| 1309772 | Api5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (inferred); INVOLVED IN apoptotic process (inferred); negative regulation of apoptotic process (inferred); ASSOCIATED WITH cervical cancer (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred); spliceosomal complex (inferre d); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 3 | 100833417 | 100858580 | Rat | 37 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1320289 | Api5 | apoptosis inhibitor 5 | Predicted to enable RNA binding activity and fibroblast growth factor binding activity. Acts upstream of or within negative regulation of fibroblast apoptotic process. Part of spliceosomal complex. Is expressed in several structures, including central nervous system and retina. Orthologous to human API5 (apoptosis inhibitor 5). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 94242073 | 94268490 | Mouse | 85 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8745906 | Api5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of fibroblast apoptotic process (ortholog); FOUND IN nuclear speck (ortholog); nucleus (ortholog); spliceosomal complex (ortholog) | NW_004955422 | 4121913 | 4149242 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11790186 | API5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (inferred); RNA binding (inferred); INVOLVED IN negative regulation of fibroblast apoptotic process (ortholog); FOUND IN spliceosomal complex (ortholog) | 11 | 43279024 | 43311602 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12104840 | API5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (inferred); INVOLVED IN apoptotic process (inferred); negative regulation of apoptotic process (inferred); ASSOCIATED WITH cervical cancer (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred); spliceosomal complex (inferre d) | 18 | 26326387 | 26355580 | Dog | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12703173 | Api5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (inferred); RNA binding (inferred); INVOLVED IN negative regulation of fibroblast apoptotic process (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred); spliceosomal complex (inferred) | NW_004936562 | 5229157 | 5253175 | Squirrel | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625786595 | API5 | apoptosis inhibitor 5 | This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragment ation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] | 11 | 43311996 | 43344529 | Human | 83 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 18903646 | Api5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); INVOLVED IN negative regulation of fibroblast apoptotic process (ortholog); FOUND IN nuclear speck (ortholog); spliceosomal complex (ortholog) | | | | Naked Mole-Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14280981 | API5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (inferred); INVOLVED IN negative regulation of fibroblast apoptotic process (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred); spliceosomal complex (inferred) | | | | Pig | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18690895 | API5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (inferred); RNA binding (inferred); INVOLVED IN negative regulation of fibroblast apoptotic process (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred); spliceosomal complex (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625893749 | Api5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of fibroblast apoptotic process (ortholog); FOUND IN nuclear speck (ortholog); nucleus (ortholog); spliceosomal complex (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240629 | api5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155249167 | api5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155249454 | api5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 5143522 | Api5-ps | apoptosis inhibitor 5, pseudogene | | 7 | 26618198 | 26618764 | Mouse | | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 1596759 | Api5-ps1 | apoptosis inhibitor 5, pseudogene 1 | | 18 | 11911288 | 11921608 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1592316 | Api5-ps2 | apoptosis inhibitor 5, pseudogene 2 | | 10 | 25974820 | 25976480 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1320288 | API5P1 | apoptosis inhibitor 5 pseudogene 1 | ASSOCIATED WITH cervical cancer; INTERACTS WITH cyclosporin A; lead diacetate; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (ortholog) | X | 116104366 | 116108497 | Human | 24 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 16560488 | AC087276.2 | novel transcript, antisense to API5 and TTC17 | | | | | Human | | name | gene, lncrna |
| 4144507 | API5P2 | apoptosis inhibitor 5 pseudogene 2 | | 2 | 177994817 | 177998877 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |