| 1304635 | Atp6v1g3 | ATPase H+ transporting V1 subunit G3 | ENCODES a protein that exhibits ATPase binding (ortholog); proton-transporting ATPase activity, rotational mechanism (ortholog); INVOLVED IN monoatomic ion transport (inferred); proton transmembrane transport (inferred); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheuma toid arthritis pathway; FOUND IN cytosol; plasma membrane; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 13 | 52351787 | 52376784 | Rat | 54 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312186 | ATP6V1G3 | ATPase H+ transporting V1 subunit G3 | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated en docytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 1 | 198523222 | 198540945 | Human | 51 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312187 | Atp6v1g3 | ATPase, H+ transporting, lysosomal V1 subunit G3 | Enables proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in synaptic vesicle lumen acidification. Predicted to act upstream of or within proton transmembrane transport. Located in cytosol and plasma membrane. Is expressed in embryo; forelimb bud; metanephros; and o lfactory epithelium. Orthologous to human ATP6V1G3 (ATPase H+ transporting V1 subunit G3). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 138201476 | 138217200 | Mouse | 56 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8777360 | Atp6v1g3 | ATPase H+ transporting V1 subunit G3 | ENCODES a protein that exhibits ATPase binding (ortholog); proton-transporting ATPase activity, rotational mechanism (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog) | NW_004955406 | 34910498 | 34927745 | Chinchilla | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11853571 | ATP6V1G3 | ATPase H+ transporting V1 subunit G3 | ENCODES a protein that exhibits ATP hydrolysis activity (inferred); ATPase binding (inferred); proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN monoatomic ion transport (inferred); proton transmembrane transport (inferred); synaptic vesicle lumen acidification (infer red); FOUND IN cytosol (inferred); membrane (inferred); plasma membrane (inferred) | 1 | 174130976 | 174148524 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12073595 | ATP6V1G3 | ATPase H+ transporting V1 subunit G3 | ENCODES a protein that exhibits ATPase binding (inferred); proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN monoatomic ion transport (inferred); proton transmembrane transport (inferred); FOUND IN cytosol (inferred); plasma membrane (inferred); vacuolar proton-transp orting V-type ATPase complex (inferred) | 7 | 4368476 | 4388544 | Dog | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12563244 | Atp6v1g3 | ATPase H+ transporting V1 subunit G3 | ENCODES a protein that exhibits ATP hydrolysis activity (inferred); ATPase binding (inferred); proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN monoatomic ion transport (inferred); proton transmembrane transport (inferred); synaptic vesicle lumen acidification (infer red); FOUND IN cytosol (inferred); plasma membrane (inferred); synaptic vesicle membrane (inferred) | NW_004936567 | 5461760 | 5476893 | Squirrel | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18538929 | ATP6V1G3 | ATPase H+ transporting V1 subunit G3 | ENCODES a protein that exhibits ATP hydrolysis activity (inferred); ATPase binding (inferred); proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN monoatomic ion transport (inferred); proton transmembrane transport (inferred); synaptic vesicle lumen acidification (infer red); FOUND IN cytosol (inferred); plasma membrane (inferred); synaptic vesicle membrane (inferred) | | | | Green Monkey | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18902290 | Atp6v1g3 | ATPase H+ transporting V1 subunit G3 | ENCODES a protein that exhibits ATPase binding (ortholog); INVOLVED IN monoatomic ion transport (inferred); proton transmembrane transport (inferred); synaptic vesicle lumen acidification (inferred); FOUND IN cytosol (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14041956 | ATP6V1G3 | ATPase H+ transporting V1 subunit G3 | ENCODES a protein that exhibits ATPase binding (inferred); proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN monoatomic ion transport (inferred); proton transmembrane transport (inferred); FOUND IN cytosol (inferred); plasma membrane (inferred); vacuolar proton-transp orting V-type ATPase complex (inferred) | | | | Pig | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155252085 | atp6v1g3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625924988 | Atp6v1g3 | ATPase H+ transporting V1 subunit G3 | ENCODES a protein that exhibits ATPase binding (ortholog); proton-transporting ATPase activity, rotational mechanism (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog) | | | | Black Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257137 | atp6v1g3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155252087 | atp6v1g3.S | | | | | | African Clawed Frog | | symbol | gene, null |