| 1312617 | CENPH | centromere protein H | Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of cen tromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. [provided by RefSeq, Jul 2008] | 5 | 69189583 | 69210357 | Human | 126 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312618 | Cenph | centromere protein H | Enables kinetochore binding activity. Predicted to be involved in chromosome segregation and mitotic spindle organization. Predicted to act upstream of or within mitotic cell cycle. Located in kinetochore and nucleus. Is expressed in several structures, including brain; genitourinary system; gut; he molymphoid system gland; and skin. Orthologous to human CENPH (centromere protein H). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 100896187 | 100912415 | Mouse | 129 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1583506 | Cenph | centromere protein H | ENCODES a protein that exhibits kinetochore binding (ortholog); INVOLVED IN kinetochore assembly (inferred); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN chromosome (ortholog); kinetochore (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodib enzodioxine; Cuprizon | 2 | 33630738 | 33644258 | Rat | 121 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 8926604 | Cenph | centromere protein H | ENCODES a protein that exhibits kinetochore binding (ortholog); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN chromosome (ortholog); kinetochore (ortholog); nucleoplasm (ortholog) | NW_004955446 | 131703 | 135873 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11900498 | CENPH | centromere protein H | ENCODES a protein that exhibits kinetochore binding (inferred); INVOLVED IN chromosome segregation (inferred); kinetochore assembly (inferred); mitotic spindle organization (inferred); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN chromosome (inferred); kinetochore (inferred); nucleoplasm (inferred) | 5 | 44793303 | 44814297 | Bonobo | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12131706 | CENPH | centromere protein H | ENCODES a protein that exhibits kinetochore binding (inferred); INVOLVED IN kinetochore assembly (inferred); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN chromosome (inferred); kinetochore (inferred); nucleoplasm (inferred) | 2 | 54267782 | 54299083 | Dog | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12540767 | Cenph | centromere protein H | ENCODES a protein that exhibits kinetochore binding (inferred); INVOLVED IN chromosome segregation (inferred); kinetochore assembly (inferred); mitotic spindle organization (inferred); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN chromosome (inferred); kinetochore (inferred); nucleoplasm (inferred) | NW_004936480 | 379172 | 396167 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867191 | CENPH | centromere protein H | ENCODES a protein that exhibits kinetochore binding (inferred); INVOLVED IN chromosome segregation (inferred); kinetochore assembly (inferred); mitotic spindle organization (inferred); FOUND IN chromosome (inferred); kinetochore (inferred); nucleoplasm (inferred) | | | | Green Monkey | 14 | symbol | gene, protein-coding |
| 18910605 | Cenph | centromere protein H | ENCODES a protein that exhibits kinetochore binding (inferred); INVOLVED IN chromosome segregation (inferred); kinetochore assembly (inferred); mitotic spindle organization (inferred); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN chromosome (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14202354 | CENPH | centromere protein H | ENCODES a protein that exhibits kinetochore binding (inferred); INVOLVED IN kinetochore assembly (inferred); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN chromosome (inferred); kinetochore (inferred); nucleoplasm (inferred) | | | | Pig | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625911454 | Cenph | centromere protein H | ENCODES a protein that exhibits kinetochore binding (ortholog); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN chromosome (ortholog); kinetochore (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18409731 | CENPH | centromere protein H | ENCODES a protein that exhibits kinetochore binding (ortholog); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN chromosome (ortholog); kinetochore (ortholog); nucleoplasm (ortholog) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288067416 | cenph | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 329332908 | cenph.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1605966 | CENPK | centromere protein K | CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied b y OMIM, Mar 2008] | 5 | 65495624 | 65563168 | Human | 131 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1605310 | CENPL | centromere protein L | CENPL is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006) [PubMed 16622420].[supplied b y OMIM, Mar 2008] | 1 | 173799550 | 173824883 | Human | 81 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1603809 | CENPP | centromere protein P | CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied b y OMIM, Mar 2008] | 9 | 92325468 | 92620529 | Human | 77 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1344338 | CENPQ | centromere protein Q | CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied b y OMIM, Mar 2008] | 6 | 49463370 | 49493107 | Human | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |