Btbd12 Gene Search Result

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4 records found for search term Btbd12

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1347724	SLX4	SLX4 structure-specific endonuclease subunit	This gene encodes a protein that functions as an assembly component of multiple structure-specific endonucleases. These endonuclease complexes are required for repair of specific types of DNA lesions and critical for cellular responses to replication fork failure. Mutations in this gene were found i ... (more) n patients with Fanconi anemia. [provided by RefSeq, Sep 2016]	16	3581181	3611606	Human	457	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1557108	Slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	This gene encodes a protein containing a BTB (POZ) domain that comprises a subunit of structure-specific endonucleases. The encoded protein aids in the resolution of DNA secondary structures that arise during the processes of DNA repair and recombination. Knock out of this gene in mouse recapitulate ... (more) s the phenotype of the human disease Fanconi anemia, including blood cytopenia and susceptibility to genomic instability. [provided by RefSeq, Dec 2013]	16	3796969	3821708	Mouse	200	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1566009	Slx4	SLX4 structure-specific endonuclease subunit	ENCODES a protein that exhibits enzyme activator activity (ortholog); INVOLVED IN DNA double-strand break processing involved in repair via single-strand annealing (ortholog); DNA repair (ortholog); double-strand break repair via homologous recombination (ortholog); ASSOCIATED WITH breast cancer (or ... (more) tholog); Breast Cancer, Familial (ortholog); Fanconi anemia (ortholog); FOUND IN chromatin (ortholog); chromosome, telomeric region (ortholog); ERCC4-ERCC1 complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil	10	12032131	12055685	Rat	126	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
12279825	SLX4	SLX4 structure-specific endonuclease subunit	ENCODES a protein that exhibits DNA binding (inferred); enzyme activator activity (inferred); metal ion binding (inferred); INVOLVED IN response to intra-S DNA damage checkpoint signaling (ortholog); ASSOCIATED WITH breast cancer (ortholog); Breast Cancer, Familial (ortholog); Fanconi anemia (orthol ... (more) og); FOUND IN chromatin (inferred); chromosome, telomeric region (inferred); ERCC4-ERCC1 complex (inferred)	6	37648297	37666584	Dog	60	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]