part of histone deacetylase complex. Predicted to be active in nucleus. I s expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human DNTTIP1 (deoxynucleotidyltransferase terminal interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 164587935 | 164610140 | Mouse | 90 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9024573 | Dnttip1 | deoxynucleotidyltransferase terminal interacting protein 1 | ENCODES a protein that exhibits DNA binding (ortholog); nucleosome binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN chromatin organization (ortholog); FOUND IN chromosome (ortholog); histone deacetylase complex (ortholog); nucleolus (ortholog) | NW_004955445 | 11479582 | 11501008 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11944304 | DNTTIP1 | deoxynucleotidyltransferase terminal interacting protein 1 | ENCODES a protein that exhibits DNA binding (inferred); nucleosome binding (inferred); protein homodimerization activity (inferred); INVOLVED IN chromatin organization (inferred); FOUND IN chromosome (inferred); histone deacetylase complex (inferred); nucleolus (inferred) | 20 | 42131601 | 42151047 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12380394 | DNTTIP1 | deoxynucleotidyltransferase terminal interacting protein 1 | ENCODES a protein that exhibits DNA binding (inferred); nucleosome binding (inferred); protein homodimerization activity (inferred); INVOLVED IN chromatin organization (inferred); FOUND IN chromosome (inferred); histone deacetylase complex (inferred); nucleolus (inferred) | 24 | 33102756 | 33127445 | Dog | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12554997 | Dnttip1 | deoxynucleotidyltransferase terminal interacting protein 1 | ENCODES a protein that exhibits DNA binding (inferred); nucleosome binding (inferred); protein homodimerization activity (inferred); INVOLVED IN chromatin organization (inferred); FOUND IN chromosome (inferred); histone deacetylase complex (inferred); nucleolus (inferred) | NW_004936514 | 7209091 | 7231996 | Squirrel | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14114808 | DNTTIP1 | deoxynucleotidyltransferase terminal interacting protein 1 | ENCODES a protein that exhibits DNA binding (inferred); nucleosome binding (inferred); protein homodimerization activity (inferred); INVOLVED IN chromatin organization (inferred); FOUND IN chromosome (inferred); histone deacetylase complex (inferred); nucleolus (inferred) | | | | Pig | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18542848 | DNTTIP1 | deoxynucleotidyltransferase terminal interacting protein 1 | ENCODES a protein that exhibits DNA binding (inferred); nucleosome binding (inferred); protein homodimerization activity (inferred); INVOLVED IN chromatin organization (inferred); FOUND IN chromosome (inferred); histone deacetylase complex (inferred); nucleolus (inferred) | | | | Green Monkey | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932197 | Dnttip1 | deoxynucleotidyltransferase terminal interacting protein 1 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN chromatin organization (ortholog); FOUND IN chromosome (ortholog); histone deacetylase complex (ortholog); nucleolus (ortholog) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155243399 | dnttip1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625853665 | Dnttip1 | deoxynucleotidyltransferase terminal interacting protein 1 | ENCODES a protein that exhibits DNA binding (ortholog); nucleosome binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN chromatin organization (ortholog); FOUND IN chromosome (ortholog); histone deacetylase complex (ortholog); nucleolus (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1319226 | Dnttip2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | Predicted to be involved in RNA processing and ribosomal small subunit biogenesis. Predicted to be located in chromosome and nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in early conceptus and embryo. Orthologous to human DNTT e='font-weight:700;'>DNTTIP2 (deoxynucleotidyltransferase terminal interacting protein 2). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 122068045 | 122078920 | Mouse | 98 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1604625 | DNTTIP2 | deoxynucleotidyltransferase terminal interacting protein 2 | This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a po tential biomarker for chronic obstructive pulmonary disease. [provided by RefSeq, Dec 2010] | 1 | 93866284 | 93879206 | Human | 94 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 6497192 | Dnttip2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | INVOLVED IN ribosomal small subunit biogenesis (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); small-subunit processome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 2 | 213058975 | 213071020 | Rat | 92 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 9063783 | Dnttip2 | deoxynucleotidyltransferase terminal interacting protein 2 | INVOLVED IN ribosomal small subunit biogenesis (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); small-subunit processome (ortholog) | NW_004955423 | 817034 | 828706 | Chinchilla | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11745204 | DNTTIP2 | deoxynucleotidyltransferase terminal interacting protein 2 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (inferred); RNA processing (inferred); FOUND IN nucleolus (inferred); nucleoplasm (inferred); small-subunit processome (inferred) | 1 | 96528951 | 96542869 | Bonobo | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12393517 | DNTTIP2 | deoxynucleotidyltransferase terminal interacting protein 2 | ENCODES a protein that exhibits glutamate-cysteine ligase catalytic subunit binding (inferred); INVOLVED IN glutathione biosynthetic process (inferred); response to oxidative stress (inferred); ribosomal small subunit biogenesis (inferred); FOUND IN glutamate-cysteine ligase complex (inferred); nucl eolus (inferred); nucleoplasm (inferred) | 6 | 55248437 | 55264187 | Dog | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12726859 | Dnttip2 | deoxynucleotidyltransferase terminal interacting protein 2 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (inferred); RNA processing (inferred); FOUND IN nucleolus (inferred); nucleoplasm (inferred); small-subunit processome (inferred) | NW_004936537 | 5381358 | 5391956 | Squirrel | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14248022 | DNTTIP2 | deoxynucleotidyltransferase terminal interacting protein 2 | INVOLVED IN ribosomal small subunit biogenesis (inferred); FOUND IN nucleolus (inferred); nucleoplasm (inferred); small-subunit processome (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 10 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18728420 | DNTTIP2 | deoxynucleotidyltransferase terminal interacting protein 2 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (ortholog); FOUND IN nucleoplasm (ortholog); small-subunit processome (ortholog) | | | | Green Monkey | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921026 | Dnttip2 | deoxynucleotidyltransferase terminal interacting protein 2 | ENCODES a protein that exhibits RNA binding (inferred); transferase activity (inferred); INVOLVED IN ribosomal small subunit biogenesis (ortholog); FOUND IN nucleoplasm (ortholog); small-subunit processome (ortholog) | | | | Naked Mole-Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625858534 | Dnttip2 | deoxynucleotidyltransferase terminal interacting protein 2 | INVOLVED IN ribosomal small subunit biogenesis (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); small-subunit processome (ortholog) | | | | Black Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155243400 | dnttip1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247316 | dnttip1.S | | | | | | African Clawed Frog | | symbol | gene, null |