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30 records found for search term Dedd
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
620050Dedddeath effector domain-containingENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN spermatogenesis; decidualization (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleolus (ortholog); INTERACTS WITH 1,2-dimethylhydrazine;138628634186301789Rat89symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
731723DEDDdeath effector domain containingThis gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was f1161120974161132667Human92symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1550108Dedddeath effector domain-containingEnables DNA binding activity. Acts upstream of or within decidualization; extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of macromolecule metabolic process. Located in cytoplasm and nucleolus. Is expressed in central nervous system and retina. Orthologous t1171152229171170843Mouse89symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9024537Dedddeath effector domain containingENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN decidualization (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleolus (orthNW_0049554681288554712897522Chinchilla14symbolgene, protein-coding, MODEL [RefSeq]
11928978DEDDdeath effector domain containingENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN decidualization (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (infe1136533756136545107Bonobo25symbolgene, protein-coding, MODEL [RefSeq]
12280515DEDDdeath effector domain containingENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN decidualization (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (infe382134110121351665Dog25symbolgene, protein-coding, MODEL [RefSeq]
12507728Dedddeath effector domain containingENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN decidualization (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (infeNW_004936903436949448670Squirrel25symbolgene, protein-coding, MODEL [RefSeq]
14030210DEDDdeath effector domain containingENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN decidualization (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (infePig25symbolgene, protein-coding, MODEL [RefSeq]
18513373DEDDdeath effector domain containingENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN decidualization (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (infeGreen Monkey25symbolgene, protein-coding, MODEL [RefSeq]
18928157Dedddeath effector domain containingENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN decidualization (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN cytosol (ortholog)Naked Mole-Rat22symbolgene, protein-coding, MODEL [RefSeq]
155244509deddTropical Clawed Frogsymbolgene, null
626161414Dedddeath effector domain containingENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN decidualization (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleolus (orthBlack Rat14symbolgene, protein-coding, MODEL [RefSeq]
155244510dedd.LAfrican Clawed Frogsymbolgene, null
155253784dedd.SAfrican Clawed Frogsymbolgene, null
1597562Dedd-ps1death effector domain-containing, pseudogene 11241178444241180189Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
1353632DEDD2death effector domain containing 2This gene encodes a nuclear-localized protein containing a death effector domain (DED). The encoded protein may regulate the trafficking of caspases and other proteins into the nucleus during death receptor-induced apoptosis. Alternative splicing results in multiple transcript variants. [provided by194219859842220134Human121symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1588968Dedd2death effector domain containing 2ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN apoptotic nuclear changes (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); positive regulation of extrinsic apoptotic signaling pathway (ortholog); FOUND IN nucleolus (ortholog); INTERACTS WIT18991690689934663Rat119symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1615883Dedd2death effector domain-containing DNA binding protein 2Predicted to enable DNA binding activity. Predicted to be involved in apoptotic nuclear changes; extrinsic apoptotic signaling pathway via death domain receptors; and positive regulation of extrinsic apoptotic signaling pathway. Predicted to act upstream of or within apoptotic process and regulation72489933724920035Mouse123symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9052424Dedd2death effector domain containing 2INVOLVED IN apoptotic nuclear changes (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); positive regulation of extrinsic apoptotic signaling pathway (ortholog); FOUND IN nucleolus (ortholog)NW_004955555684523701915Chinchilla5symbolgene, protein-coding, MODEL [RefSeq]
12015357DEDD2death effector domain containing 2ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN apoptotic nuclear changes (inferred); apoptotic process (inferred); DNA-templated transcription (inferred); FOUND IN nucleolus (inferred)193908673539108312Bonobo14symbolgene, protein-coding, MODEL [RefSeq]
12254763DEDD2death effector domain containing 2ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN apoptotic nuclear changes (inferred); apoptotic process (inferred); DNA-templated transcription (inferred); FOUND IN nucleolus (inferred)1112148146112164473Dog14symbolgene, protein-coding, MODEL [RefSeq]
12716052Dedd2death effector domain containing 2ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN apoptotic nuclear changes (inferred); apoptotic process (inferred); DNA-templated transcription (inferred); FOUND IN nucleolus (inferred)NW_004936706285874302910Squirrel14symbolgene, protein-coding, MODEL [RefSeq]
13962817DEDD2death effector domain containing 2ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN apoptotic nuclear changes (inferred); apoptotic process (inferred); DNA-templated transcription (inferred); FOUND IN nucleolus (inferred)Pig14symbolgene, protein-coding, MODEL [RefSeq]
18746611DEDD2death effector domain containing 2ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN apoptotic nuclear changes (inferred); apoptotic process (inferred); DNA-templated transcription (inferred); FOUND IN nucleolus (inferred)Green Monkey14symbolgene, protein-coding, MODEL [RefSeq]
18915003Dedd2death effector domain containing 2ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN apoptotic nuclear changes (inferred); apoptotic process (inferred); DNA-templated transcription (inferred); FOUND IN nucleolus (inferred)Naked Mole-Rat14symbolgene, protein-coding, MODEL [RefSeq]
155246072dedd2Tropical Clawed Frogsymbolgene, null
626085547Dedd2death effector domain containing 2INVOLVED IN apoptotic nuclear changes (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); positive regulation of extrinsic apoptotic signaling pathway (ortholog); FOUND IN nucleolus (ortholog)Black Rat5symbolgene, protein-coding, MODEL [RefSeq]
155259149dedd2.LAfrican Clawed Frogsymbolgene, null
155246073dedd2.SAfrican Clawed Frogsymbolgene, null
1313479TRRAPtransformation/transcription domain associated proteinThis gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregul79887853299013241Human238old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]