| 1307379 | Asap1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits GTPase activator activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cilium assembly (ortholog); negative regulation of dendritic spine development (ortholog); positive regulation of membrane tubulation (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; endocytosis pathway; Fc gamma receptor mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; all-trans-retinoic acid | 7 | 97675354 | 97982523 | Rat | 176 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1316545 | Asap1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain1 | Enables GTPase activator activity and phospholipid binding activity. Involved in regulation of postsynapse organization. Acts upstream of or within negative regulation of dendritic spine development and positive regulation of membrane tubulation. Located in dendritic spine and podosome. Is active in glutamatergic synapse. Is expressed in several structures, including gonad; hemolymphoid system; limb; long bone; and nervous system. Orthologous to human ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 63958704 | 64254922 | Mouse | 204 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1354069 | ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cyt oskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] | 8 | 130052104 | 130443674 | Human | 167 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8706460 | Asap1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits GTPase activator activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cilium assembly (ortholog); negative regulation of dendritic spine development (ortholog); positive regulation of membrane tubulation (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog) | NW_004955461 | 4813228 | 5083548 | Chinchilla | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11687455 | ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN negative regulation of dendritic spine development (ortholog); positive regulation of membrane tub ulation (ortholog); positive regulation of podosome assembly (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog) | 8 | 126688608 | 127080662 | Bonobo | 51 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12260060 | ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN negative regulation of dendritic spine development (ortholog); positive regulation of membrane tub ulation (ortholog); positive regulation of podosome assembly (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog) | 13 | 27111785 | 27468476 | Dog | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12464072 | Asap1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN negative regulation of dendritic spine development (ortholog); positive regulation of membrane tub ulation (ortholog); positive regulation of podosome assembly (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog) | NW_004936470 | 18340120 | 18640396 | Squirrel | 51 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18900491 | Asap1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN negative regulation of dendritic spine development (ortholog); positive regulation of membrane tub ulation (ortholog); positive regulation of podosome assembly (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog) | | | | Naked Mole-Rat | 49 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14149249 | ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN negative regulation of dendritic spine development (ortholog); positive regulation of membrane tub ulation (ortholog); positive regulation of podosome assembly (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog) | | | | Pig | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18774495 | ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN negative regulation of dendritic spine development (ortholog); positive regulation of membrane tub ulation (ortholog); positive regulation of podosome assembly (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog) | | | | Green Monkey | 51 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626142951 | Asap1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits GTPase activator activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cilium assembly (ortholog); negative regulation of dendritic spine development (ortholog); positive regulation of membrane tubulation (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog) | | | | Black Rat | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234447 | asap1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155252929 | asap1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155246122 | asap1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1602895 | ASAP1-IT1 | ASAP1 intronic transcript 1 | INTERACTS WITH 2-hydroxypropanoic acid; beta-naphthoflavone; cadmium dichloride | 8 | 130295355 | 130296533 | Human | 18 | symbol , GTEx , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
| 7252018 | ASAP1-IT2 | ASAP1 intronic transcript 2 | INTERACTS WITH 2-hydroxypropanoic acid; dorsomorphin; methylmercury chloride | 8 | 130082738 | 130084768 | Human | 8 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16571648 | LOC124902026 | uncharacterized LOC124902026 | | 8 | 130358767 | 130362495 | Human | | old_gene_name | gene, ncrna, MODEL [RefSeq] |
| 16572293 | LOC124902027 | uncharacterized LOC124902027 | | 8 | 130248175 | 130251051 | Human | | old_gene_name | gene, ncrna, MODEL [RefSeq] |