| 620002 | Cdk5rap3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits protein-containing complex binding; cyclin binding (ortholog); MDM2/MDM4 family protein binding (ortholog); INVOLVED IN negative regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of cyclin-dependent protein serine/threonine kinase act ivity; apoptotic nuclear changes (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 82390845 | 82402814 | Rat | 199 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 731437 | CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing result s in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013] | 17 | 47967904 | 47981781 | Human | 156 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1616671 | Cdk5rap3 | CDK5 regulatory subunit associated protein 3 | Enables ubiquitin-like protein ligase binding activity. Involved in several processes, including definitive erythrocyte differentiation; liver development; and protein ufmylation. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm. Is expressed in several structures, including brain; hemolymphoid system gland; liver; retina; and seminiferous cord. Orthologous to human CDK5RAP3 (CDK5 regulatory subunit associated protein 3). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 96798251 | 96807359 | Mouse | 234 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8726125 | Cdk5rap3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits cyclin binding (ortholog); MDM2/MDM4 family protein binding (ortholog); mitogen-activated protein kinase binding (ortholog); INVOLVED IN apoptotic nuclear changes (ortholog); cell population proliferation (ortholog); definitive erythrocyte differentiation (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955451 | 13160811 | 13170012 | Chinchilla | 63 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11753825 | CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits cyclin binding (ortholog); MDM2/MDM4 family protein binding (ortholog); mitogen-activated protein kinase binding (ortholog); INVOLVED IN apoptotic nuclear changes (ortholog); cell population proliferation (ortholog); definitive erythrocyte differentiation (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | 17 | 9556313 | 9567099 | Bonobo | 65 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12063515 | CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); negative regulation of MAP kinase activity (ortholog); negative regulation of protein kinase activity by regulation of protein phosphorylation (ortholog); FOUND IN nucleolus (ortholog) | 9 | 24276660 | 24286273 | Dog | 60 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12531466 | Cdk5rap3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); negative regulation of MAP kinase activity (ortholog); negative regulation of protein kinase activity by regulation of protein phosphorylation (ortholog); FOUND IN nucleolus (ortholog) | NW_004936490 | 13345443 | 13355841 | Squirrel | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626084248 | Cdk5rap3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits cyclin binding (ortholog); MDM2/MDM4 family protein binding (ortholog); mitogen-activated protein kinase binding (ortholog); INVOLVED IN apoptotic nuclear changes (ortholog); cell population proliferation (ortholog); definitive erythrocyte differentiation (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | | | | Black Rat | 63 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14057245 | CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); negative regulation of MAP kinase activity (ortholog); negative regulation of protein kinase activity by regulation of protein phosphorylation (ortholog); FOUND IN nucleolus (ortholog) | | | | Pig | 60 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18672660 | CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); negative regulation of MAP kinase activity (ortholog); negative regulation of protein kinase activity by regulation of protein phosphorylation (ortholog); FOUND IN nucleolus (ortholog) | | | | Green Monkey | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18912812 | Cdk5rap3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits cyclin binding (ortholog); MDM2/MDM4 family protein binding (ortholog); mitogen-activated protein kinase binding (ortholog); INVOLVED IN apoptotic nuclear changes (ortholog); cell population proliferation (ortholog); definitive erythrocyte differentiation (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | | | | Naked Mole-Rat | 65 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242900 | cdk5rap3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155242901 | cdk5rap3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247354 | cdk5rap3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16552949 | CDK5RAP3P1 | CDK5RAP3 pseudogene 1 | | 20 | 31285049 | 31286865 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16563958 | AC018521.4 | novel transcript, antisense to CDK5RAP3 | | | | | Human | | name | gene, lncrna |
| 1319587 | UFL1 | UFM1 specific ligase 1 | Enables UFM1 ligase activity and protein kinase binding activity. Involved in several processes, including positive regulation of reticulophagy; regulation of intracellular signal transduction; and regulation of primary metabolic process. Acts upstream of or within several processes, including posit ive regulation of cell population proliferation; regulation of proteasomal ubiquitin-dependent protein catabolic process; and response to endoplasmic reticulum stress. Located in cytoplasm; nucleus; and site of double-strand break. Part of protein-containing complex. Is active in endoplasmic reticulum membrane and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Jul 2025] | 6 | 96521806 | 96555276 | Human | 136 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |