| 1308837 | Cldn6 | claudin 6 | ENCODES a protein that exhibits virus receptor activity (ortholog); INVOLVED IN cell-cell junction organization (ortholog); PARTICIPATES IN hepatitis C pathway; FOUND IN apicolateral plasma membrane (ortholog); bicellular tight junction (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphth yl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | 10 | 13213837 | 13218578 | Rat | 111 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1318839 | CLDN6 | claudin 6 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of cont inuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010] | 16 | 3014712 | 3018183 | Human | 111 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1318840 | Cldn6 | claudin 6 | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cel l sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is essential for blastocyst formation in preimplantation mouse embryos, and is invloved in and is crucial for the formation and maintenance of the epidermal permeability barrier. This gene is adjacent to another family member Cldn9 on chromosome 17. [provided by RefSeq, Aug 2010] | 17 | 23898345 | 23901417 | Mouse | 122 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 8889668 | Cldn6 | claudin 6 | ENCODES a protein that exhibits virus receptor activity (ortholog); INVOLVED IN cell-cell junction organization (ortholog); FOUND IN apicolateral plasma membrane (ortholog); bicellular tight junction (ortholog); plasma membrane (ortholog) | NW_004955442 | 14323193 | 14326311 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11692253 | CLDN6 | claudin 6 | ENCODES a protein that exhibits virus receptor activity (ortholog); INVOLVED IN cell-cell junction organization (ortholog); FOUND IN apicolateral plasma membrane (ortholog); bicellular tight junction (ortholog); plasma membrane (ortholog) | 16 | 1956556 | 1960177 | Bonobo | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12420544 | CLDN6 | claudin 6 | ENCODES a protein that exhibits structural molecule activity (inferred); virus receptor activity (inferred); INVOLVED IN cell-cell junction organization (ortholog); FOUND IN apicolateral plasma membrane (inferred); bicellular tight junction (inferred); membrane (inferred) | 6 | 38168793 | 38171827 | Dog | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12712460 | Cldn6 | claudin 6 | ENCODES a protein that exhibits structural molecule activity (inferred); virus receptor activity (inferred); INVOLVED IN cell-cell junction organization (ortholog); FOUND IN apicolateral plasma membrane (inferred); bicellular tight junction (inferred); membrane (inferred) | NW_004936694 | 1153189 | 1154012 | Squirrel | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626000970 | Cldn6 | claudin 6 | ENCODES a protein that exhibits virus receptor activity (ortholog); INVOLVED IN cell-cell junction organization (ortholog); FOUND IN apicolateral plasma membrane (ortholog); bicellular tight junction (ortholog); plasma membrane (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 150657578 | CLDN6 | claudin 6 | ENCODES a protein that exhibits structural molecule activity (inferred); virus receptor activity (inferred); INVOLVED IN cell-cell adhesion (inferred); symbiont entry into host cell (inferred); FOUND IN apicolateral plasma membrane (inferred); bicellular tight junction (inferred); membrane (inferred ) | | | | Dog | 19 | symbol | gene, protein-coding |
| 14079777 | CLDN6 | claudin 6 | ENCODES a protein that exhibits structural molecule activity (inferred); virus receptor activity (inferred); INVOLVED IN cell-cell junction organization (ortholog); FOUND IN apicolateral plasma membrane (inferred); bicellular tight junction (inferred); membrane (inferred); INTERACTS WITH deoxynivale nol | | | | Pig | 25 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18563612 | CLDN6 | claudin 6 | ENCODES a protein that exhibits structural molecule activity (inferred); virus receptor activity (inferred); INVOLVED IN cell-cell junction organization (ortholog); FOUND IN apicolateral plasma membrane (inferred); bicellular tight junction (inferred); membrane (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18928670 | Cldn6 | claudin 6 | ENCODES a protein that exhibits structural molecule activity (inferred); virus receptor activity (inferred); INVOLVED IN cell-cell junction organization (ortholog); FOUND IN apicolateral plasma membrane (inferred); bicellular tight junction (inferred); membrane (inferred) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155251769 | cldn6.1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 285895708 | cldn6.2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155257964 | cldn6.1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155256939 | cldn6.1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 288057277 | cldn6.2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 329329194 | cldn6.2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16552610 | AL353807.1 | claudin 6 (CLDN6) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16563559 | AC004233.1 | novel transcript, sense overlapping CLDN6 | | | | | Human | | name | gene, lncrna |
