| 1351282 | APCDD1 | APC down-regulated 1 | This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.[provided by RefSeq, Sep 2010] | 18 | 10454635 | 10489949 | Human | 140 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1589962 | Apcdd1 | APC down-regulated 1 | ENCODES a protein that exhibits identical protein binding (ortholog); Wnt-protein binding (ortholog); INVOLVED IN astrocyte cell migration (ortholog); hair follicle development (ortholog); negative regulation of Wnt signaling pathway (ortholog); ASSOCIATED WITH hypotrichosis 1 (ortholog); obesity (o rtholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 18 | 58655696 | 58686359 | Rat | 125 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1619610 | Apcdd1 | adenomatosis polyposis coli down-regulated 1 | Predicted to enable Wnt-protein binding activity and identical protein binding activity. Involved in regulation of odontogenesis of dentin-containing tooth. Acts upstream of or within astrocyte cell migration. Predicted to be active in plasma membrane. Is expressed in several structures, including a limentary system; brain; branchial arch; ear; and reproductive system. Human ortholog(s) of this gene implicated in hypotrichosis 1. Orthologous to human APCDD1 (APC down-regulated 1). [provided by Alliance of Genome Resources, Apr 2025] | 18 | 63055398 | 63086886 | Mouse | 144 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8962160 | Apcdd1 | APC down-regulated 1 | ENCODES a protein that exhibits identical protein binding (ortholog); Wnt-protein binding (ortholog); INVOLVED IN astrocyte cell migration (ortholog); hair follicle development (ortholog); negative regulation of Wnt signaling pathway (ortholog); ASSOCIATED WITH hypotrichosis 1 (ortholog); obesity (o rtholog); FOUND IN plasma membrane (ortholog) | NW_004955402 | 1932685 | 1947680 | Chinchilla | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12035068 | APCDD1 | APC down-regulated 1 | ENCODES a protein that exhibits identical protein binding (inferred); Wnt-protein binding (inferred); INVOLVED IN astrocyte cell migration (ortholog); regulation of odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH hypotrichosis 1 (ortholog); obesity (ortholog); FOUND IN plasma me mbrane (inferred) | 18 | 3799425 | 3834557 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12382367 | APCDD1 | APC down-regulated 1 | ENCODES a protein that exhibits identical protein binding (inferred); Wnt-protein binding (inferred); INVOLVED IN astrocyte cell migration (ortholog); regulation of odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH hypotrichosis 1 (ortholog); obesity (ortholog); FOUND IN plasma me mbrane (inferred) | 7 | 76336502 | 76368695 | Dog | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12601176 | Apcdd1 | APC down-regulated 1 | ENCODES a protein that exhibits identical protein binding (inferred); Wnt-protein binding (inferred); INVOLVED IN astrocyte cell migration (ortholog); ASSOCIATED WITH hypotrichosis 1 (ortholog); obesity (ortholog); FOUND IN plasma membrane (inferred) | NW_004936626 | 1217240 | 1237741 | Squirrel | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13922373 | APCDD1 | APC down-regulated 1 | ENCODES a protein that exhibits identical protein binding (inferred); Wnt-protein binding (inferred); INVOLVED IN astrocyte cell migration (ortholog); ASSOCIATED WITH hypotrichosis 1 (ortholog); obesity (ortholog); FOUND IN plasma membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 20 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626163321 | Apcdd1 | APC down-regulated 1 | ENCODES a protein that exhibits identical protein binding (ortholog); Wnt-protein binding (ortholog); INVOLVED IN astrocyte cell migration (ortholog); hair follicle development (ortholog); negative regulation of Wnt signaling pathway (ortholog); ASSOCIATED WITH hypotrichosis 1 (ortholog); obesity (o rtholog); FOUND IN plasma membrane (ortholog) | | | | Black Rat | 11 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18908814 | Apcdd1 | APC down-regulated 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN astrocyte cell migration (ortholog); hair follicle development (ortholog); regulation of odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH hypotrichosis 1 (ortholog); obesity (ortholog); FOUND IN pla sma membrane (inferred) | | | | Naked Mole-Rat | 16 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18758950 | APCDD1 | APC down-regulated 1 | ENCODES a protein that exhibits identical protein binding (inferred); Wnt-protein binding (inferred); INVOLVED IN astrocyte cell migration (ortholog); regulation of odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH hypotrichosis 1 (ortholog); obesity (ortholog); FOUND IN plasma me mbrane (inferred) | | | | Green Monkey | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155243724 | apcdd1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155245046 | apcdd1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155254443 | apcdd1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 15567365 | AL844849.1 | adenomatosis polyposis coli down-regulated 1 (Apcdd1) pseudogene | | | | | Mouse | | name | gene, processed_pseudogene |
| 1562045 | Apcdd1l | APC down-regulated 1 like | ENCODES a protein that exhibits Wnt-protein binding (inferred); INVOLVED IN negative regulation of Wnt signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH atrazine; bisphenol A; methoxychlor | 3 | 183000504 | 183076628 | Rat | 51 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1605849 | APCDD1L | APC down-regulated 1 like | Predicted to enable Wnt-protein binding activity. Predicted to be involved in negative regulation of Wnt signaling pathway. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 20 | 58459101 | 58515399 | Human | 51 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 11988359 | APCDD1L | APC down-regulated 1 like | ENCODES a protein that exhibits Wnt-protein binding (inferred); INVOLVED IN negative regulation of Wnt signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 20 | 54805503 | 54862730 | Bonobo | 5 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12374141 | APCDD1L | APC down-regulated 1 like | ENCODES a protein that exhibits Wnt-protein binding (inferred); INVOLVED IN negative regulation of Wnt signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 24 | 43246619 | 43298634 | Dog | 5 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14108037 | APCDD1L | APC down-regulated 1 like | ENCODES a protein that exhibits Wnt-protein binding (inferred); INVOLVED IN negative regulation of Wnt signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 5 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18581864 | APCDD1L | APC down-regulated 1 like | ENCODES a protein that exhibits Wnt-protein binding (inferred); INVOLVED IN negative regulation of Wnt signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 5 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18908023 | Apcdd1l | APC down-regulated 1 like | ENCODES a protein that exhibits Wnt-protein binding (inferred); INVOLVED IN negative regulation of Wnt signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 5 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 625970801 | Apcdd1l | APC down-regulated 1 like | | | | | Black Rat | 1 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 8704588 | Apcdd1l | APC down-regulated 1 like | | NW_004955445 | 1025597 | 1070385 | Chinchilla | 1 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12581883 | Apcdd1l | APC down-regulated 1 like | | NW_004936530 | 1045340 | 1159638 | Squirrel | 1 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 598151002 | apcdd1l | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 6892856 | APCDD1L-DT | APCDD1L divergent transcript | INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2-hydroxypropanoic acid; aflatoxin B1 | 20 | 58515379 | 58619892 | Human | 14 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
