| 620344 | Bst1 | bone marrow stromal cell antigen 1 | ENCODES a protein that exhibits NAD+ nucleosidase activity, cyclic ADP-ribose generating (ortholog); INVOLVED IN positive regulation of cell population proliferation (ortholog); regulation of actin cytoskeleton organization (ortholog); regulation of calcium-mediated signaling (ortholog); PARTICIPATE S IN ADP-ribosylation pathway, cyclic ribosylation; niacin metabolic pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH lung disease (ortholog); Parkinson's disease (ortholog); FOUND IN plasma membrane (ortholog); uropod (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 17beta-estradiol 3-benzoate | 14 | 71466179 | 71482671 | Rat | 138 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 732142 | Bst1 | bone marrow stromal cell antigen 1 | Predicted to enable NAD+ nucleosidase activity, cyclic ADP-ribose generating and phosphorus-oxygen lyase activity. Predicted to be involved in several processes, including positive regulation of B cell proliferation; regulation of neutrophil chemotaxis; and regulation of peptidyl-tyrosine phosphoryl ation. Predicted to be located in uropod. Predicted to be active in plasma membrane. Is expressed in cerebellum; forebrain; and spleen white pulp. Orthologous to human BST1 (bone marrow stromal cell antigen 1). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 43976235 | 44000810 | Mouse | 134 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1342632 | BST1 | bone marrow stromal cell antigen 1 | Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow str omal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] | 4 | 15703065 | 15774173 | Human | 137 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8940320 | Bst1 | bone marrow stromal cell antigen 1 | ENCODES a protein that exhibits NAD+ nucleosidase activity, cyclic ADP-ribose generating (ortholog); INVOLVED IN positive regulation of cell population proliferation (ortholog); regulation of actin cytoskeleton organization (ortholog); regulation of calcium-mediated signaling (ortholog); PARTICIPATE S IN ADP-ribosylation pathway, cyclic ribosylation; niacin metabolic pathway; ASSOCIATED WITH lung disease (ortholog); Parkinson's disease (ortholog); FOUND IN plasma membrane (ortholog); uropod (ortholog) | NW_004955480 | 8273887 | 8304127 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11923511 | BST1 | bone marrow stromal cell antigen 1 | ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); NAD+ nucleosidase activity, cyclic ADP-ribose generating (inferred); INVOLVED IN positive regulation of B cell proliferation (inferred); positive regulation of cell population prol iferation (inferred); regulation of actin cytoskeleton organization (inferred); PARTICIPATES IN ADP-ribosylation pathway, cyclic ribosylation; niacin metabolic pathway; ASSOCIATED WITH lung disease (ortholog); Parkinson's disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); uropod (inferred) | 4 | 10154453 | 10183448 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12156431 | BST1 | bone marrow stromal cell antigen 1 | ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); NAD+ nucleosidase activity, cyclic ADP-ribose generating (inferred); INVOLVED IN positive regulation of cell population proliferation (inferred); regulation of actin cytoskeleton o rganization (inferred); regulation of calcium-mediated signaling (inferred); PARTICIPATES IN ADP-ribosylation pathway, cyclic ribosylation; niacin metabolic pathway; ASSOCIATED WITH lung disease (ortholog); Parkinson's disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); uropod (inferred) | 3 | 64617903 | 64641131 | Dog | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12458732 | Bst1 | bone marrow stromal cell antigen 1 | ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); NAD+ nucleosidase activity, cyclic ADP-ribose generating (inferred); INVOLVED IN positive regulation of B cell proliferation (inferred); positive regulation of cell population prol iferation (inferred); regulation of actin cytoskeleton organization (inferred); PARTICIPATES IN ADP-ribosylation pathway, cyclic ribosylation; niacin metabolic pathway; ASSOCIATED WITH lung disease (ortholog); Parkinson's disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); uropod (inferred) | NW_004936477 | 12195323 | 12218261 | Squirrel | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18927462 | Bst1 | bone marrow stromal cell antigen 1 | ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); NAD+ nucleosidase activity, cyclic ADP-ribose generating (inferred); INVOLVED IN positive regulation of cell population proliferation (ortholog); regulation of actin cytoskeleton o rganization (ortholog); regulation of calcium-mediated signaling (ortholog); PARTICIPATES IN ADP-ribosylation pathway, cyclic ribosylation; niacin metabolic pathway; ASSOCIATED WITH lung disease (ortholog); Parkinson's disease (ortholog); FOUND IN uropod (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626073516 | Bst1 | bone marrow stromal cell antigen 1 | ENCODES a protein that exhibits NAD+ nucleosidase activity, cyclic ADP-ribose generating (ortholog); INVOLVED IN positive regulation of cell population proliferation (ortholog); regulation of actin cytoskeleton organization (ortholog); regulation of calcium-mediated signaling (ortholog); PARTICIPATE S IN ADP-ribosylation pathway, cyclic ribosylation; niacin metabolic pathway; ASSOCIATED WITH lung disease (ortholog); Parkinson's disease (ortholog); FOUND IN plasma membrane (ortholog); uropod (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18373983 | BST1 | bone marrow stromal cell antigen 1 | ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); NAD+ nucleosidase activity, cyclic ADP-ribose generating (inferred); INVOLVED IN positive regulation of B cell proliferation (inferred); positive regulation of cell population prol iferation (inferred); regulation of actin cytoskeleton organization (inferred); PARTICIPATES IN ADP-ribosylation pathway, cyclic ribosylation; niacin metabolic pathway; ASSOCIATED WITH lung disease (ortholog); Parkinson's disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); uropod (inferred) | | | | Green Monkey | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14035411 | BST1 | bone marrow stromal cell antigen 1 | ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); NAD+ nucleosidase activity, cyclic ADP-ribose generating (inferred); INVOLVED IN positive regulation of cell population proliferation (inferred); regulation of actin cytoskeleton o rganization (inferred); regulation of calcium-mediated signaling (inferred); PARTICIPATES IN ADP-ribosylation pathway, cyclic ribosylation; niacin metabolic pathway; ASSOCIATED WITH lung disease (ortholog); Parkinson's disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); uropod (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14375496 | BST1 | | | | | | Yeast | | symbol | gene, null |
| 38663976 | BST1-AS1 | BST1 antisense RNA 1 | | 4 | 15754071 | 15756426 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna, MODEL [RefSeq] |
| 1605037 | PGAP1 | post-GPI attachment to proteins inositol deacylase 1 | The protein encoded by this gene functions early in the glycosylphosphatidylinositol (GPI) biosynthetic pathway, catalyzing the inositol deacylation of GPI. The encoded protein is required for the production of GPI that can attach to proteins, and this may be an important factor in the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi. Defects in this gene are a cause an autosomal recessive form of cognitive impairment. [provided by RefSeq, Jul 2017] | 2 | 196833004 | 196926707 | Human | 236 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 68543 | SCRG1 | stimulator of chondrogenesis 1 | Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly included in the membrane or secreted by the cells due to it s hydrophobic N-terminus. In addition, the encoded protein can interact with bone marrow stromal cell antigen 1 (BST1) to enhance the differentiation potentials of human mesenchymal stem cells during tissue and bone regeneration. [provided by RefSeq, Jul 2016] | 4 | 173384701 | 173519144 | Human | 73 | description | gene, protein-coding, REVIEWED [RefSeq] |