Cyth4 Gene Search Result

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12 records found for search term Cyth4

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1345777	CYTH4	cytohesin 4	This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) ac ... (more) tivity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]	22	37282508	37315341	Human	95	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1557551	Cyth4	cytohesin 4	Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Predicted to be located in several cellular components, including centriolar satellite; cytosol; and intercellular bridge. Is expressed in brain. Orthologous to ... (more) human CYTH4 (cytohesin 4). [provided by Alliance of Genome Resources, Jul 2025]	15	78481247	78506219	Mouse	107	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1564842	Cyth4	cytohesin 4	ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN regulation of ARF protein signal transduction (inferred); FOUND IN plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine	7	112032711	112057204	Rat	93	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
9013067	Cyth4	cytohesin 4	ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); FOUND IN plasma membrane (ortholog)	NW_004955413	23745797	23774397	Chinchilla	6	symbol	gene, protein-coding, MODEL [RefSeq]
11935696	CYTH4	cytohesin 4	ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN regulation of ARF protein signal transduction (inferred); FOUND IN Golgi membrane (inferred); plasma membrane (inferred)	22	18197307	18230274	Bonobo	9	symbol	gene, protein-coding, MODEL [RefSeq]
12392178	CYTH4	cytohesin 4	ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); lipid binding (inferred); INVOLVED IN regulation of ARF protein signal transduction (inferred); FOUND IN plasma membrane (inferred)	10	27238028	27268759	Dog	14	symbol	gene, protein-coding, MODEL [RefSeq]
12606659	Cyth4	cytohesin 4	ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN regulation of ARF protein signal transduction (inferred); FOUND IN plasma membrane (inferred)	NW_004936492	3678299	3703787	Squirrel	8	symbol	gene, protein-coding, MODEL [RefSeq]
18910495	Cyth4	cytohesin 4	ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); lipid binding (inferred); INVOLVED IN regulation of ARF protein signal transduction (inferred); FOUND IN plasma membrane (inferred)				Naked Mole-Rat	9	symbol	gene, protein-coding, MODEL [RefSeq]
155242977	cyth4						Tropical Clawed Frog		symbol	gene, null
14270818	CYTH4	cytohesin 4	ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); lipid binding (inferred); INVOLVED IN regulation of ARF protein signal transduction (inferred); FOUND IN plasma membrane (inferred)				Pig	14	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
18644765	CYTH4	cytohesin 4	ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); lipid binding (inferred); INVOLVED IN regulation of ARF protein signal transduction (inferred); FOUND IN cytoplasm (inferred); Golgi membrane (inferred); plasma membrane (inferred)				Green Monkey	13	symbol	gene, protein-coding, MODEL [RefSeq]
155233615	cyth4.L						African Clawed Frog		symbol	gene, null