| 1345048 | CXXC5 | CXXC finger protein 5 | The protein encoded by this gene is a retinoid-inducible nuclear protein containing a CXXC-type zinc finger motif. The encoded protein is involved in myelopoiesis, is required for DNA damage-induced p53 activation, regulates the differentiation of C2C12 myoblasts into myocytes, and negatively regula tes cutaneous wound healing. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015] | 5 | 139647299 | 139683882 | Human | 159 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1359466 | Cxxc5 | CXXC finger protein 5 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); methyl-CpG binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of canonical NF-kappaB signal transducti on (ortholog); regulation of generation of precursor metabolites and energy (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione | 18 | 27701650 | 27732633 | Rat | 162 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1553694 | Cxxc5 | CXXC finger 5 | Predicted to enable DNA-binding transcription factor binding activity; methyl-CpG binding activity; and zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and regulation of generation of precursor metabolites and energy. Predicted to be l ocated in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human CXXC5 (CXXC finger protein 5). [provided by Alliance of Genome Resources, Jul 2025] | 18 | 35962432 | 35994746 | Mouse | 195 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8781423 | Cxxc5 | CXXC finger protein 5 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); methyl-CpG binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of canonical NF-kappaB signal transducti on (ortholog); regulation of generation of precursor metabolites and energy (ortholog); FOUND IN nucleoplasm (ortholog) | NW_004955418 | 932198 | 965894 | Chinchilla | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11745906 | CXXC5 | CXXC finger protein 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 5 | 135015148 | 135050736 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12331979 | CXXC5 | CXXC finger protein 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor binding (inferred); guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (infer red); nucleus (inferred) | 2 | 34903680 | 34939580 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12535110 | Cxxc5 | CXXC finger protein 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936531 | 8707201 | 8739647 | Squirrel | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625853941 | Cxxc5 | CXXC finger protein 5 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); methyl-CpG binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of canonical NF-kappaB signal transducti on (ortholog); regulation of generation of precursor metabolites and energy (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Black Rat | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18345783 | CXXC5 | CXXC finger protein 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18913219 | Cxxc5 | CXXC finger protein 5 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); regulation of ge neration of precursor metabolites and energy (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13872621 | CXXC5 | CXXC finger protein 5 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13210587 | CXXC5-AS1 | CXXC5 antisense RNA 1 | | 5 | 139648999 | 139649728 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1596788 | Cxxc5l1 | CXXC finger protein 5 like 1 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); FOUND IN cytoplasm (inferred); nucleus (inferred) | X | 131769118 | 131770604 | Rat | 9 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |