| 1309088 | Cbfa2t2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | ENCODES a protein that exhibits transcription corepressor activity (ortholog); INVOLVED IN epithelial cell differentiation (ortholog); intestinal epithelial cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3 ,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 3 | 163397160 | 163503409 | Rat | 86 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1319231 | CBFA2T2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimer ic protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. [provided by RefSeq, Jul 2008] | 20 | 33490096 | 33650030 | Human | 90 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1619284 | Cbfa2t2 | CBFA2/RUNX1 translocation partner 2 | Enables transcription corepressor activity. Involved in intestinal epithelial cell differentiation and negative regulation of Notch signaling pathway. Acts upstream of or within epithelial cell differentiation and negative regulation of transcription by RNA polymerase II. Predicted to be active in n ucleus. Is expressed in several structures, including alimentary system; blastocyst; brain; genitourinary system; and sensory organ. Orthologous to human CBFA2T2 (CBFA2/RUNX1 partner transcriptional co-repressor 2). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 154278018 | 154381276 | Mouse | 116 | symbol , old_gene_name , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8958915 | Cbfa2t2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | ENCODES a protein that exhibits transcription corepressor activity (ortholog); INVOLVED IN epithelial cell differentiation (ortholog); intestinal epithelial cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN nucleus (ortholog) | NW_004955422 | 27671215 | 27809384 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11873440 | CBFA2T2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | ENCODES a protein that exhibits metal ion binding (inferred); transcription corepressor activity (inferred); zinc ion binding (inferred); INVOLVED IN epithelial cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (inferred) | 20 | 29780902 | 29937398 | Bonobo | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12380356 | CBFA2T2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | ENCODES a protein that exhibits metal ion binding (inferred); transcription corepressor activity (inferred); zinc ion binding (inferred); INVOLVED IN epithelial cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (inferred) | 24 | 22722902 | 22871098 | Dog | 27 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12471268 | Cbfa2t2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | ENCODES a protein that exhibits metal ion binding (inferred); transcription corepressor activity (inferred); zinc ion binding (inferred); INVOLVED IN epithelial cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (inferred) | NW_004936561 | 6926856 | 6971062 | Squirrel | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18919193 | Cbfa2t2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | ENCODES a protein that exhibits metal ion binding (inferred); transcription corepressor activity (inferred); zinc ion binding (inferred); INVOLVED IN epithelial cell differentiation (ortholog); intestinal epithelial cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 24 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18696747 | CBFA2T2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | ENCODES a protein that exhibits metal ion binding (inferred); transcription corepressor activity (inferred); zinc ion binding (inferred); INVOLVED IN epithelial cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 27 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155234224 | cbfa2t2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626082495 | Cbfa2t2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | ENCODES a protein that exhibits transcription corepressor activity (ortholog); INVOLVED IN epithelial cell differentiation (ortholog); intestinal epithelial cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN nucleus (ortholog) | | | | Black Rat | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13859707 | CBFA2T2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | ENCODES a protein that exhibits metal ion binding (inferred); transcription corepressor activity (inferred); zinc ion binding (inferred); INVOLVED IN epithelial cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (inferred) | | | | Pig | 27 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155250872 | cbfa2t2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155234225 | cbfa2t2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1619283 | Cbfa2t2-ps1 | CBFA2/RUNX1 translocation partner 2, pseudogene 1 | INTERACTS WITH bisphenol A | 5 | 60388721 | 60389546 | Mouse | 1 | symbol , PhenoGen , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 18926692 | LOC101712376 | protein CBFA2T2-like | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18921902 | LOC106008439 | protein CBFA2T2 pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |