| 1309502 | Crebl2 | cAMP responsive element binding protein-like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of D-glucose import across plasma membrane (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of fat cell differen tiation (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 4 | 169404630 | 169430618 | Rat | 87 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1319876 | CREBL2 | cAMP responsive element binding protein like 2 | cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non- small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008] | 12 | 12611876 | 12645108 | Human | 87 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1615677 | Crebl2 | cAMP responsive element binding protein-like 2 | Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Involved in several processes, including positive regulation of D-glucose import; positive regulation of metabolic process; and protein stabilization. Located in nucleus. Orthologous to human CREBL2 ight:700;'>CREBL2 (cAMP responsive element binding protein like 2). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 134807090 | 134835894 | Mouse | 78 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8781541 | Crebl2 | cAMP responsive element binding protein like 2 | INVOLVED IN positive regulation of D-glucose import across plasma membrane (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of fat cell differentiation (ortholog); FOUND IN nucleus (ortholog) | NW_004955413 | 9513625 | 9535817 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11928612 | CREBL2 | cAMP responsive element binding protein like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of D-glucose import across plasma membrane (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of fat cell differen tiation (ortholog); FOUND IN nucleus (inferred) | 12 | 12632763 | 12665646 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12364821 | CREBL2 | cAMP responsive element binding protein like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of D-glucose import across plasma membrane (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of fat cell differen tiation (ortholog); FOUND IN nucleus (inferred) | 27 | 33684376 | 33711625 | Dog | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12516150 | Crebl2 | cAMP responsive element binding protein like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of D-glucose import across plasma membrane (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of fat cell differen tiation (ortholog); FOUND IN nucleus (inferred) | NW_004936587 | 4645507 | 4663920 | Squirrel | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155235434 | crebl2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18912507 | Crebl2 | cAMP responsive element binding protein like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of D-glucose import across plasma membrane (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of fat cell differen tiation (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18654974 | CREBL2 | cAMP responsive element binding protein like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of D-glucose import across plasma membrane (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of fat cell differen tiation (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626090205 | Crebl2 | cAMP responsive element binding protein like 2 | INVOLVED IN positive regulation of D-glucose import across plasma membrane (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of fat cell differentiation (ortholog); FOUND IN nucleus (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14242917 | CREBL2 | cAMP responsive element binding protein like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of D-glucose import across plasma membrane (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of fat cell differen tiation (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155235388 | crebl2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155235435 | crebl2.S | | | | | | African Clawed Frog | | symbol | gene, null |
