| 2407 | Crmp1 | collapsin response mediator protein 1 | ENCODES a protein that exhibits filamin binding (ortholog); identical protein binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN neuron development; negative regulation of neuron projection development (ortholog); regulation of postsynapse assembly (ortholog); FOUND IN actin cytoskel eton (ortholog); centrosome (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 77734675 | 77780916 | Rat | 129 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 10395 | Crmp1 | collapsin response mediator protein 1 | This gene encodes a protein that is part of the collapsin response mediator protein family. The family is comprised of five, homologous cytosolic phosphoproteins that are expressed in developing and adult nervous tissue and mediate signaling to transduce responses to extracellular cues. This protein is a Semaphorin 3A signaling molecule that regulates collapse of the growth cone. The growth cone mediates axonal pathfinding in neurons. This protein is reported to represent a new class of microtubule-associated proteins. In humans this protein is reported to inhibit cancer cell invasion. In mouse deficiency of this gene may be associated with impaired spatial memory performance. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013] | 5 | 37399402 | 37449507 | Mouse | 145 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 731741 | CRMP1 | collapsin response mediator protein 1 | This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative spli cing results in multiple transcript variants. [provided by RefSeq, Jul 2008] | 4 | 5820764 | 5893086 | Human | 121 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8811564 | Crmp1 | collapsin response mediator protein 1 | ENCODES a protein that exhibits filamin binding (ortholog); identical protein binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN negative regulation of neuron projection development (ortholog); neuron development (ortholog); regulation of postsynapse assembly (ortholog); FOUND IN act in cytoskeleton (ortholog); centrosome (ortholog); cytosol (ortholog) | NW_004955514 | 4216575 | 4273947 | Chinchilla | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12163190 | CRMP1 | collapsin response mediator protein 1 | ENCODES a protein that exhibits filamin binding (inferred); hydrolase activity (inferred); hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (inferred); INVOLVED IN neuron development (ortholog); FOUND IN actin cytoskeleton (inferred); centrosome (inferred); cytoplasm (inferred) | 3 | 71009382 | 71077814 | Dog | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12736709 | Crmp1 | collapsin response mediator protein 1 | ENCODES a protein that exhibits filamin binding (inferred); hydrolase activity (inferred); hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (inferred); INVOLVED IN neuron development (ortholog); FOUND IN actin cytoskeleton (inferred); centrosome (inferred); cytoplasm (inferred) | NW_004936477 | 17997213 | 18035266 | Squirrel | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18400078 | CRMP1 | collapsin response mediator protein 1 | ENCODES a protein that exhibits filamin binding (inferred); hydrolase activity (inferred); hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (inferred); INVOLVED IN neuron development (ortholog); FOUND IN actin cytoskeleton (inferred); centrosome (inferred); cytoplasm (inferred) | | | | Green Monkey | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14177834 | CRMP1 | collapsin response mediator protein 1 | ENCODES a protein that exhibits filamin binding (inferred); hydrolase activity (inferred); hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (inferred); INVOLVED IN neuron development (ortholog); FOUND IN actin cytoskeleton (inferred); centrosome (inferred); cytoplasm (inferred) | | | | Pig | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18933001 | Crmp1 | collapsin response mediator protein 1 | ENCODES a protein that exhibits filamin binding (ortholog); identical protein binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN negative regulation of neuron projection development (ortholog); neuron development (ortholog); regulation of postsynapse assembly (ortholog); FOUND IN act in cytoskeleton (ortholog); dendrite (ortholog); growth cone (ortholog) | | | | Naked Mole-Rat | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626051816 | Crmp1 | collapsin response mediator protein 1 | ENCODES a protein that exhibits filamin binding (ortholog); identical protein binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN negative regulation of neuron projection development (ortholog); neuron development (ortholog); regulation of postsynapse assembly (ortholog); FOUND IN act in cytoskeleton (ortholog); centrosome (ortholog); cytosol (ortholog) | | | | Black Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11848085 | CRMP1 | collapsin response mediator protein 1 | ENCODES a protein that exhibits filamin binding (inferred); hydrolase activity (inferred); hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (inferred); INVOLVED IN neuron development (ortholog); FOUND IN actin cytoskeleton (inferred); centrosome (inferred); cytoplasm (inferred) | | | | Bonobo | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155253815 | crmp1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155249726 | crmp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247473 | crmp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
