| 1350551 | DNAJC24 | DnaJ heat shock protein family (Hsp40) member C24 | Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomona s exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008] | 11 | 31369860 | 31432835 | Human | 54 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1558096 | Dnajc24 | DnaJ heat shock protein family (Hsp40) member C24 | Predicted to enable ATPase activator activity; ferrous iron binding activity; and zinc ion binding activity. Involved in protein histidyl modification to diphthamide. Is active in actin cytoskeleton. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human DNAJC24 (DnaJ heat shock protein family (Hsp40) member C24). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 105797053 | 105833894 | Mouse | 64 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1564710 | Dnajc24 | DnaJ heat shock protein family (Hsp40) member C24 | ENCODES a protein that exhibits ATPase activator activity (ortholog); ferrous iron binding (ortholog); zinc ion binding (ortholog); INVOLVED IN positive regulation of ATP-dependent activity (ortholog); protein histidyl modification to diphthamide (ortholog); FOUND IN actin cytoskeleton (ortholog); I NTERACTS WITH bisphenol A; endosulfan; gentamycin | 3 | 112905369 | 112940741 | Rat | 57 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8798891 | Dnajc24 | DnaJ heat shock protein family (Hsp40) member C24 | ENCODES a protein that exhibits ATPase activator activity (ortholog); ferrous iron binding (ortholog); zinc ion binding (ortholog); INVOLVED IN positive regulation of ATP-dependent activity (ortholog); protein histidyl modification to diphthamide (ortholog); FOUND IN actin cytoskeleton (ortholog) | NW_004955476 | 9742909 | 9780321 | Chinchilla | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11712289 | DNAJC24 | DnaJ heat shock protein family (Hsp40) member C24 | ENCODES a protein that exhibits ATPase activator activity (inferred); ferrous iron binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of ATP-dependent activity (ortholog); FOUND IN actin cytoskeleton (inferred); cytoskeleton (inferred) | 11 | 31333447 | 31396852 | Bonobo | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12121791 | DNAJC24 | DnaJ heat shock protein family (Hsp40) member C24 | ENCODES a protein that exhibits ATPase activator activity (ortholog); ferrous iron binding (ortholog); zinc ion binding (ortholog); INVOLVED IN positive regulation of ATP-dependent activity (ortholog); protein histidyl modification to diphthamide (ortholog); FOUND IN actin cytoskeleton (ortholog) | 18 | 35935826 | 36024062 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12480980 | Dnajc24 | DnaJ heat shock protein family (Hsp40) member C24 | ENCODES a protein that exhibits ATPase activator activity (inferred); ferrous iron binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of ATP-dependent activity (ortholog); FOUND IN actin cytoskeleton (inferred); cytoskeleton (inferred) | NW_004936533 | 6289490 | 6340506 | Squirrel | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250211 | dnajc24 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625914070 | Dnajc24 | DnaJ heat shock protein family (Hsp40) member C24 | ENCODES a protein that exhibits ATPase activator activity (ortholog); ferrous iron binding (ortholog); zinc ion binding (ortholog); INVOLVED IN positive regulation of ATP-dependent activity (ortholog); protein histidyl modification to diphthamide (ortholog); FOUND IN actin cytoskeleton (ortholog) | | | | Black Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14024815 | DNAJC24 | DnaJ heat shock protein family (Hsp40) member C24 | ENCODES a protein that exhibits ATPase activator activity (inferred); ferrous iron binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of ATP-dependent activity (ortholog); FOUND IN actin cytoskeleton (inferred); cytoskeleton (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18521956 | DNAJC24 | DnaJ heat shock protein family (Hsp40) member C24 | ENCODES a protein that exhibits ATPase activator activity (inferred); ferrous iron binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of ATP-dependent activity (ortholog); FOUND IN actin cytoskeleton (inferred) | | | | Green Monkey | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909882 | Dnajc24 | DnaJ heat shock protein family (Hsp40) member C24 | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN positive regulation of ATP-dependent activity (ortholog); protein histidyl modification to diphthamide (ortholog); FOUND IN actin cytoskeleton (ortholog) | | | | Naked Mole-Rat | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155249235 | dnajc24.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16559180 | AC005178.1 | DnaJ (Hsp40) homolog, subfamily C, member 24 (DNAJC24) pseudogene | | 5 | 133720495 | 133720934 | Human | | name | gene, pseudo, MODEL [RefSeq] |