| 1309083 | Clspn | claspin | ENCODES a protein that exhibits anaphase-promoting complex binding (ortholog); DNA secondary structure binding (ortholog); INVOLVED IN DNA damage checkpoint signaling (ortholog); DNA replication checkpoint signaling (ortholog); mitotic DNA replication checkpoint signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); myoepithelioma (ortholog); FOUND IN Golgi apparatus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 5 | 144134619 | 144169531 | Rat | 133 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1319224 | CLSPN | claspin | The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants enco ding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] | 1 | 35720213 | 35769978 | Human | 133 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1620487 | Clspn | claspin | Predicted to enable DNA secondary structure binding activity and anaphase-promoting complex binding activity. Predicted to be involved in activation of protein kinase activity; mitotic G2/M transition checkpoint; and peptidyl-serine phosphorylation. Predicted to be located in Golgi apparatus and nuc leoplasm. Is expressed in several structures, including alimentary system; brain ventricular layer; endocrine gland; genitourinary system; and immune system. Orthologous to human CLSPN (claspin). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 126450738 | 126488326 | Mouse | 169 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9001933 | Clspn | claspin | ENCODES a protein that exhibits anaphase-promoting complex binding (ortholog); DNA secondary structure binding (ortholog); INVOLVED IN DNA damage checkpoint signaling (ortholog); DNA replication checkpoint signaling (ortholog); mitotic DNA replication checkpoint signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); myoepithelioma (ortholog); FOUND IN Golgi apparatus (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955452 | 13801073 | 13842387 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12045406 | CLSPN | claspin | ENCODES a protein that exhibits anaphase-promoting complex binding (inferred); DNA secondary structure binding (inferred); INVOLVED IN DNA replication checkpoint signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); myoepithelioma (ortholog); FOUND IN Golgi apparatus (inferred); nucleoplasm (in ferred); nucleus (inferred) | 1 | 34991082 | 35040515 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12137878 | CLSPN | claspin | ENCODES a protein that exhibits anaphase-promoting complex binding (inferred); DNA secondary structure binding (inferred); INVOLVED IN DNA replication checkpoint signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); myoepithelioma (ortholog); FOUND IN Golgi apparatus (inferred); nucleoplasm (in ferred); nucleus (inferred); INTERACTS WITH bisphenol A | 15 | 6400084 | 6430295 | Dog | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12487765 | Clspn | claspin | ENCODES a protein that exhibits anaphase-promoting complex binding (inferred); DNA secondary structure binding (inferred); INVOLVED IN DNA replication checkpoint signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); myoepithelioma (ortholog); FOUND IN Golgi apparatus (inferred); nucleoplasm (in ferred); nucleus (inferred) | NW_004936474 | 18267740 | 18304658 | Squirrel | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14158247 | CLSPN | claspin | ENCODES a protein that exhibits anaphase-promoting complex binding (inferred); DNA secondary structure binding (inferred); INVOLVED IN DNA replication checkpoint signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); myoepithelioma (ortholog); FOUND IN Golgi apparatus (inferred); nucleoplasm (in ferred); nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155247262 | clspn | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18765639 | CLSPN | claspin | ENCODES a protein that exhibits DNA secondary structure binding (ortholog); INVOLVED IN DNA damage checkpoint signaling (ortholog); DNA replication checkpoint signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); myoepithelioma (ortholog); FOUND IN Golgi apparatus (ortholog); nucleoplasm (ortho log) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626098783 | Clspn | claspin | ENCODES a protein that exhibits anaphase-promoting complex binding (ortholog); DNA secondary structure binding (ortholog); INVOLVED IN DNA damage checkpoint signaling (ortholog); DNA replication checkpoint signaling (ortholog); mitotic DNA replication checkpoint signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); myoepithelioma (ortholog); FOUND IN Golgi apparatus (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18935710 | Clspn | claspin | ENCODES a protein that exhibits DNA secondary structure binding (ortholog); INVOLVED IN DNA damage checkpoint signaling (ortholog); DNA replication checkpoint signaling (ortholog); ASSOCIATED WITH COVID-19 (ortholog); myoepithelioma (ortholog); FOUND IN Golgi apparatus (ortholog); nucleoplasm (ortho log) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 596934402 | clspn.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155240709 | clspn.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934413 | clspn.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596936038 | clspn.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596933621 | clspn.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155246163 | clspn.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 597621560 | CLSPN-DT | CLSPN divergent transcript | | 1 | 35770095 | 35806940 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 597621570 | CLSPN-AS1 | CLSPN antisense RNA 1 | | 1 | 35739445 | 35743576 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
