Col18a1 Gene Search Result

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

Genes search result for All species
(View Results for all Objects and Ontologies)

17 records found for search term Col18a1

Refine Term:

Sort By:

Export

RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
70936	Col18a1	collagen type XVIII alpha 1 chain	ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN response to hydrostatic pressure; response to xenobiotic stimulus; angiogenesis (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Colonic Neoplasms; Experimental Mammary Neoplasms; Fibrosi ... (more) s; FOUND IN extracellular space; basement membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl	20	11473645	11582111	Rat	279	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
736032	COL18A1	collagen type XVIII alpha 1 chain	This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is ho ... (more) mologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]	21	45405165	45513720	Human	427	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
736033	Col18a1	collagen, type XVIII, alpha 1	Predicted to enable identical protein binding activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Acts upstream of or within several processes, including endothelial cell morphogenesis; positive regulation of endothelial cell apoptotic process; and p ... (more) ositive regulation of vascular endothelial cell proliferation. Located in basement membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study pigment dispersion syndrome. Human ortholog(s) of this gene implicated in primary angle-closure glaucoma. Orthologous to human COL18A1 (collagen type XVIII alpha 1 chain). [provided by Alliance of Genome Resources, Jul 2025]	10	76888013	77002351	Mouse	333	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8843833	Col18a1	collagen type XVIII alpha 1 chain	ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); endothelial cell morphogenesis (ortholog); extracellular matrix organization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH angiosarcoma (ortholog); calcinosis ... (more) (ortholog); cataract (ortholog); FOUND IN basement membrane (ortholog); extracellular space (ortholog)	NW_004955407	42091211	42131343	Chinchilla	39	symbol	gene, protein-coding, MODEL [RefSeq]
11673127	COL18A1	collagen type XVIII alpha 1 chain	ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); endothelial cell morphogenesis (ortholog); extracellular matrix organization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH angiosarcoma (ortholog); calcinosis ... (more) (ortholog); cataract (ortholog); FOUND IN basement membrane (ortholog); extracellular space (ortholog)	21	31720358	31834470	Bonobo	39	symbol	gene, protein-coding, MODEL [RefSeq]
12355212	COL18A1	collagen type XVIII alpha 1 chain	ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); endothelial cell morphogenesis (ortholog); extracellular matrix organization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH angiosarcoma (ortholog); calcinosis ... (more) (ortholog); cataract (ortholog); FOUND IN extracellular space (ortholog)	31	38915872	38957484	Dog	49	symbol	gene, protein-coding, MODEL [RefSeq]
12533170	Col18a1	collagen type XVIII alpha 1 chain	ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); endothelial cell morphogenesis (ortholog); extracellular matrix organization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH angiosarcoma (ortholog); calcinosis ... (more) (ortholog); cataract (ortholog); FOUND IN extracellular space (ortholog)	NW_004936778	847473	943038	Squirrel	47	symbol	gene, protein-coding, MODEL [RefSeq]
18926506	Col18a1	collagen type XVIII alpha 1 chain	ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); endothelial cell morphogenesis (ortholog); extracellular matrix organization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH angiosarcoma (ortholog); calcinosis ... (more) (ortholog); cataract (ortholog); FOUND IN extracellular space (ortholog)				Naked Mole-Rat	43	symbol	gene, protein-coding, MODEL [RefSeq]
15039232	COL18A1	collagen, type XVIII, alpha 1	INVOLVED IN cell adhesion (inferred)				Pig	1	symbol	gene, protein-coding
18590719	COL18A1	collagen type XVIII alpha 1 chain	ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); endothelial cell morphogenesis (ortholog); extracellular matrix organization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH angiosarcoma (ortholog); calcinosis ... (more) (ortholog); cataract (ortholog); FOUND IN basement membrane (ortholog); extracellular space (ortholog)				Green Monkey	39	symbol	gene, protein-coding, MODEL [RefSeq]
626089486	Col18a1	collagen type XVIII alpha 1 chain	ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); endothelial cell morphogenesis (ortholog); extracellular matrix organization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH angiosarcoma (ortholog); calcinosis ... (more) (ortholog); cataract (ortholog); FOUND IN basement membrane (ortholog); extracellular space (ortholog)				Black Rat	39	symbol	gene, protein-coding, MODEL [RefSeq]
155233803	col18a1						Tropical Clawed Frog		symbol	gene, null
13902912	COL18A1	collagen type XVIII alpha 1 chain	ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); endothelial cell morphogenesis (ortholog); extracellular matrix organization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH angiosarcoma (ortholog); calcinosis ... (more) (ortholog); cataract (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH deoxynivalenol				Pig	50	symbol	gene, protein-coding, MODEL [RefSeq]
155236493	col18a1.L						African Clawed Frog		symbol	gene, null
155233802	col18a1.S						African Clawed Frog		symbol	gene, null
1350562	COL18A1-AS1	COL18A1 antisense RNA 1	INTERACTS WITH 17beta-estradiol; valproic acid	21	45419716	45425070	Human	2	symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
6766705	COL18A1-AS2	COL18A1 antisense RNA 2	INTERACTS WITH aflatoxin B1; benzo[a]pyrene; benzo[e]pyrene	21	45407386	45410065	Human	4	symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]